TLR-3 and TLR-7/8 ligands indirectly activate Langerhans cells when intradermally injected by triggering the recruitment of inflammatory cells

por Epaulard, O, Adam, L, Le Grand, R, Martinon, F
Publicado 2012

P19-25. A vaccine model to prevent the depletion of uninfected bystander CD4 cells during HIV infection

por Vieillard, V, Fausther-Bovendo, H, Le Grand, R, Debre, P
Publicado 2009

P17-16. Anti-Langerin-HIV Gag p24 fusion protein targeting Langerhans cells as a new anti-HIV vaccine strategy

por Culina, S, Zurawsky, G, Flamar, A, Brochard, P, Delache, B, Banchereau, J, Le Grand, R, Martinon, F
Publicado 2009

P18-08. Characterization of CD34+ derived dendritic cells generated in vitro and transfected with HIV gene as potential therapeutic vaccine in macaque

por Romain, G, Van Gulck, E, Zurawski, G, Banchereau, J, Vanham, G, Le Grand, R, Martinon, F
Publicado 2009

P11-15. Induction of a mucosal immune response to HIV after systemic immunization with poly(lactic acid) nanoparticles formulated with gag antigen and polyI:C

por Primard, C, Weber, C, Martinon, F, Munier, S, Calamel, A, Luciani, E, Delair, T, Le Grand, R, Verrier, B
Publicado 2009

SARS-COV-2 infection causes massive lung-cell senescence

por Born, E., Maisonnasse, P., Fouillade, C., Pascal, Q., Marcos, E., Londono-Vallejo, A., Le Grand, R., Adnot, S., Lipskaia, L.
Publicado 2022

P19-26. Directing macaque immune responses with an anti-dendritic cell HIV Gag p24 fusion protein vaccine

por Martinon, F, Dereuddre-Bosquet, N, Méderlé-Mangeot, I, Flamar, A, Zurawski, S, Verrier, B, Oh, S, Zurawski, G, Banchereau, J, Le Grand , R
Publicado 2009

Non-neutralizing IgG anti-PID antibodies decreased viral load following high dose vaginal challenge of non-human primates

por Moog, C, Dereuddre-Bosquet, N, Biedma, M, Schmidt, S, Decoville, T, Mangeot, I, Zolla-Pazner, S, Vcelar, B, Katinger, D, Holl, V, Le Grand, R
Publicado 2012

Targeting HIV Gag p24 to DICR on dendritic cells induces T cell and potent and long-lasting antibody responses in non-human primates

por Flamar, A, Le Grand, R, Contreras, V, Zurawski, S, Dereuddre-Bosquet, N, Mangeot, I, Martinon, F, Oh, S, Banchereau, J, Zurawski, G, Levy, Y
Publicado 2012

OA05-03. Efficacy study of a T-cell-based DNA vaccine delivered by intradermal electrotransfer in macaques

por Dereuddre-Bosquet, N, Baron, M, Méderlé-Mangeot, I, Kaldma, K, Sikut, R, Männik, A, Stanescu, I, Ustav, M, Le Grand, R, Martinon, F
Publicado 2009

P17-11. HIV DNA vaccine delivery in association with electroporation in the skin of nonhuman primates

por Culina, S, Mannioui, A, Kaldma, K, Sikut, R, Adojaan, M, Männik, A, Toots, U, Kivisild, T, Stanescu, I, Ustav, M, Le Grand, R, Martinon, F
Publicado 2009

Mapping of SIVmac T-cell epitopes in cynomolgus macaques immunized with auxo-GTU-MultiSIV DNA by the intradermal route followed by electroporation

por Corneau, A, Maciel Da Silva, B, Even, S, Morin, J, Sylla, N, Martinon, F, Aarninck, A, Blancher, A, Stanescu, I, Le Grand, R, Dereuddre-Bosquet, N
Publicado 2012

Le traitement par rituximab diminue la réponse humorale, mais pas la réponse cellulaire, après vaccination anti-SARS-CoV-2 chez des patients atteints de maladie auto-immune

por Bitoun, S., Henry, J., Vauloup Fellous, C., Joly, C., Desjardins, D., Bitu, M., Seror, R., Mouna, L., Le Grand, R., Roque Afonso, A.M., Mariette, X.
Publicado 2021

P17-10. A new AuxoGTU-HIV B DNA vaccine induce very long lasting HIV specific T cells response which is efficiently boosted with HIV LAI lipopeptides

por Mangeot-Méderlé, I, Sylla, N, Corneau, A, Langlois, S, Sikut, R, Kaldma, K, Stanescu, I, Ustav, M, Lévy, Y, Derreudre-Bosquet, N, Le-Grand, R, Martinon, F
Publicado 2009

Loss and regain of SIV control upon CD8+ cell depletion in vivo in SIV-controller macaques is not associated with efficient SIV specific CD8+ T-cells

por Hamimi, C, Bruel, T, Dereuddre-Bosquet, N, Cosma, A, Shin, S, Corneau, A, Versmisse, P, Torres, C, Delache, B, Even, S, Guenounou, S, Targat, B, Malleret, B, Karlsson, I, Barré-Sinoussi, F, Le-Grand, R, Pancino, G, Saez-Cirion, A, Vaslin, B
Publicado 2012

Liposomal formulation of Gp41 derivate with adjuvant MPLA: vaccine design, immunogenicity in animals and safety in humans

por Katinger, D, Wagner, A, Luque, I, Crespillo, S, Conejero-Lara, F, Roger, M, Martin, C, Mouz, N, Mourao, S, Farsang, A, Notka, F, Malcolm, K, Bosquet, N, Le Grand, R, Moog, C, Cope, A, Shattock, R, Lewis, DJ, El Habib, R
Publicado 2012

Emerging preclinical evidence does not support broad use of hydroxychloroquine in COVID-19 patients

por Funnell, S. G. P., Dowling, W. E., Muñoz-Fontela, C., Gsell, P.-S., Ingber, D. E., Hamilton, G. A., Delang, L., Rocha-Pereira, J., Kaptein, S., Dallmeier, K. H., Neyts, J., Rosenke, K., de Wit, E., Feldmann, H., Maisonnasse, P., Le Grand, R., Frieman, M. B., Coleman, C. M.
Publicado 2020

Fine-mapping the immunodominant antibody epitopes on consensus sequence-based HIV-1 envelope trimer vaccine candidates

por Reiss, E. I. M. M., van Haaren, M. M., van Schooten, J., Claireaux, M. A. F., Maisonnasse, P., Antanasijevic, A., Allen, J. D., Bontjer, I., Torres, J. L., Lee, W-H, Ozorowski, G., Vázquez Bernat, N., Kaduk, M., Aldon, Y., Burger, J. A., Chawla, H., Aartse, A., Tolazzi, M., Gao, H., Mundsperger, P., Crispin, M., Montefiori, D. C., Karlsson Hedestam, G. B., Scarlatti, G., Ward, A. B., Le Grand, R., Shattock, R., Dereuddre-Bosquet, N., Sanders, R. W., van Gils, M. J.
Publicado 2022

COVA1-18 neutralizing antibody protects against SARS-CoV-2 in three preclinical models

por Maisonnasse, P, Aldon, Y, Marc, A, Marlin, R, Dereuddre-Bosquet, N, Kuzmina, NA, Freyn, AW, Snitselaar, JL, Gonçalves, A, Caniels, TG, Burger, JA, Poniman, M, Chesnais, V, Diry, S, Iershov, A, Ronk, AJ, Jangra, S, Rathnasinghe, R, Brouwer, PJM, Bijl, TPL, van Schooten, J, Brinkkemper, M, Liu, H, Yuan, M, Mire, CE, van Breemen, MJ, Contreras, V, Naninck, T, Lemaître, J, Kahlaoui, N, Relouzat, F, Chapon, C, Ho Tsong Fang, R, McDanal, C, Osei-Twum, M, St-Amant, N, Gagnon, L, Montefiori, DC, Wilson, IA, Ginoux, E, de Bree, GJ, García-Sastre, A, Schotsaert, M, Coughlan, L, Bukreyev, A, van der Werf, S, Guedj, J, Sanders, RW, van Gils, MJ, Le Grand, R
Publicado 2021