To be or not to be a piRNA: genomic origin and processing of piRNAs

por Le Thomas, Adrien, Tóth, Katalin Fejes, Aravin, Alexei A
Publicado 2014

Pumilio protects Xbp1 mRNA from regulated Ire1-dependent decay

por Cairrão, Fátima, Santos, Cristiana C., Le Thomas, Adrien, Marsters, Scot, Ashkenazi, Avi, Domingos, Pedro M.
Publicado 2022

Neuronal regulated ire-1-dependent mRNA decay controls germline differentiation in Caenorhabditis elegans

por Levi-Ferber, Mor, Shalash, Rewayd, Le-Thomas, Adrien, Salzberg, Yehuda, Shurgi, Maor, Benichou, Jennifer IC, Ashkenazi, Avi, Henis-Korenblit, Sivan
Publicado 2021

Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing

por Le Thomas, Adrien, Stuwe, Evelyn, Li, Sisi, Du, Jiamu, Marinov, Georgi, Rozhkov, Nikolay, Chen, Yung-Chia Ariel, Luo, Yicheng, Sachidanandam, Ravi, Toth, Katalin Fejes, Patel, Dinshaw, Aravin, Alexei A.
Publicado 2014

Antigen-derived peptides engage the ER stress sensor IRE1α to curb dendritic cell cross-presentation

por Guttman, Ofer, Le Thomas, Adrien, Marsters, Scot, Lawrence, David A., Gutgesell, Lauren, Zuazo-Gaztelu, Iratxe, Harnoss, Jonathan M., Haag, Simone M., Murthy, Aditya, Strasser, Geraldine, Modrusan, Zora, Wu, Thomas, Mellman, Ira, Ashkenazi, Avi
Publicado 2022

Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α

por Le Thomas, Adrien, Ferri, Elena, Marsters, Scot, Harnoss, Jonathan M., Lawrence, David A., Zuazo-Gaztelu, Iratxe, Modrusan, Zora, Chan, Sara, Solon, Margaret, Chalouni, Cécile, Li, Weihan, Koeppen, Hartmut, Rudolph, Joachim, Wang, Weiru, Wu, Thomas D., Walter, Peter, Ashkenazi, Avi
Publicado 2021

Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands

por Ferri, Elena, Le Thomas, Adrien, Wallweber, Heidi Ackerly, Day, Eric S., Walters, Benjamin T., Kaufman, Susan E., Braun, Marie-Gabrielle, Clark, Kevin R., Beresini, Maureen H., Mortara, Kyle, Chen, Yung-Chia A., Canter, Breanna, Phung, Wilson, Liu, Peter S., Lammens, Alfred, Ashkenazi, Avi, Rudolph, Joachim, Wang, Weiru
Publicado 2020

Disruption of IRE1α through its kinase domain attenuates multiple myeloma

por Harnoss, Jonathan M., Le Thomas, Adrien, Shemorry, Anna, Marsters, Scot A., Lawrence, David A., Lu, Min, Chen, Yung-Chia Ariel, Qing, Jing, Totpal, Klara, Kan, David, Segal, Ehud, Merchant, Mark, Reichelt, Mike, Ackerly Wallweber, Heidi, Wang, Weiru, Clark, Kevin, Kaufman, Susan, Beresini, Maureen H., Laing, Steven T., Sandoval, Wendy, Lorenzo, Maria, Wu, Jiansheng, Ly, Justin, De Bruyn, Tom, Heidersbach, Amy, Haley, Benjamin, Gogineni, Alvin, Weimer, Robby M., Lee, Dong, Braun, Marie-Gabrielle, Rudolph, Joachim, VanWyngarden, Michael J., Sherbenou, Daniel W., Gomez-Bougie, Patricia, Amiot, Martine, Acosta-Alvear, Diego, Walter, Peter, Ashkenazi, Avi
Publicado 2019