Surviving the Heat of the Moment: A Fungal Pathogens Perspective

por Leach, Michelle D., Cowen, Leah E.
Publicado 2013

Membrane Fluidity and Temperature Sensing Are Coupled via Circuitry Comprised of Ole1, Rsp5, and Hsf1 in Candida albicans

por Leach, Michelle D., Cowen, Leah E.
Publicado 2014

Lysine Deacetylases Hda1 and Rpd3 Regulate Hsp90 Function thereby Governing Fungal Drug Resistance

por Robbins, Nicole, Leach, Michelle D., Cowen, Leah E.
Publicado 2012

Functional Divergence of Hsp90 Genetic Interactions in Biofilm and Planktonic Cellular States

por Diezmann, Stephanie, Leach, Michelle D., Cowen, Leah E.
Publicado 2015

Identification of sumoylation targets, combined with inactivation of SMT3, reveals the impact of sumoylation upon growth, morphology, and stress resistance in the pathogen Candida...

por Leach, Michelle D., Stead, David A., Argo, Evelyn, Brown, Alistair J.P.
Publicado 2011

Modelling the Regulation of Thermal Adaptation in Candida albicans, a Major Fungal Pathogen of Humans

por Leach, Michelle D., Tyc, Katarzyna M., Brown, Alistair J. P., Klipp, Edda
Publicado 2012

Role of the heat shock transcription factor, Hsf1, in a major fungal pathogen that is obligately associated with warm-blooded animals

por Nicholls, Susan, Leach, Michelle D, Priest, Claire L, Brown, Alistair J P
Publicado 2009

Molecular and proteomic analyses highlight the importance of ubiquitination for the stress resistance, metabolic adaptation, morphogenetic regulation and virulence of Candida albic...

por Leach, Michelle D, Stead, David A, Argo, Evelyn, MacCallum, Donna M, Brown, Alistair J P
Publicado 2011

Hsp90 Orchestrates Transcriptional Regulation by Hsf1 and Cell Wall Remodelling by MAPK Signalling during Thermal Adaptation in a Pathogenic Yeast

por Leach, Michelle D., Budge, Susan, Walker, Louise, Munro, Carol, Cowen, Leah E., Brown, Alistair J. P.
Publicado 2012

Candida albicans Is Resistant to Polyglutamine Aggregation and Toxicity

por Leach, Michelle D., Kim, TaeHyung, DiGregorio, Sonja E., Collins, Cathy, Zhang, Zhaolei, Duennwald, Martin L., Cowen, Leah E.
Publicado 2016

Signaling through Lrg1, Rho1 and Pkc1 Governs Candida albicans Morphogenesis in Response to Diverse Cues

por Xie, Jinglin L., Grahl, Nora, Sless, Trevor, Leach, Michelle D., Kim, Sang Hu, Hogan, Deborah A., Robbins, Nicole, Cowen, Leah E.
Publicado 2016

Ydj1 governs fungal morphogenesis and stress response, and facilitates mitochondrial protein import via Mas1 and Mas2

por Xie, Jinglin L., Bohovych, Iryna, Wong, Erin O.Y., Lambert, Jean-Philippe, Gingras, Anne-Claude, Khalimonchuk, Oleh, Cowen, Leah E., Leach, Michelle D.
Publicado 2017

Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans

por Leach, Michelle D., Farrer, Rhys A., Tan, Kaeling, Miao, Zhengqiang, Walker, Louise A., Cuomo, Christina A., Wheeler, Robert T., Brown, Alistair J. P., Wong, Koon Ho, Cowen, Leah E.
Publicado 2016

The Evolutionary Rewiring of Ubiquitination Targets Has Reprogrammed the Regulation of Carbon Assimilation in the Pathogenic Yeast Candida albicans

por Sandai, Doblin, Yin, Zhikang, Selway, Laura, Stead, David, Walker, Janet, Leach, Michelle D., Bohovych, Iryna, Ene, Iuliana V., Kastora, Stavroula, Budge, Susan, Munro, Carol A., Odds, Frank C., Gow, Neil A. R., Brown, Alistair J. P.
Publicado 2012

Stress adaptation in a pathogenic fungus

por Brown, Alistair J. P., Budge, Susan, Kaloriti, Despoina, Tillmann, Anna, Jacobsen, Mette D., Yin, Zhikang, Ene, Iuliana V., Bohovych, Iryna, Sandai, Doblin, Kastora, Stavroula, Potrykus, Joanna, Ballou, Elizabeth R., Childers, Delma S., Shahana, Shahida, Leach, Michelle D.
Publicado 2014

Correction for Sandai et al., The Evolutionary Rewiring of Ubiquitination Targets Has Reprogrammed the Regulation of Carbon Assimilation in the Pathogenic Yeast Candida albicans

por Sandai, Doblin, Yin, Zhikang, Selway, Laura, Stead, David, Walker, Janet, Leach, Michelle D., Bohovych, Iryna, Ene, Iuliana V., Kastora, Stavroula, Budge, Susan, Munro, Carol A., Odds, Frank C., Gow, Neil A. R., Brown, Alistair J. P.
Publicado 2015

The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation

por Xie, Jinglin L., Qin, Longguang, Miao, Zhengqiang, Grys, Ben T., Diaz, Jacinto De La Cruz, Ting, Kenneth, Krieger, Jonathan R., Tong, Jiefei, Tan, Kaeling, Leach, Michelle D., Ketela, Troy, Moran, Michael F., Krysan, Damian J., Boone, Charles, Andrews, Brenda J., Selmecki, Anna, Ho Wong, Koon, Robbins, Nicole, Cowen, Leah E.
Publicado 2017