Organotypic liver culture models: Meeting current challenges in toxicity testing

por LeCluyse, Edward L., Witek, Rafal P., Andersen, Melvin E., Powers, Mark J.
Publicado 2012

Early Identification of Clinically Relevant Drug Interactions With the Human Bile Salt Export Pump (BSEP/ABCB11)

por Pedersen, Jenny M., Matsson, Pär, Bergström, Christel A. S., Hoogstraate, Janet, Norén, Agneta, LeCluyse, Edward L., Artursson, Per
Publicado 2013

Interpretable predictive models of genome-wide aryl hydrocarbon receptor-DNA binding reveal tissue-specific binding determinants

por Filipovic, David, Qi, Wenjie, Kana, Omar, Marri, Daniel, LeCluyse, Edward L, Andersen, Melvin E, Cuddapah, Suresh, Bhattacharya, Sudin
Publicado 2023

Development of a microphysiological skin-liver-thyroid Chip3 model and its application to evaluate the effects on thyroid hormones of topically applied cosmetic ingredients under c...

por Tao, Thi-Phuong, Maschmeyer, Ilka, LeCluyse, Edward L., Rogers, Eda, Brandmair, Katrin, Gerlach, Silke, Przibilla, Julia, Kern, Fredy, Genies, Camille, Jacques, Carine, Najjar, Abdulkarim, Schepky, Andreas, Marx, Uwe, Kühnl, Jochen, Hewitt, Nicola J.
Publicado 2023

Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing

por Wetmore, Barbara A., Wambaugh, John F., Allen, Brittany, Ferguson, Stephen S., Sochaski, Mark A., Setzer, R. Woodrow, Houck, Keith A., Strope, Cory L., Cantwell, Katherine, Judson, Richard S., LeCluyse, Edward, Clewell, Harvey J., Thomas, Russell S., Andersen, Melvin E.
Publicado 2015

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of...

por Godoy, Patricio, Hewitt, Nicola J., Albrecht, Ute, Andersen, Melvin E., Ansari, Nariman, Bhattacharya, Sudin, Bode, Johannes Georg, Bolleyn, Jennifer, Borner, Christoph, Böttger, Jan, Braeuning, Albert, Budinsky, Robert A., Burkhardt, Britta, Cameron, Neil R., Camussi, Giovanni, Cho, Chong-Su, Choi, Yun-Jaie, Craig Rowlands, J., Dahmen, Uta, Damm, Georg, Dirsch, Olaf, Donato, María Teresa, Dong, Jian, Dooley, Steven, Drasdo, Dirk, Eakins, Rowena, Ferreira, Karine Sá, Fonsato, Valentina, Fraczek, Joanna, Gebhardt, Rolf, Gibson, Andrew, Glanemann, Matthias, Goldring, Chris E. P., Gómez-Lechón, María José, Groothuis, Geny M. M., Gustavsson, Lena, Guyot, Christelle, Hallifax, David, Hammad, Seddik, Hayward, Adam, Häussinger, Dieter, Hellerbrand, Claus, Hewitt, Philip, Hoehme, Stefan, Holzhütter, Hermann-Georg, Houston, J. Brian, Hrach, Jens, Ito, Kiyomi, Jaeschke, Hartmut, Keitel, Verena, Kelm, Jens M., Kevin Park, B., Kordes, Claus, Kullak-Ublick, Gerd A., LeCluyse, Edward L., Lu, Peng, Luebke-Wheeler, Jennifer, Lutz, Anna, Maltman, Daniel J., Matz-Soja, Madlen, McMullen, Patrick, Merfort, Irmgard, Messner, Simon, Meyer, Christoph, Mwinyi, Jessica, Naisbitt, Dean J., Nussler, Andreas K., Olinga, Peter, Pampaloni, Francesco, Pi, Jingbo, Pluta, Linda, Przyborski, Stefan A., Ramachandran, Anup, Rogiers, Vera, Rowe, Cliff, Schelcher, Celine, Schmich, Kathrin, Schwarz, Michael, Singh, Bijay, Stelzer, Ernst H. K., Stieger, Bruno, Stöber, Regina, Sugiyama, Yuichi, Tetta, Ciro, Thasler, Wolfgang E., Vanhaecke, Tamara, Vinken, Mathieu, Weiss, Thomas S., Widera, Agata, Woods, Courtney G., Xu, Jinghai James, Yarborough, Kathy M., Hengstler, Jan G.
Publicado 2013