Advanced Cancer Imaging Applied in the Comparative Setting

por Vail, David M., LeBlanc, Amy K., Jeraj, Robert
Publicado 2020

Impact of limb amputation and cisplatin chemotherapy on metastatic progression in mouse models of osteosarcoma

por Ren, L., Huang, S., Beck, J., LeBlanc, Amy K.
Publicado 2021

Metabolomics uncovers a link between inositol metabolism and osteosarcoma metastasis

por Ren, Ling, Hong, Ellen S., Mendoza, Arnulfo, Issaq, Sameer, Hoang, Christine Tran, Lizardo, Michael, LeBlanc, Amy, Khanna, Chand
Publicado 2017

Deep Domain Adversarial Learning for Species-Agnostic Classification of Histologic Subtypes of Osteosarcoma

por Patkar, Sushant, Beck, Jessica, Harmon, Stephanie, Mazcko, Christina, Turkbey, Baris, Choyke, Peter, Brown, G. Thomas, LeBlanc, Amy
Publicado 2023

Transcriptomic profiling in canines and humans reveals cancer specific gene modules and biological mechanisms common to both species

por Tawa, Gregory J., Braisted, John, Gerhold, David, Grewal, Gurmit, Mazcko, Christina, Breen, Matthew, Sittampalam, Gurusingham, LeBlanc, Amy K.
Publicado 2021

Large Scale Comparative Deconvolution Analysis of the Canine and Human Osteosarcoma Tumor Microenvironment Uncovers Conserved Clinically Relevant Subtypes

por Patkar, Sushant, Mannheimer, Josh, Harmon, Stephanie, Mazcko, Christina, Choyke, Peter, Brown, G Tom, Turkbey, Baris, LeBlanc, Amy, Beck, Jessica
Publicado 2023

Relative skeletal distribution of proliferating marrow in the adult dog determined using 3′‐deoxy‐3′‐[(18)F]fluorothymidine

por Rowe, Joshua A., Morandi, Federica, Osborne, Dustin R., Wall, Jonathan S., Kennel, Stephen J., Reed, Robert B., LeBlanc, Amy K.
Publicado 2018

Development of a quantitative pharmacodynamic assay for apoptosis in fixed tumor tissue and its application in distinguishing cytotoxic drug—induced DNA double strand breaks from D...

por Dull, Angie B., Wilsker, Deborah, Hollingshead, Melinda, Mazcko, Christina, Annunziata, Christina M., LeBlanc, Amy K., Doroshow, James H., Kinders, Robert J., Parchment, Ralph E.
Publicado 2018

Transcriptional profiling of canine osteosarcoma identifies prognostic gene expression signatures with translational value for humans

por Mannheimer, Joshua D., Tawa, Gregory, Gerhold, David, Braisted, John, Sayers, Carly M., McEachron, Troy A., Meltzer, Paul, Mazcko, Christina, Beck, Jessica A., LeBlanc, Amy K.
Publicado 2023

Immunohistochemical Characterization of Procaspase-3 Overexpression as a Druggable Target With PAC-1, a Procaspase-3 Activator, in Canine and Human Brain Cancers

por Schlein, Lisa J., Fadl-Alla, Bahaa, Pondenis, Holly C., Lezmi, Stéphane, Eberhart, Charles G., LeBlanc, Amy K., Dickinson, Peter J., Hergenrother, Paul J., Fan, Timothy M.
Publicado 2019

Near infrared photoimmunotherapy targeting bladder cancer with a canine anti-epidermal growth factor receptor (EGFR) antibody

por Nagaya, Tadanobu, Okuyama, Shuhei, Ogata, Fusa, Maruoka, Yasuhiro, Knapp, Deborah W., Karagiannis, Sophia N., Fazekas-Singer, Judit, Choyke, Peter L., LeBlanc, Amy K., Jensen-Jarolim, Erika, Kobayashi, Hisataka
Publicado 2018

Launching a Novel Preclinical Infrastructure: Comparative Oncology Trials Consortium Directed Therapeutic Targeting of TNFα to Cancer Vasculature

por Paoloni, Melissa C., Tandle, Anita, Mazcko, Christina, Hanna, Engy, Kachala, Stefan, LeBlanc, Amy, Newman, Shelley, Vail, David, Henry, Carolyn, Thamm, Douglas, Sorenmo, Karin, Hajitou, Amin, Pasqualini, Renata, Arap, Wadih, Khanna, Chand, Libutti, Steven K.
Publicado 2009

Defining the Pharmacodynamic Profile and Therapeutic Index of NHS-IL12 Immunocytokine in Dogs with Malignant Melanoma

por Paoloni, Melissa, Mazcko, Christina, Selting, Kimberly, Lana, Susan, Barber, Lisa, Phillips, Jeffrey, Skorupski, Katherine, Vail, David, Wilson, Heather, Biller, Barbara, Avery, Anne, Kiupel, Matti, LeBlanc, Amy, Bernhardt, Anna, Brunkhorst, Beatrice, Tighe, Robert, Khanna, Chand
Publicado 2015

Target specificity, in vivo pharmacokinetics, and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma

por Yu, Peter Y., Gardner, Heather L., Roberts, Ryan, Cam, Hakan, Hariharan, Seethalakshmi, Ren, Ling, LeBlanc, Amy K., Xiao, Hui, Lin, Jiayuh, Guttridge, Denis C., Mo, Xiaokui, Bennett, Chad E., Coss, Christopher C., Ling, Yonghua, Phelps, Mitch A., Houghton, Peter, London, Cheryl A.
Publicado 2017

A Comparative Oncology Study of Iniparib Defines Its Pharmacokinetic Profile and Biological Activity in a Naturally-Occurring Canine Cancer Model

por Saba, Corey, Paoloni, Melissa, Mazcko, Christina, Kisseberth, William, Burton, Jenna H., Smith, Annette, Wilson-Robles, Heather, Allstadt, Sara, Vail, David, Henry, Carolyn, Lana, Susan, Ehrhart, E. J., Charles, Brad, Kent, Michael, Lawrence, Jessica, Burgess, Kristine, Borgatti, Antonella, Suter, Steve, Woods, Paul, Gordon, Ira, Vrignaud, Patricia, Khanna, Chand, LeBlanc, Amy K.
Publicado 2016

Comparative Oncology Assessment of a Novel Inhibitor of Valosin-Containing Protein in Tumor-Bearing Dogs

por LeBlanc, Amy K., Mazcko, Christina N., Fan, Timothy M., Vail, David M., Flesner, Brian K., Bryan, Jeffrey N., Li, Shan, Wang, Feng, Harris, Scott, Vargas, Jesse D., Govindharajulu, Jeevan P., Jaganathan, Soumya, Tomaino, Francesca, Srivastava, Apurva K., Chou, Tsui-Fen, Stott, Gordon M., Covey, Joseph M., Mroczkowski, Barbara, Doroshow, James H.
Publicado 2022

Veterinary Cooperative Oncology Group—Common Terminology Criteria for Adverse Events (VCOG‐CTCAE v2) following investigational therapy in dogs and cats

por LeBlanc, Amy K., Atherton, Matthew, Bentley, R. Timothy, Boudreau, C. Elizabeth, Burton, Jenna H., Curran, Kaitlin M., Dow, Steven, Giuffrida, Michelle A., Kellihan, Heidi B., Mason, Nicola J., Oblak, Michelle, Selmic, Laura E., Selting, Kimberly A., Singh, Ameet, Tjostheim, Sonja, Vail, David M., Weishaar, Kristen M., Berger, Erika P., Rossmeisl, John H., Mazcko, Christina
Publicado 2021

MPA(PASS) software enables stitched multiplex, multidimensional EV repertoire analysis and a standard framework for reporting bead-based assays

por Welsh, Joshua A., Killingsworth, Bryce, Kepley, Julia, Traynor, Tim, Cook, Sean, Savage, Jason, Marte, Jenn, Lee, Min-Jung, Maeng, Hoyoung M., Pleet, Michelle L., Magana, Setty, Gorgens, André, Maire, Cecile L., Lamszus, Katrin, Ricklefs, Franz L., Merino, Maria J., Linehan, W. Marston, Greten, Tim, Cooks, Tomer, Harris, Curtis C., Apolo, Andrea, Abdel-Mageed, Asim, Ivanov, Alexander R., Trepel, Jane B., Roth, Matthew, Tkach, Mercedes, Milosavljevic, Aleksandar, Théry, Clotilde, LeBlanc, Amy, Berzofsky, Jay A., Ruppin, Eytan, Aldape, Kenneth, Camphausen, Kevin, Gulley, James L., Ghiran, Ionita, Jacobson, Steve, Jones, Jennifer C.
Publicado 2022

A One Health overview, facilitating advances in comparative medicine and translational research

por Stroud, Cheryl, Dmitriev, Igor, Kashentseva, Elena, Bryan, Jeffrey N., Curiel, David T., Rindt, Hans, Reinero, Carol, Henry, Carolyn J., Bergman, Philip J., Mason, Nicola J., Gnanandarajah, Josephine S., Engiles, Julie B., Gray, Falon, Laughlin, Danielle, Gaurnier-Hausser, Anita, Wallecha, Anu, Huebner, Margie, Paterson, Yvonne, O’Connor, Daniel, Treml, Laura S., Stannard, James P., Cook, James L., Jacobs, Marc, Wyckoff, Gerald J., Likins, Lee, Sabbagh, Ubadah, Skaff, Andrew, Guloy, Amado S., Hays, Harlen D., LeBlanc, Amy K., Coates, Joan R., Katz, Martin L., Lyons, Leslie A., Johnson, Gayle C., Johnson, Gary S., O’Brien, Dennis P., Duan, Dongsheng, Calvet, James P., Gandolfi, Barbara, Baron, David A., Weiss, Mark L., Webster, Debra A., Karanu, Francis N., Robb, Edward J., Harman, Robert J.
Publicado 2016