Human Adenosine A(2A) Receptor: Molecular Mechanism of Ligand Binding and Activation

por Carpenter, Byron, Lebon, Guillaume
Publicado 2017

Pi sampling: a methodical and flexible approach to initial macromolecular crystallization screening

por Gorrec, Fabrice, Palmer, Colin M., Lebon, Guillaume, Warne, Tony
Publicado 2011

Thermostabilisation of an Agonist-Bound Conformation of the Human Adenosine A(2A) Receptor

por Lebon, Guillaume, Bennett, Kirstie, Jazayeri, Ali, Tate, Christopher G.
Publicado 2011

Agonist-bound adenosine A(2A) receptor structures reveal common features of GPCR activation

por Lebon, Guillaume, Warne, Tony, Edwards, Patricia C., Bennett, Kirstie, Langmead, Christopher J., Leslie, Andrew G.W., Tate, Christopher G.
Publicado 2011

Direct coupling of detergent purified human mGlu(5) receptor to the heterotrimeric G proteins Gq and Gs

por Nasrallah, Chady, Rottier, Karine, Marcellin, Romain, Compan, Vincent, Font, Joan, Llebaria, Amadeu, Pin, Jean-Philippe, Banères, Jean-Louis, Lebon, Guillaume
Publicado 2018

Structure-Based Discovery of Negative Allosteric Modulators of the Metabotropic Glutamate Receptor 5

por Kampen, Stefanie, Rodríguez, David, Jørgensen, Morten, Kruszyk-Kujawa, Monika, Huang, Xinyan, Collins, Michael, Boyle, Noel, Maurel, Damien, Rudling, Axel, Lebon, Guillaume, Carlsson, Jens
Publicado 2022

Outrunning free radicals in room-temperature macromolecular crystallography

por Owen, Robin L., Axford, Danny, Nettleship, Joanne E., Owens, Raymond J., Robinson, James I., Morgan, Ann W., Doré, Andrew S., Lebon, Guillaume, Tate, Christopher G., Fry, Elizabeth E., Ren, Jingshan, Stuart, David I., Evans, Gwyndaf
Publicado 2012

A Bacterial Toxin with Analgesic Properties: Hyperpolarization of DRG Neurons by Mycolactone

por Song, Ok-Ryul, Kim, Han-Byul, Jouny, Samuel, Ricard, Isabelle, Vandeputte, Alexandre, Deboosere, Nathalie, Marion, Estelle, Queval, Christophe J., Lesport, Pierre, Bourinet, Emmanuel, Henrion, Daniel, Oh, Seog Bae, Lebon, Guillaume, Sandoz, Guillaume, Yeramian, Edouard, Marsollier, Laurent, Brodin, Priscille
Publicado 2017

Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations

por Nasrallah, Chady, Cannone, Giuseppe, Briot, Julie, Rottier, Karine, Berizzi, Alice E., Huang, Chia-Ying, Quast, Robert B., Hoh, Francois, Banères, Jean-Louis, Malhaire, Fanny, Berto, Ludovic, Dumazer, Anaëlle, Font-Ingles, Joan, Gómez-Santacana, Xavier, Catena, Juanlo, Kniazeff, Julie, Goudet, Cyril, Llebaria, Amadeu, Pin, Jean-Philippe, Vinothkumar, Kutti R., Lebon, Guillaume
Publicado 2021

Inhibition of the angiotensin II type 2 receptor AT(2)R is a novel therapeutic strategy for glioblastoma

por Perryman, Richard, Renziehausen, Alexander, Shaye, Hamidreza, Kostagianni, Androniki D., Tsiailanis, Antonis D., Thorne, Thomas, Chatziathanasiadou, Maria V., Sivolapenko, Gregory B., El Mubarak, Mohamed Ahmed, Han, Gye Won, Zarzycka, Barbara, Katritch, Vsevolod, Lebon, Guillaume, Lo Nigro, Cristiana, Lattanzio, Laura, Morse, Sophie V., Choi, James J., O’Neill, Kevin, Kanaki, Zoi, Klinakis, Apostolos, Crook, Tim, Cherezov, Vadim, Tzakos, Andreas G., Syed, Nelofer
Publicado 2022