Oxidation of Low-Density Lipoprotein by Iron at Lysosomal pH: Implications for Atherosclerosis

por Satchell, Leanne, Leake, David S.
Publicado 2012

Antioxidants inhibit low density lipoprotein oxidation less at lysosomal pH: A possible explanation as to why the clinical trials of antioxidants might have failed

por Ahmad, Feroz, Leake, David S.
Publicado 2018

Lysosomal oxidation of LDL alters lysosomal pH, induces senescence, and increases secretion of pro-inflammatory cytokines in human macrophages

por Ahmad, Feroz, Leake, David S.
Publicado 2019

Intelligent information processing iv: 5th IFIP international conference on intelligent information processing, October 19-22, 2008, Beijing, China

por Mercier-Laurent, Eunikka, Leake, David
Publicado 2008

Intelligent information processing vii: 8th IFIP TC 12 international conference, IIP 2014, Hangzhou, China, October 17-20, 2014, proceedings

por Shi, Zhongzhi, Wu, Zhaohui, Leake, David, Sattler, Uli
Publicado 2014

Cysteamine inhibits lysosomal oxidation of low density lipoprotein in human macrophages and reduces atherosclerosis in mice

por Wen, Yichuan, Ahmad, Feroz, Mohri, Zahra, Weinberg, Peter D., Leake, David S.
Publicado 2019

The synthetic glycolipid-based TLR4 antagonist FP7 negatively regulates in vitro and in vivo haematopoietic and non-haematopoietic vascular TLR4 signalling

por Palmer, Charys, Peri, Francesco, Neumann, Frank, Ahmad, Feroz, Leake, David S., Pirianov, Grisha
Publicado 2018

Workplace inequality is associated with status-signaling expenditure

por Muggleton, Naomi, Trendl, Anna, Walasek, Lukasz, Leake, David, Gathergood, John, Stewart, Neil
Publicado 2022

Monocytic Cell Adhesion to Oxidised Ligands: Relevance to Cardiovascular Disease

por Poston, Robin N., Chughtai, Jenna, Ujkaj, Desara, Louis, Huguette, Leake, David S., Cooper, Dianne
Publicado 2022

Cysteamine Decreases Low‐Density Lipoprotein Oxidation, Causes Regression of Atherosclerosis, and Improves Liver and Muscle Function in Low‐Density Lipoprotein Receptor–Deficient M...

por Ahmad, Feroz, Mitchell, Robert D., Houben, Tom, Palo, Angela, Yadati, Tulasi, Parnell, Andrew J., Patel, Ketan, Shiri‐Sverdlov, Ronit, Leake, David S.
Publicado 2021

Pro-Inflammatory Implications of 2-Hydroxypropyl-β-cyclodextrin Treatment

por Houben, Tom, Yadati, Tulasi, de Kruijf, Robbin, Gijbels, Marion J. J., Luiken, Joost J. F. P., van Zandvoort, Marc, Kapsokalyvas, Dimitris, Lütjohann, Dieter, Westerterp, Marit, Plat, Jogchum, Leake, David, Shiri-Sverdlov, Ronit
Publicado 2021