Crystal structure of ethyl 2-methyl-5,10-dioxo-4-phenyl-5,10-di­hydro-4H-11-thia-1,4a-di­aza­benzo[b]fluorene-3-carb­oxy­late

por Yartsev, Yegor, Lyubashov, Pavel, Povstyanoy, Vyacheslav, Povstyaniy, Mykhailo, Lebedyeva, Iryna
Publicado 2018

Ethyl 1,6-dimethyl-2-oxo-4-(quinolin-4-yl)-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate

por Zubatyuk, Roman I., Shishkin, Oleg V., Ihmels, Heiko, Lebedyeva, Iryna A., Povstyanoy, Mykhaylo V.
Publicado 2010

Multi-kinase inhibitors interact with sildenafil and ERBB1/2/4 inhibitors to kill tumor cells in vitro and in vivo

por Booth, Laurence, Albers, Thomas, Roberts, Jane L., Tavallai, Mehrad, Poklepovic, Andrew, Lebedyeva, Iryna O., Dent, Paul
Publicado 2016

Ceramide mediates FasL-induced caspase 8 activation in colon carcinoma cells to enhance FasL-induced cytotoxicity by tumor-specific cytotoxic T lymphocytes

por Coe, Genevieve L., Redd, Priscilla S., Paschall, Amy V., Lu, Chunwan, Gu, Lilly, Cai, Houjian, Albers, Thomas, Lebedyeva, Iryna O., Liu, Kebin
Publicado 2016

Ceramide activates lysosomal cathepsin B and cathepsin D to attenuate autophagy and induces ER stress to suppress myeloid-derived suppressor cells

por Liu, Feiyan, Li, Xia, Lu, Chunwan, Bai, Aiping, Bielawski, Jacek, Bielawska, Alicja, Marshall, Brendan, Schoenlein, Patricia V., Lebedyeva, Iryna O., Liu, Kebin
Publicado 2016

Changes in the tumor microenvironment and outcome for TME-targeting therapy in glioblastoma: A pilot study

por Ali, Sehar, Borin, Thaiz F., Piranlioglu, Raziye, Ara, Roxan, Lebedyeva, Iryna, Angara, Kartik, Achyut, Bhagelu R., Arbab, Ali Syed, Rashid, Mohammad H.
Publicado 2021

A Non-Systemic Phosphodiesterase-5 Inhibitor Suppresses Colon Proliferation in Mice

por Lee, Avelina, Lebedyeva, Iryna, Zhi, Wenbo, Senthil, Vani, Cheema, Herjot, Brands, Michael W., Bush, Weston, Lambert, Nevin A., Snipes, Madeline, Browning, Darren D.
Publicado 2023

Targeting TREM1 augments antitumor T cell immunity by inhibiting myeloid-derived suppressor cells and restraining anti–PD-1 resistance

por Ajith, Ashwin, Mamouni, Kenza, Horuzsko, Daniel D., Musa, Abu, Dzutsev, Amiran K., Fang, Jennifer R., Chadli, Ahmed, Zhu, Xingguo, Lebedyeva, Iryna, Trinchieri, Giorgio, Horuzsko, Anatolij
Publicado 2023

HET0016 decreases lung metastasis from breast cancer in immune-competent mouse model

por Borin, Thaiz F., Shankar, Adarsh, Angara, Kartik, Rashid, Mohammad H., Jain, Meenu, Iskander, Asm, Ara, Roxan, Lebedyeva, Iryna, Korkaya, Hasan, Achyut, Bhagelu R., Arbab, Ali S.
Publicado 2017

CXCR2-Expressing Tumor Cells Drive Vascular Mimicry in Antiangiogenic Therapy–Resistant Glioblastoma

por Angara, Kartik, Borin, Thaiz F., Rashid, Mohammad H., Lebedyeva, Iryna, Ara, Roxan, Lin, Ping-Chang, Iskander, ASM, Bollag, Roni J., Achyut, Bhagelu R., Arbab, Ali S.
Publicado 2018

Sweet-Tasting Ionic Conjugates of Local Anesthetics and Vasoconstrictors

por Neubert, John K., Oliferenko, Alexander A., Oliferenko, Polina V., Emets, Sergey V., Ostrov, David A., Altschuler, Gary I., Calkins, Joe, Wickersham, Jay, Hromas, Robert, Lebedyeva, Iryna O.
Publicado 2021

Multi-kinase inhibitors can associate with heat shock proteins through their NH(2)-termini by which they suppress chaperone function

por Booth, Laurence, Shuch, Brian, Albers, Thomas, Roberts, Jane L., Tavallai, Mehrad, Proniuk, Stefan, Zukiwski, Alexander, Wang, Dasheng, Chen, Ching-Shih, Bottaro, Don, Ecroyd, Heath, Lebedyeva, Iryna O., Dent, Paul
Publicado 2016

Intravenous Formulation of HET0016 Decreased Human Glioblastoma Growth and Implicated Survival Benefit in Rat Xenograft Models

por Jain, Meenu, Gamage, Nipuni-Dhanesha H., Alsulami, Meshal, Shankar, Adarsh, Achyut, Bhagelu R., Angara, Kartik, Rashid, Mohammad H., Iskander, Asm, Borin, Thaiz F., Wenbo, Zhi, Ara, Roxan, Ali, Meser M., Lebedyeva, Iryna, Chwang, Wilson B., Guo, Austin, Bagher-Ebadian, Hassan, Arbab, Ali S.
Publicado 2017