The biosynthetic pathway to ossamycin, a macrocyclic polyketide bearing a spiroacetal moiety

por Bilyk, Oksana, Samborskyy, Markiyan, Leadlay, Peter F.
Publicado 2019

Intermediates in monensin biosynthesis: A late step in biosynthesis of the polyether ionophore monensin is crucial for the integrity of cation binding

por Hüttel, Wolfgang, Spencer, Jonathan B, Leadlay, Peter F
Publicado 2014

The biosynthetic pathway to tetromadurin (SF2487/A80577), a polyether tetronate antibiotic

por Little, Rory F., Samborskyy, Markiyan, Leadlay, Peter F.
Publicado 2020

An Amidinohydrolase Provides the Missing Link in the Biosynthesis of Amino Marginolactone Antibiotics

por Hong, Hui, Samborskyy, Markiyan, Lindner, Frederick, Leadlay, Peter F.
Publicado 2015

A Novel Mycolactone Toxin Obtained by Biosynthetic Engineering

por Hong, Hui, Stinear, Tim, Porter, Jessica, Demangel, Caroline, Leadlay, Peter F
Publicado 2007

Sulfation and amidinohydrolysis in the biosynthesis of giant linear polyenes

por Hong, Hui, Samborskyy, Markiyan, Usachova, Katsiaryna, Schnatz, Katharina, Leadlay, Peter F
Publicado 2017

Mycolactones: immunosuppressive and cytotoxic polyketides produced by aquatic mycobacteria

por Hong, Hui, Demangel, Caroline, Pidot, Sacha J., Leadlay, Peter F., Stinear, Tim
Publicado 2008

Mycolactone Diffuses from Mycobacterium ulcerans–Infected Tissues and Targets Mononuclear Cells in Peripheral Blood and Lymphoid Organs

por Hong, Hui, Coutanceau, Emmanuelle, Leclerc, Marion, Caleechurn, Laxmee, Leadlay, Peter F., Demangel, Caroline
Publicado 2008

Macrodiolide Formation by the Thioesterase of a Modular Polyketide Synthase**

por Zhou, Yongjun, Prediger, Patrícia, Dias, Luiz Carlos, Murphy, Annabel C, Leadlay, Peter F
Publicado 2015

Macrodiolide Formation by the Thioesterase of a Modular Polyketide Synthase**

por Zhou, Yongjun, Prediger, Patrícia, Dias, Luiz Carlos, Murphy, Annabel C, Leadlay, Peter F
Publicado 2015

Evidence for an iterative module in chain elongation on the azalomycin polyketide synthase

por Hong, Hui, Sun, Yuhui, Zhou, Yongjun, Stephens, Emily, Samborskyy, Markiyan, Leadlay, Peter F
Publicado 2016

Site-Specific Modification of the Anticancer and Antituberculosis Polyether Salinomycin by Biosynthetic Engineering

por Luhavaya, Hanna, Williams, Simon R, Hong, Hui, Gonzaga de Oliveira, Luciana, Leadlay, Peter F
Publicado 2014

In vitro reconstruction of tetronate RK-682 biosynthesis

por Sun, Yuhui, Hahn, Frank, Demydchuk, Yuliya, Chettle, James, Tosin, Manuela, Osada, Hiroyuki, Leadlay, Peter F.
Publicado 2009

Iterative Mechanism of Macrodiolide Formation in the Anticancer Compound Conglobatin

por Zhou, Yongjun, Murphy, Annabel C., Samborskyy, Markiyan, Prediger, Patricia, Dias, Luiz Carlos, Leadlay, Peter F.
Publicado 2015

Chemical Probes for the Functionalization of Polyketide Intermediates**

por Riva, Elena, Wilkening, Ina, Gazzola, Silvia, Li, W M Ariel, Smith, Luke, Leadlay, Peter F, Tosin, Manuela
Publicado 2014

Enzymology of Pyran Ring A Formation in Salinomycin Biosynthesis

por Luhavaya, Hanna, Dias, Marcio V B, Williams, Simon R, Hong, Hui, de Oliveira, Luciana G, Leadlay, Peter F
Publicado 2015

Enzymology of Pyran Ring A Formation in Salinomycin Biosynthesis

por Luhavaya, Hanna, Dias, Marcio V. B., Williams, Simon R., Hong, Hui, de Oliveira, Luciana G., Leadlay, Peter F.
Publicado 2015

Structure of the Glycosyltransferase EryCIII in Complex with its Activating P450 Homologue EryCII

por Moncrieffe, Martin C., Fernandez, Maria-Jose, Spiteller, Dieter, Matsumura, Hiroyoshi, Gay, Nicholas J., Luisi, Ben F., Leadlay, Peter F.
Publicado 2012

Specificity and Promiscuity at the Branch Point in Gentamicin Biosynthesis

por Guo, Junhong, Huang, Fanglu, Huang, Chuan, Duan, Xiaobo, Jian, Xinyun, Leeper, Finian, Deng, Zixin, Leadlay, Peter F., Sun, Yuhui
Publicado 2014

Delineating the Biosynthesis of Gentamicin X2, the Common Precursor of the Gentamicin C Antibiotic Complex

por Huang, Chuan, Huang, Fanglu, Moison, Eileen, Guo, Junhong, Jian, Xinyun, Duan, Xiaobo, Deng, Zixin, Leadlay, Peter F., Sun, Yuhui
Publicado 2015