R-spondins can potentiate WNT signaling without LGRs

por Lebensohn, Andres M, Rohatgi, Rajat
Publicado 2018

Discovery of gene regulatory elements through a new bioinformatics analysis of haploid genetic screens

por Patel, Bhaven B., Lebensohn, Andres M., Pusapati, Ganesh V., Carette, Jan E., Salzman, Julia, Rohatgi, Rajat
Publicado 2019

Oxysterol derivatives Oxy186 and Oxy210 inhibit WNT signaling in non-small cell lung cancer

por Tang, Liu-Ya, Spezia, Marie, Chen, Ting, Shin, Jee-Hye, Wang, Feng, Stappenbeck, Frank, Lebensohn, Andres M., Parhami, Farhad, Zhang, Ying E.
Publicado 2022

Direct ionic stress sensing and mitigation by the transcription factor NFAT5

por Khandwala, Chandni B., Sarkar, Parijat, Schmidt, H. Broder, Ma, Mengxiao, Kinnebrew, Maia, Pusapati, Ganesh V., Patel, Bhaven B., Tillo, Desiree, Lebensohn, Andres M., Rohatgi, Rajat
Publicado 2023

R-spondins engage heparan sulfate proteoglycans to potentiate WNT signaling

por Dubey, Ramin, van Kerkhof, Peter, Jordens, Ingrid, Malinauskas, Tomas, Pusapati, Ganesh V, McKenna, Joseph K, Li, Dan, Carette, Jan E, Ho, Mitchell, Siebold, Christian, Maurice, Madelon, Lebensohn, Andres M, Rohatgi, Rajat
Publicado 2020

Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling

por Lebensohn, Andres M, Dubey, Ramin, Neitzel, Leif R, Tacchelly-Benites, Ofelia, Yang, Eungi, Marceau, Caleb D, Davis, Eric M, Patel, Bhaven B, Bahrami-Nejad, Zahra, Travaglini, Kyle J, Ahmed, Yashi, Lee, Ethan, Carette, Jan E, Rohatgi, Rajat
Publicado 2016

The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6

por Spencer, Zachary T., Ng, Victoria H., Benchabane, Hassina, Siddiqui, Ghalia Saad, Duwadi, Deepesh, Maines, Ben, Bryant, Jamal M., Schwarzkopf, Anna, Yuan, Kai, Kassel, Sara N., Mishra, Anant, Pimentel, Ashley, Lebensohn, Andres M., Rohatgi, Rajat, Gerber, Scott A., Robbins, David J., Lee, Ethan, Ahmed, Yashi
Publicado 2023

The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling

por Ng, Victoria H., Spencer, Zachary, Neitzel, Leif R., Nayak, Anmada, Loberg, Matthew A., Shen, Chen, Kassel, Sara N., Kroh, Heather K., An, Zhenyi, Anthony, Christin C., Bryant, Jamal M., Lawson, Amanda, Goldsmith, Lily, Benchabane, Hassina, Hansen, Amanda G., Li, Jingjing, D’Souza, Starina, Lebensohn, Andres M., Rohatgi, Rajat, Weiss, William A., Weiss, Vivian L., Williams, Charles, Hong, Charles C., Robbins, David J., Ahmed, Yashi, Lee, Ethan
Publicado 2023