Polymerase II Promoter Strength Determines Efficacy of microRNA Adapted shRNAs

por Lebbink, Robert Jan, Lowe, Maggie, Chan, Theresa, Khine, Htet, Wang, Xiaoyin, McManus, Michael T.
Publicado 2011

Comprehensive profiling of functional Epstein-Barr virus miRNA expression in human cell lines

por Hooykaas, Marjolein J. G., Kruse, Elisabeth, Wiertz, Emmanuel J. H. J., Lebbink, Robert Jan
Publicado 2016

A systematic review on global RSV genetic data: Identification of knowledge gaps

por Langedijk, Annefleur C., Harding, Eline R., Konya, Burak, Vrancken, Bram, Lebbink, Robert Jan, Evers, Anouk, Willemsen, Joukje, Lemey, Philippe, Bont, Louis J.
Publicado 2021

The E3 Ubiquitin Ligase TMEM129 Is a Tri-Spanning Transmembrane Protein

por van de Weijer, Michael L., van Muijlwijk, Guus H., Visser, Linda J., Costa, Ana I., Wiertz, Emmanuel J. H. J., Lebbink, Robert Jan
Publicado 2016

Rapid Creation and Quantitative Monitoring of High Coverage shRNA Libraries

por Bassik, Michael C., Lebbink, Robert Jan, Churchman, L. Stirling, Ingolia, Nicholas T., Patena, Weronika, LeProust, Emily M., Schuldiner, Maya, Weissman, Jonathan S., McManus, Michael T.
Publicado 2009

A combinational CRISPR/Cas9 gene-editing approach can halt HIV replication and prevent viral escape

por Lebbink, Robert Jan, de Jong, Dorien C. M., Wolters, Femke, Kruse, Elisabeth M., van Ham, Petra M., Wiertz, Emmanuel J. H. J., Nijhuis, Monique
Publicado 2017

Mutagenesis of the Varicella-Zoster Virus Genome Demonstrates That VLT and VLT-ORF63 Proteins Are Dispensable for Lytic Infection

por Braspenning, Shirley E., Lebbink, Robert Jan, Depledge, Daniel P., Schapendonk, Claudia M. E., Anderson, Laura A., Verjans, Georges M. G. M., Sadaoka, Tomohiko, Ouwendijk, Werner J. D.
Publicado 2021

Collagens are functional, high affinity ligands for the inhibitory immune receptor LAIR-1

por Lebbink, Robert Jan, de Ruiter, Talitha, Adelmeijer, Jelle, Brenkman, Arjan B., van Helvoort, Joop M., Koch, Manuel, Farndale, Richard W., Lisman, Ton, Sonnenberg, Arnoud, Lenting, Peter J., Meyaard, Linde
Publicado 2006

Impaired proteolysis by SPPL2a causes CD74 fragment accumulation that can be recognized by anti‐CD74 autoantibodies in human ankylosing spondylitis

por van Kempen, Tessa S., Leijten, Emmerik F.A., Lindenbergh, Marthe F.S., Nordkamp, Michel Olde, Driessen, Christoph, Lebbink, Robert‐Jan, Baerlecken, Niklas, Witte, Torsten, Radstake, Timothy R.D.J., Boes, Marianne
Publicado 2020

Global Molecular Epidemiology of Respiratory Syncytial Virus from the 2017−2018 INFORM-RSV Study

por Tabor, David E., Fernandes, Fiona, Langedijk, Annefleur C., Wilkins, Deidre, Lebbink, Robert Jan, Tovchigrechko, Andrey, Ruzin, Alexey, Kragten-Tabatabaie, Leyla, Jin, Hong, Esser, Mark T., Bont, Louis J., Abram, Michael E.
Publicado 2020

Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex

por van de Weijer, Michael L., Krshnan, Logesvaran, Liberatori, Sabrina, Guerrero, Elena Navarro, Robson-Tull, Jacob, Hahn, Lilli, Lebbink, Robert Jan, Wiertz, Emmanuel J.H.J., Fischer, Roman, Ebner, Daniel, Carvalho, Pedro
Publicado 2020

Quality Control of ER Membrane Proteins by the RNF185/Membralin Ubiquitin Ligase Complex

por van de Weijer, Michael L., Krshnan, Logesvaran, Liberatori, Sabrina, Guerrero, Elena Navarro, Robson-Tull, Jacob, Hahn, Lilli, Lebbink, Robert Jan, Wiertz, Emmanuel J.H.J., Fischer, Roman, Ebner, Daniel, Carvalho, Pedro
Publicado 2020

Novel chimerized IgA CD20 antibodies: Improving neutrophil activation against CD20-positive malignancies

por Evers, Mitchell, Ten Broeke, Toine, Jansen, J.H. Marco, Nederend, Maaike, Hamdan, Firas, Reiding, Karli R., Meyer, Saskia, Moerer, Petra, Brinkman, Iris, Rösner, Thies, Lebbink, Robert Jan, Valerius, Thomas, Leusen, Jeanette H.W.
Publicado 2020

CRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent Infections

por van Diemen, Ferdy R., Kruse, Elisabeth M., Hooykaas, Marjolein J. G., Bruggeling, Carlijn E., Schürch, Anita C., van Ham, Petra M., Imhof, Saskia M., Nijhuis, Monique, Wiertz, Emmanuel J. H. J., Lebbink, Robert Jan
Publicado 2016

Importin α1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons

por Döhner, Katinka, Ramos-Nascimento, Ana, Bialy, Dagmara, Anderson, Fenja, Hickford-Martinez, Ana, Rother, Franziska, Koithan, Thalea, Rudolph, Kathrin, Buch, Anna, Prank, Ute, Binz, Anne, Hügel, Stefanie, Lebbink, Robert Jan, Hoeben, Rob C., Hartmann, Enno, Bader, Michael, Bauerfeind, Rudolf, Sodeik, Beate
Publicado 2018

Proteasomal Degradation of Proinsulin Requires Derlin-2, HRD1 and p97

por Hoelen, Hanneke, Zaldumbide, Arnaud, van Leeuwen, Wouter F., Torfs, Ellen C. W., Engelse, Marten A., Hassan, Chopie, Lebbink, Robert Jan, de Koning, Eelco J., Resssing, Maaike E., de Ru, Arnoud H., van Veelen, Peter A., Hoeben, Rob C., Roep, Bart O., Wiertz, Emmanuel J. H. J.
Publicado 2015

Host–Receptor Post-Translational Modifications Refine Staphylococcal Leukocidin Cytotoxicity

por Tromp, Angelino T., Van Gent, Michiel, Jansen, Joris P., Scheepmaker, Lisette M., Velthuizen, Anneroos, De Haas, Carla J.C., Van Kessel, Kok P.M., Bardoel, Bart W., Boettcher, Michael, McManus, Michael T., Van Strijp, Jos A.G., Lebbink, Robert Jan, Haas, Pieter-Jan A., Spaan, András N.
Publicado 2020

A high-coverage shRNA screen identifies TMEM129 as an E3 ligase involved in ER-associated protein degradation

por van de Weijer, Michael L., Bassik, Michael C., Luteijn, Rutger D., Voorburg, Cornelia M., Lohuis, Mirjam A.M., Kremmer, Elisabeth, Hoeben, Rob C., LeProust, Emily M., Chen, Siyuan, Hoelen, Hanneke, Ressing, Maaike E., Patena, Weronika, Weissman, Jonathan S., McManus, Michael T., Wiertz, Emmanuel J.H.J., Lebbink, Robert Jan
Publicado 2014

In-depth Characterization of Vaccine Breakthrough Infections With SARS-CoV-2 Among Health Care Workers in a Dutch Academic Medical Center

por Rümke, Lidewij W, Groenveld, Femke C, van Os, Yvonne M G, Praest, Patrique, Tanja, Anniek A N, de Jong, Dorien T C M, Symons, Jori, Schuurman, Rob, Reinders, Tessa, Hofstra, L Marije, Nierkens, Stefan, Thijsen, Steven F T, Heron, Michiel, Lebbink, Robert-Jan, Beekman, Jeffrey M, Nijhuis, Monique, Wensing, Annemarie M J
Publicado 2021

The Epstein-Barr Virus Glycoprotein gp150 Forms an Immune-Evasive Glycan Shield at the Surface of Infected Cells

por Gram, Anna M., Oosenbrug, Timo, Lindenbergh, Marthe F. S., Büll, Christian, Comvalius, Anouskha, Dickson, Kathryn J. I., Wiegant, Joop, Vrolijk, Hans, Lebbink, Robert Jan, Wolterbeek, Ron, Adema, Gosse J., Griffioen, Marieke, Heemskerk, Mirjam H. M., Tscharke, David C., Hutt-Fletcher, Lindsey M., Wiertz, Emmanuel J. H. J., Hoeben, Rob C., Ressing, Maaike E.
Publicado 2016