Differential Effects of CORM-2 and CORM-401 in Murine Intestinal Epithelial MODE-K Cells under Oxidative Stress

por Babu, Dinesh, Leclercq, Georges, Motterlini, Roberto, Lefebvre, Romain A.
Publicado 2017

Conventional and Computational Flow Cytometry Analyses Reveal Sustained Human Intrathymic T Cell Development From Birth Until Puberty

por Lavaert, Marieke, Valcke, Brecht, Vandekerckhove, Bart, Leclercq, Georges, Liang, Kai Ling, Taghon, Tom
Publicado 2020

Activation by SLAM Family Receptors Contributes to NK Cell Mediated “Missing-Self” Recognition

por Alari-Pahissa, Elisenda, Grandclément, Camille, Jeevan-Raj, Beena, Leclercq, Georges, Veillette, André, Held, Werner
Publicado 2016

IL-15 Augments TCR-Induced CD4(+) T Cell Expansion In Vitro by Inhibiting the Suppressive Function of CD25(High) CD4(+) T Cells

por Van Belle, Tom L., Dooms, Hans, Boonefaes, Tom, Wei, Xiao-Qing, Leclercq, Georges, Grooten, Johan
Publicado 2012

T-BET drives the conversion of human type 3 innate lymphoid cells into functional NK cells

por Kiekens, Laura, Wahlen, Sigrid, Persyn, Eva, De Vos, Zenzi, Taghon, Tom, Vandekerckhove, Bart, Leclercq, Georges
Publicado 2022

Type I interferon drives tumor necrosis factor–induced lethal shock

por Huys, Liesbeth, Van Hauwermeiren, Filip, Dejager, Lien, Dejonckheere, Eline, Lienenklaus, Stefan, Weiss, Siegfried, Leclercq, Georges, Libert, Claude
Publicado 2009

Defective CD4(+)CD25(+ )regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-γ

por Kelchtermans, Hilde, De Klerck, Bert, Mitera, Tania, Van Balen, Maarten, Bullens, Dominique, Billiau, Alfons, Leclercq, Georges, Matthys, Patrick
Publicado 2005

Host protective ASP-based vaccine against the parasitic nematode Ostertagia ostertagi triggers NK cell activation and mixed IgG1-IgG2 response

por González-Hernández, Ana, Van Coppernolle, Stefanie, Borloo, Jimmy, Van Meulder, Frederik, Paerewijck, Oonagh, Peelaers, Iris, Leclercq, Georges, Claerebout, Edwin, Geldhof, Peter
Publicado 2016

T-cells with a single tumor antigen-specific T-cell receptor can be generated in vitro from clinically relevant stem cell sources

por Bonte, Sarah, De Munter, Stijn, Goetgeluk, Glenn, Ingels, Joline, Pille, Melissa, Billiet, Lore, Taghon, Tom, Leclercq, Georges, Vandekerckhove, Bart, Kerre, Tessa
Publicado 2020

HES1 and HES4 have non-redundant roles downstream of Notch during early human T-cell development

por De Decker, Matthias, Lavaert, Marieke, Roels, Juliette, Tilleman, Laurentijn, Vandekerckhove, Bart, Leclercq, Georges, Van Nieuwerburgh, Filip, Van Vlierberghe, Pieter, Taghon, Tom
Publicado 2020

Transcriptional dynamics and epigenetic regulation of E and ID protein encoding genes during human T cell development

por Roels, Juliette, Van Hulle, Jolien, Lavaert, Marieke, Kuchmiy, Anna, Strubbe, Steven, Putteman, Tom, Vandekerckhove, Bart, Leclercq, Georges, Van Nieuwerburgh, Filip, Boehme, Lena, Taghon, Tom
Publicado 2022

Expression of the inhibitory Ly49E receptor is not critically involved in the immune response against cutaneous, pulmonary or liver tumours

por Filtjens, Jessica, Keirsse, Jiri, Van Ammel, Els, Taveirne, Sylvie, Van Acker, Aline, Kerre, Tessa, Taghon, Tom, Vandekerckhove, Bart, Plum, Jean, Van Ginderachter, Jo A., Leclercq, Georges
Publicado 2016

A Novel Non-Coding Variant in DCLRE1C Results in Deregulated Splicing and Induces SCID Through the Generation of a Truncated ARTEMIS Protein That Fails to Support V(D)J Recombinati...

por Strubbe, Steven, De Bruyne, Marieke, Pannicke, Ulrich, Beyls, Elien, Vandekerckhove, Bart, Leclercq, Georges, De Baere, Elfride, Bordon, Victoria, Vral, Anne, Schwarz, Klaus, Haerynck, Filomeen, Taghon, Tom
Publicado 2021

TXNIP Promotes Human NK Cell Development but Is Dispensable for NK Cell Functionality

por Persyn, Eva, Wahlen, Sigrid, Kiekens, Laura, Taveirne, Sylvie, Van Loocke, Wouter, Van Ammel, Els, Van Nieuwerburgh, Filip, Taghon, Tom, Vandekerckhove, Bart, Van Vlierberghe, Pieter, Leclercq, Georges
Publicado 2022

Ly49E Expression on CD8αα-Expressing Intestinal Intraepithelial Lymphocytes Plays No Detectable Role in the Development and Progression of Experimentally Induced Inflammatory Bowel...

por Van Acker, Aline, Filtjens, Jessica, Van Welden, Sophie, Taveirne, Sylvie, Van Ammel, Els, Vanhees, Mandy, Devisscher, Lindsey, Kerre, Tessa, Taghon, Tom, Vandekerckhove, Bart, Plum, Jean, Leclercq, Georges
Publicado 2014

The Ly49E Receptor Inhibits the Immune Control of Acute Trypanosoma cruzi Infection

por Filtjens, Jessica, Coltel, Nicolas, Cencig, Sabrina, Taveirne, Sylvie, Van Ammel, Els, Van Acker, Aline, Kerre, Tessa, Matthys, Patrick, Taghon, Tom, Vandekerckhove, Bart, Carlier, Yves, Truyens, Carine, Leclercq, Georges
Publicado 2016

In vitro OP9-DL1 co-culture and subsequent maturation in the presence of IL-21 generates tumor antigen-specific T cells with a favorable less-differentiated phenotype and enhanced...

por Bonte, Sarah, de Munter, Stijn, Billiet, Lore, Goetgeluk, Glenn, Ingels, Joline, Jansen, Hanne, Pille, Melissa, de Cock, Laurenz, Weening, Karin, Taghon, Tom, Leclercq, Georges, Vandekerckhove, Bart, Kerre, Tessa
Publicado 2021

Contribution of the Ly49E Natural Killer Receptor in the Immune Response to Plasmodium berghei Infection and Control of Hepatic Parasite Development

por Filtjens, Jessica, Foquet, Lander, Taveirne, Sylvie, Van Ammel, Els, Vanhees, Mandy, Van Acker, Aline, Kerre, Tessa, Taghon, Tom, Vandekerckhove, Bart, Plum, Jean, Van den Steen, Philippe E., Leclercq, Georges
Publicado 2014

NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20

por Drennan, Michael B., Govindarajan, Srinath, Verheugen, Eveline, Coquet, Jonathan M., Staal, Jens, McGuire, Conor, Taghon, Tom, Leclercq, Georges, Beyaert, Rudi, van Loo, Geert, Lambrecht, Bart N., Elewaut, Dirk
Publicado 2016

Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities

por Van Caeneghem, Yasmine, De Munter, Stijn, Tieppo, Paola, Goetgeluk, Glenn, Weening, Karin, Verstichel, Greet, Bonte, Sarah, Taghon, Tom, Leclercq, Georges, Kerre, Tessa, Debets, Reno, Vermijlen, David, Abken, Hinrich, Vandekerckhove, Bart
Publicado 2017