A peek into cancer-associated fibroblasts: origins, functions and translational impact

por LeBleu, Valerie S., Kalluri, Raghu
Publicado 2018

Effective delivery of STING agonist using exosomes suppresses tumor growth and enhances antitumor immunity

por McAndrews, Kathleen M., Che, Sara P.Y., LeBleu, Valerie S., Kalluri, Raghu
Publicado 2021

Exosome-mediated delivery of CRISPR/Cas9 for targeting of oncogenic Kras(G12D) in pancreatic cancer

por McAndrews, Kathleen M, Xiao, Fei, Chronopoulos, Antonios, LeBleu, Valerie S, Kugeratski, Fernanda G, Kalluri, Raghu
Publicado 2021

Dual reporter genetic mouse models of pancreatic cancer identify an epithelial‐to‐mesenchymal transition‐independent metastasis program

por Chen, Yang, LeBleu, Valerie S, Carstens, Julienne L, Sugimoto, Hikaru, Zheng, Xiaofeng, Malasi, Shruti, Saur, Dieter, Kalluri, Raghu
Publicado 2018

Protection against SARS-CoV-2 by BCG vaccination is not supported by epidemiological analyses

por Hensel, Janine, McAndrews, Kathleen M., McGrail, Daniel J., Dowlatshahi, Dara P., LeBleu, Valerie S., Kalluri, Raghu
Publicado 2020

Exosomes Facilitate Therapeutic Targeting of Oncogenic Kras in Pancreatic Cancer

por Kamerkar, Sushrut, LeBleu, Valerie S., Sugimoto, Hikaru, Yang, Sujuan, Ruivo, Carolina F., Melo, Sonia A., Lee, J. Jack, Kalluri, Raghu
Publicado 2017

Podoplanin(+) tumor lymphatics are rate limiting for breast cancer metastasis

por Chen, Yang, Keskin, Doruk, Sugimoto, Hikaru, Kanasaki, Keizo, Phillips, Patricia E., Bizarro, Lauren, Sharpe, Arlene, LeBleu, Valerie S., Kalluri, Raghu
Publicado 2018

4078 Identification of distinct fibroblast populations with unique roles in pancreatic cancer progression and tumor immunity

por Darpolor, Josephine Kebbeh, Zheng, Xiaofeng, Yang, Sujuan, Sugimoto, Hikaru, Carstens, Julienne, de Sampiao, Pedro Correa, LeBleu, Valerie, Kalluri, Raghu
Publicado 2020

EMT Program is Dispensable for Metastasis but Induces Chemoresistance in Pancreatic Cancer

por Zheng, Xiaofeng, Carstens, Julienne L., Kim, Jiha, Scheible, Matthew, Kaye, Judith, Sugimoto, Hikaru, Wu, Chia-Chin, LeBleu, Valerie S., Kalluri, Raghu
Publicado 2015

Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer

por Carstens, Julienne L., Correa de Sampaio, Pedro, Yang, Dalu, Barua, Souptik, Wang, Huamin, Rao, Arvind, Allison, James P., LeBleu, Valerie S., Kalluri, Raghu
Publicado 2017

Activin–like kinase–3 activity is important for kidney regeneration and reversal of fibrosis

por Sugimoto, Hikaru, LeBleu, Valerie S., Basukonda, Dattatreyamurty, Keck, Peter, Taduri, Gangadhar, Bechtel, Wibke, Okada, Hirokazu, Carlson, William, Bey, Philippe, Rusckowski, Mary, Tampe, Björn, Tampe, Desiree, Kanasaki, Keizo, Zeisberg, Michael, Kalluri, Raghu
Publicado 2012

Engineered immunomodulatory extracellular vesicles derived from epithelial cells acquire capacity for positive and negative T cell co-stimulation in cancer and autoimmunity

por Kugeratski, Fernanda G., LeBleu, Valerie S., Dowlatshahi, Dara P., Sugimoto, Hikaru, Arian, Kent A., Fan, Yibo, Huang, Li, Wells, Danielle, Lilla, Sergio, Hodge, Kelly, Zanivan, Sara, McAndrews, Kathleen M., Kalluri, Raghu
Publicado 2023

Epithelial to Mesenchymal Transition induces cell cycle arrest and parenchymal damage in renal fibrosis

por Lovisa, Sara, LeBleu, Valerie S., Tampe, Björn, Sugimoto, Hikaru, Vadnagara, Komal, Carstens, Julienne L., Wu, Chia–Chin, Hagos, Yohannes, Burckhardt, Birgitta C., Pentcheva–Hoang, Tsvetelina, Nischal, Hersharan, Allison, James P., Zeisberg, Michael, Kalluri, Raghu
Publicado 2015

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation to promote metastasis

por LeBleu, Valerie S., O'Connell, Joyce T., Herrera, Karina N. Gonzalez, Wikman-Kocher, Harriet, Pantel, Klaus, Haigis, Marcia C., de Carvalho, Fernanda Machado, Damascena, Aline, Chinen, Ludmilla Thome Domingos, Rocha, Rafael M., Asara, John M., Kalluri, Raghu
Publicado 2014

Unique somatic variants in DNA from urine exosomes of individuals with bladder cancer

por Zhou, Xunian, Kurywchak, Paul, Wolf-Dennen, Kerri, Che, Sara P.Y., Sulakhe, Dinanath, D’Souza, Mark, Xie, Bingqing, Maltsev, Natalia, Gilliam, T. Conrad, Wu, Chia-Chin, McAndrews, Kathleen M., LeBleu, Valerie S., McConkey, David J., Volpert, Olga V., Pretzsch, Shanna M., Czerniak, Bogdan A., Dinney, Colin P., Kalluri, Raghu
Publicado 2021

Heterogeneous antibodies against SARS-CoV-2 spike receptor binding domain and nucleocapsid with implications for COVID-19 immunity

por McAndrews, Kathleen M., Dowlatshahi, Dara P., Dai, Jianli, Becker, Lisa M., Hensel, Janine, Snowden, Laura M., Leveille, Jennifer M., Brunner, Michael R., Holden, Kylie W., Hopkins, Nikolas S., Harris, Alexandria M., Kumpati, Jerusha, Whitt, Michael A., Lee, J. Jack, Ostrosky-Zeichner, Luis L., Papanna, Ramesha, LeBleu, Valerie S., Allison, James P., Kalluri, Raghu
Publicado 2020

Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular-fibrosis and tumor progression

por Laklai, Hanane, Miroshnikova, Yekaterina A., Pickup, Michael W., Collisson, Eric A., Kim, Grace E., Barrett, Alex S., Hill, Ryan C., Lakins, Johnathon N., Schlaepfer, David D., Mouw, Janna K., LeBleu, Valerie S., Roy, Nilotpal, Novitskiy, Sergey V., Johansen, Julia S., Poli, Valeria, Kalluri, Raghu, Iacobuzio-Donahue, Christine A., Wood, Laura D., Hebrok, Matthias, Hansen, Kirk, Moses, Harold L., Weaver, Valerie M.
Publicado 2016

Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2

por El-Shennawy, Lamiaa, Hoffmann, Andrew D., Dashzeveg, Nurmaa Khund, McAndrews, Kathleen M., Mehl, Paul J., Cornish, Daphne, Yu, Zihao, Tokars, Valerie L., Nicolaescu, Vlad, Tomatsidou, Anastasia, Mao, Chengsheng, Felicelli, Christopher J., Tsai, Chia-Feng, Ostiguin, Carolina, Jia, Yuzhi, Li, Lin, Furlong, Kevin, Wysocki, Jan, Luo, Xin, Ruivo, Carolina F., Batlle, Daniel, Hope, Thomas J., Shen, Yang, Chae, Young Kwang, Zhang, Hui, LeBleu, Valerie S., Shi, Tujin, Swaminathan, Suchitra, Luo, Yuan, Missiakas, Dominique, Randall, Glenn C., Demonbreun, Alexis R., Ison, Michael G., Kalluri, Raghu, Fang, Deyu, Liu, Huiping
Publicado 2022