An Essential Role for Interleukin 10 in the Function of Regulatory T Cells That Inhibit Intestinal Inflammation

por Asseman, Chrystelle, Mauze, Smita, Leach, Michael W., Coffman, Robert L., Powrie, Fiona
Publicado 1999

Interleukin-10 Is a Natural Suppressor of Cytokine Production and Inflammation in a Murine Model of Allergic Bronchopulmonary Aspergillosis

por Grünig, Gabriele, Corry, David B., Leach, Michael W., Seymour, Brian W.P., Kurup, Viswanath P., Rennick, Donna M.
Publicado 1997

Correlation of pharmacodynamic activity, pharmacokinetics, and anti-product antibody responses to anti-IL-21R antibody therapeutics following IV administration to cynomolgus monkey...

por Vugmeyster, Yulia, Allen, Scott, Szklut, Pamela, Bree, Andrea, Ryan, Mark, Ma, Margery, Spaulding, Vikki, Young, Deborah, Guay, Heath, Bloom, Laird, Leach, Michael W, O'Toole, Margot, Adkins, Karissa
Publicado 2010

Transgenic Expression of the Chemokine Receptor Encoded by Human Herpesvirus 8 Induces an Angioproliferative Disease Resembling Kaposi's Sarcoma

por Yang, Tong-Yuan, Chen, Shu-Cheng, Leach, Michael W., Manfra, Denise, Homey, Bernhard, Wiekowski, Maria, Sullivan, Lee, Jenh, Chung-Her, Narula, Satwant K., Chensue, Stephen W., Lira, Sergio A.
Publicado 2000

Comparative Nonclinical Assessments of the Proposed Biosimilar PF-05280014 and Trastuzumab (Herceptin(®))

por Hurst, Susan, Ryan, Anne M., Ng, Chee-Keng, McNally, James M., Lorello, Leslie G., Finch, Gregory L., Leach, Michael W., Ploch, Stephen A., Fohey, Josh A., Smolarek, Teresa A.
Publicado 2014

Nonproliferative and Proliferative Lesions of the Gastrointestinal Tract, Pancreas and Salivary Glands of the Rat and Mouse

por Nolte, Thomas, Brander-Weber, Patricia, Dangler, Charles, Deschl, Ulrich, Elwell, Michael R., Greaves, Peter, Hailey, Richard, Leach, Michael W., Pandiri, Arun R., Rogers, Arlin, Shackelford, Cynthia C., Spencer, Andrew, Tanaka, Takuji, Ward, Jerrold M.
Publicado 2016

Nonclinical Evaluation of PF-06438179: A Potential Biosimilar to Remicade(®) (Infliximab)

por Derzi, Mazin, Johnson, Theodore R., Shoieb, Ahmed M., Conlon, Hugh D., Sharpe, Penny, Saati, Andrew, Koob, Sarah, Bolt, Michael W., Lorello, Leslie G., McNally, Jim, Kirchhoff, Carol F., Smolarek, Teresa A., Leach, Michael W.
Publicado 2016

Waiving in vivo studies for monoclonal antibody biosimilar development: National and global challenges

por Chapman, Kathryn, Adjei, Akosua, Baldrick, Paul, da Silva, Antonio, De Smet, Karen, DiCicco, Richard, Hong, Seung Suh, Jones, David, Leach, Michael W., McBlane, James, Ragan, Ian, Reddy, Praveen, Stewart, Donald I. H., Suitters, Amanda, Sims, Jennifer
Publicado 2016

Cytosolic phospholipase A(2)α–deficient mice are resistant to experimental autoimmune encephalomyelitis

por Marusic, Suzana, Leach, Michael W., Pelker, Jeffrey W., Azoitei, Mihai L., Uozumi, Naonori, Cui, Junqing, Shen, Marina W.H., DeClercq, Charlene M., Miyashiro, Joy S., Carito, Brenda A., Thakker, Paresh, Simmons, David L., Leonard, John P., Shimizu, Takao, Clark, James D.
Publicado 2005