Mutual Inactivation of Notch Receptors and Ligands Facilitates Developmental Patterning

por Sprinzak, David, Lakhanpal, Amit, LeBon, Lauren, Garcia-Ojalvo, Jordi, Elowitz, Michael B.
Publicado 2011

Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states

por LeBon, Lauren, Lee, Tom V, Sprinzak, David, Jafar-Nejad, Hamed, Elowitz, Michael B
Publicado 2014

Correction: Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states

por LeBon, Lauren, Lee, Tom V, Sprinzak, David, Jafar-Nejad, Hamed, Elowitz, Michael B
Publicado 2014

The small molecule ISRIB rescues the stability and activity of Vanishing White Matter Disease eIF2B mutant complexes

por Wong, Yao Liang, LeBon, Lauren, Edalji, Rohinton, Lim, Hock Ben, Sun, Chaohong, Sidrauski, Carmela
Publicado 2018

Dynamic Ligand Discrimination in the Notch Signaling Pathway

por Nandagopal, Nagarajan, Santat, Leah A., LeBon, Lauren, Sprinzak, David, Bronner, Marianne E., Elowitz, Michael B.
Publicado 2018

Cis Interactions between Notch and Delta Generate Mutually Exclusive Signaling States

por Sprinzak, David, Lakhanpal, Amit, LeBon, Lauren, Santat, Leah A., Fontes, Michelle E., Anderson, Graham A., Garcia-Ojalvo, Jordi, Elowitz, Michael B.
Publicado 2010

Sugar phosphate activation of the stress sensor eIF2B

por Hao, Qi, Heo, Jin-Mi, Nocek, Boguslaw P., Hicks, Kevin G., Stoll, Vincent S., Remarcik, Clint, Hackett, Sean, LeBon, Lauren, Jain, Rinku, Eaton, Dan, Rutter, Jared, Wong, Yao Liang, Sidrauski, Carmela
Publicado 2021

eIF2B activator prevents neurological defects caused by a chronic integrated stress response

por Wong, Yao Liang, LeBon, Lauren, Basso, Ana M, Kohlhaas, Kathy L, Nikkel, Arthur L, Robb, Holly M, Donnelly-Roberts, Diana L, Prakash, Janani, Swensen, Andrew M, Rubinstein, Nimrod D, Krishnan, Swathi, McAllister, Fiona E, Haste, Nicole V, O'Brien, Jonathon J, Roy, Margaret, Ireland, Andrea, Frost, Jennifer M, Shi, Lei, Riedmaier, Stephan, Martin, Kathleen, Dart, Michael J, Sidrauski, Carmela
Publicado 2019