Senolytic vaccination: a new mandate for cardiovascular health?

por Lear, Travis B., Finkel, Toren
Publicado 2022

The Human IL-22 Receptor Is Regulated through the Action of the Novel E3 Ligase Subunit FBXW12, Which Functions as an Epithelial Growth Suppressor

por Franz, Joseph, Jerome, Jacob, Lear, Travis, Gong, Qiaoke, Weathington, Nathaniel M.
Publicado 2015

Novel PDE4 Inhibitors Derived from Chinese Medicine Forsythia

por Coon, Tiffany A., McKelvey, Alison C., Weathington, Nate M., Birru, Rahel L., Lear, Travis, Leikauf, George D., Chen, Bill B.
Publicado 2014

A small molecule NRF2 activator BC-1901S ameliorates inflammation through DCAF1/NRF2 axis

por Chen, Yanwen, Evankovich, John W., Lear, Travis B., Tuncer, Ferhan, Kennerdell, Jason R., Camarco, Daniel P., Shishido, Morgan S., Liu, Yuan, Chen, Bill B.
Publicado 2020

A Repurposed Drug Screen for Compounds Regulating Aquaporin 5 Stability in Lung Epithelial Cells

por Villandre, John, White, Virginia, Lear, Travis B., Chen, Yanwen, Tuncer, Ferhan, Vaiz, Emily, Tuncer, Beyza, Lockwood, Karina, Camarco, Dan, Liu, Yuan, Chen, Bill B., Evankovich, John
Publicado 2022

E3 ubiquitin ligase ZBTB25 suppresses beta coronavirus infection through ubiquitination of the main viral protease MPro

por Lear, Travis B., Boudreau, Áine N., Lockwood, Karina C., Chu, Elise, Camarco, Daniel P., Cao, Qing, Nguyen, Matthew, Evankovich, John W., Finkel, Toren, Liu, Yuan, Chen, Bill B.
Publicado 2023

RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunity

por McKelvey, Alison C, Lear, Travis B, Dunn, Sarah R, Evankovich, John, Londino, James D, Bednash, Joseph S, Zhang, Yingze, McVerry, Bryan J, Liu, Yuan, Chen, Bill B
Publicado 2016

Ubiquitin E3 ligase FIEL1 regulates fibrotic lung injury through SUMO-E3 ligase PIAS4

por Lear, Travis, McKelvey, Alison C., Rajbhandari, Shristi, Dunn, Sarah R., Coon, Tiffany A., Connelly, William, Zhao, Joe Y., Kass, Daniel J., Zhang, Yingze, Liu, Yuan, Chen, Bill B.
Publicado 2016

Modulation of lysosomal function as a therapeutic approach for coronaviral infections

por Liu, Yuan, Lear, Travis, Larsen, Mads, Lin, Bo, Cao, Qing, Alfaras, Irene, Kennerdell, Jason, Salminen, Laura, Camarco, Daniel, Lockwood, Karina, Ma, Jing, Liu, Jie, Tan, Jay, Myerburg, Michael, Chen, Yanwen, St Croix, Claudette, Sekine, Yusuke, Evankovich, John, Finkel, Toren, Chen, Bill
Publicado 2021

A high throughput screen for TMPRSS2 expression identifies FDA-approved and clinically advanced compounds that can limit SARS-CoV-2 entry

por Chen, Yanwen, Lear, Travis B., Evankovich, John W., Larsen, Mads B., Lin, Bo, Alfaras, Irene, Kennerdell, Jason R., Salminen, Laura, Camarco, Daniel P., Lockwood, Karina C., Liu, Jie, Myerburg, Michael M., McDyer, John F., Liu, Yuan, Finkel, Toren, Chen, Bill B.
Publicado 2020

A Fbxo48 inhibitor prevents pAMPKα degradation and ameliorates insulin resistance

por Liu, Yuan, Jurczak, Michael J., Lear, Travis B., Lin, Bo, Larsen, Mads B., Kennerdell, Jason R., Chen, Yanwen, Huckestein, Brydie R., Nguyen, Matthew K., Tuncer, Ferhan, Jiang, Yu, Monga, Satdarshan P., O’Donnell, Christopher P., Finkel, Toren, Chen, Bill B., Mallampalli, Rama K.
Publicado 2021

A high-throughput screen for TMPRSS2 expression identifies FDA-approved compounds that can limit SARS-CoV-2 entry

por Chen, Yanwen, Lear, Travis B., Evankovich, John W., Larsen, Mads B., Lin, Bo, Alfaras, Irene, Kennerdell, Jason R., Salminen, Laura, Camarco, Daniel P., Lockwood, Karina C., Tuncer, Ferhan, Liu, Jie, Myerburg, Michael M., McDyer, John F., Liu, Yuan, Finkel, Toren, Chen, Bill B.
Publicado 2021

E3 Ligase Subunit Fbxo15 and PINK1 Kinase Regulate Cardiolipin Synthase 1 Stability and Mitochondrial Function in Pneumonia

por Chen, Bill B., Coon, Tiffany A., Glasser, Jennifer R., Zou, Chunbin, Ellis, Bryon, Das, Tuhin, McKelvey, Alison C., Rajbhandari, Shristi, Lear, Travis, Kamga, Christelle, Shiva, Sruti, Li, Chenjian, Pilewski, Joseph M., Callio, Jason, Chu, Charleen T., Ray, Anuradha, Ray, Prabir, Tyurina, Yulia Y., Kagan, Valerian E., Mallampalli, Rama K.
Publicado 2014