Magnetic resonance detects changes in phosphocholine associated with Ras activation and inhibition in NIH 3T3 cells

por Ronen, S M, Jackson, L E, Beloueche, M, Leach, M O
Publicado 2001

Measuring changes in human tumour vasculature in response to therapy using functional imaging techniques

por Anderson, H, Price, P, Blomley, M, Leach, M O, Workman, P
Publicado 2001

The phosphocholine and glycerophosphocholine content of an oestrogen-sensitive rat mammary tumour correlates strongly with growth rate.

por Smith, T. A., Eccles, S., Ormerod, M. G., Tombs, A. J., Titley, J. C., Leach, M. O.
Publicado 1991

Metabolic assessment of the action of targeted cancer therapeutics using magnetic resonance spectroscopy

por Beloueche-Babari, M, Chung, Y-L, Al-Saffar, N M S, Falck-Miniotis, M, Leach, M O
Publicado 2010

A comparison of in vivo and in vitro 31P NMR spectra from human breast tumours: variations in phospholipid metabolism.

por Smith, T. A., Glaholm, J., Leach, M. O., Machin, L., Collins, D. J., Payne, G. S., McCready, V. R.
Publicado 1991

Monitoring temozolomide treatment of low-grade glioma with proton magnetic resonance spectroscopy

por Murphy, P S, Viviers, L, Abson, C, Rowland, I J, Brada, M, Leach, M O, Dzik-Jurasz, A S K
Publicado 2004

Evaluation of lactate detection using selective multiple quantum coherence in phantoms and brain tumours

por Harris, L M, Tunariu, N, Messiou, C, Hughes, J, Wallace, T, DeSouza, N M, Leach, M O, Payne, G S
Publicado 2015

Apoptosis is associated with triacylglycerol accumulation in Jurkat T-cells

por Al-Saffar, N M S, Titley, J C, Robertson, D, Clarke, P A, Jackson, L E, Leach, M O, Ronen, S M
Publicado 2002

Validating a robust double‐quantum‐filtered (1)H MRS lactate measurement method in high‐grade brain tumours

por Payne, G.S., Harris, L.M., Cairns, G.S., Messiou, C., deSouza, N.M., Macdonald, A., Saran, F., Leach, M.O.
Publicado 2016

Extended T2-IVIM model for correction of TE dependence of pseudo-diffusion volume fraction in clinical diffusion-weighted magnetic resonance imaging

por Jerome, N P, d’Arcy, J A, Feiweier, T, Koh, D-M, Leach, M O, Collins, D J, Orton, M R
Publicado 2016

A phase II clinical and pharmacokinetic study of Lonidamine in patients with advanced breast cancer.

por Mansi, J. L., de Graeff, A., Newell, D. R., Glaholm, J., Button, D., Leach, M. O., Payne, G., Smith, I. E.
Publicado 1991

First MRI application of an active breathing coordinator

por Kaza, E, Symonds-Tayler, R, Collins, D J, McDonald, F, McNair, H A, Scurr, E, Koh, D-M, Leach, M O
Publicado 2015

Effects of platinum/taxane based chemotherapy on acute perfusion in human pelvic tumours measured by dynamic MRI

por Lankester, K J, Taylor, N J, Stirling, J J, Boxall, J, D'Arcy, J A, Leach, M O, Rustin, G J S, Padhani, A R
Publicado 2005

Acquired resistance to EGFR tyrosine kinase inhibitors alters the metabolism of human head and neck squamous carcinoma cells and xenograft tumours

por Beloueche-Babari, M, Box, C, Arunan, V, Parkes, H G, Valenti, M, De Haven Brandon, A, Jackson, L E, Eccles, S A, Leach, M O
Publicado 2015

Influence of pH on the uptake of 5-fluorouracil into isolated tumour cells.

por Ojugo, A. S., McSheehy, P. M., Stubbs, M., Alder, G., Bashford, C. L., Maxwell, R. J., Leach, M. O., Judson, I. R., Griffiths, J. R.
Publicado 1998

Psychological impact and acceptability of magnetic resonance imaging and X-ray mammography: the MARIBS Study

por Hutton, J, Walker, L G, Gilbert, F J, Evans, D G, Eeles, R, Kwan-Lim, G E, Thompson, D, Pointon, L J, Sharp, D M, Leach, M O
Publicado 2011

Acute tumour response to the MEK1/2 inhibitor selumetinib (AZD6244, ARRY-142886) evaluated by non-invasive diffusion-weighted MRI

por Beloueche-Babari, M, Jamin, Y, Arunan, V, Walker-Samuel, S, Revill, M, Smith, P D, Halliday, J, Waterton, J C, Barjat, H, Workman, P, Leach, M O, Robinson, S P
Publicado 2013

Magnetic resonance detects metabolic changes associated with chemotherapy-induced apoptosis

por Ronen, S M, DiStefano, F, McCoy, C L, Robertson, D, Smith, T A D, Al-Saffar, N M, Titley, J, Cunningham, D C, Griffiths, J R, Leach, M O, Clarke, P A
Publicado 1999

A phase I study of the nitroimidazole hypoxia marker SR4554 using (19)F magnetic resonance spectroscopy

por Lee, C P, Payne, G S, Oregioni, A, Ruddle, R, Tan, S, Raynaud, F I, Eaton, D, Campbell, M J, Cross, K, Halbert, G, Tracy, M, McNamara, J, Seddon, B, Leach, M O, Workman, P, Judson, I
Publicado 2009

Dichloroacetate induces autophagy in colorectal cancer cells and tumours

por Lin, G, Hill, D K, Andrejeva, G, Boult, J K R, Troy, H, Fong, A-C L F W T, Orton, M R, Panek, R, Parkes, H G, Jafar, M, Koh, D-M, Robinson, S P, Judson, I R, Griffiths, J R, Leach, M O, Eykyn, T R, Chung, Y-L
Publicado 2014