Alterations of kynurenine pathway in alcohol use disorder and abstinence: a link with gut microbiota, peripheral inflammation and psychological symptoms

por Leclercq, Sophie, Schwarz, Markus, Delzenne, Nathalie M., Stärkel, Peter, de Timary, Philippe
Publicado 2021

Increased Age, but Not Parity Predisposes to Higher Bacteriuria Burdens Due to Streptococcus Urinary Tract Infection and Influences Bladder Cytokine Responses, Which Develop Indepe...

por Sullivan, Matthew J., Carey, Alison J., Leclercq, Sophie Y., Tan, Chee K., Ulett, Glen C.
Publicado 2016

Pathogenesis of Streptococcus urinary tract infection depends on bacterial strain and β-hemolysin/cytolysin that mediates cytotoxicity, cytokine synthesis, inflammation and virulen...

por Leclercq, Sophie Y., Sullivan, Matthew J., Ipe, Deepak S., Smith, Joshua P., Cripps, Allan W., Ulett, Glen C.
Publicado 2016

Liver alterations are not improved by inulin supplementation in alcohol use disorder patients during alcohol withdrawal: A pilot randomized, double-blind, placebo-controlled study

por Amadieu, Camille, Maccioni, Luca, Leclercq, Sophie, Neyrinck, Audrey M., Delzenne, Nathalie M., de Timary, Philippe, Stärkel, Peter
Publicado 2022

Toll-like receptor 2 activation in monocytes contributes to systemic inflammation and alcohol-associated liver disease in humans

por Maccioni, Luca, Kasavuli, Joyce, Leclercq, Sophie, Pirlot, Boris, Laloux, Géraldine, Horsmans, Yves, Leclercq, Isabelle, Schnabl, Bernd, Stärkel, Peter
Publicado 2023

Interplay between Penicillin-binding proteins and SEDS proteins promotes bacterial cell wall synthesis

por Leclercq, Sophie, Derouaux, Adeline, Olatunji, Samir, Fraipont, Claudine, Egan, Alexander J. F., Vollmer, Waldemar, Breukink, Eefjan, Terrak, Mohammed
Publicado 2017

How Probiotics Affect the Microbiota

por Wieërs, Grégoire, Belkhir, Leila, Enaud, Raphaël, Leclercq, Sophie, Philippart de Foy, Jean-Michel, Dequenne, Isabelle, de Timary, Philippe, Cani, Patrice D.
Publicado 2020

Intestinal permeability, microbial translocation, changes in duodenal and fecal microbiota, and their associations with alcoholic liver disease progression in humans

por Maccioni, Luca, Gao, Bei, Leclercq, Sophie, Pirlot, Boris, Horsmans, Yves, De Timary, Philippe, Leclercq, Isabelle, Fouts, Derrick, Schnabl, Bernd, Stärkel, Peter
Publicado 2020

Low-dose penicillin in early life induces long-term changes in murine gut microbiota, brain cytokines and behavior

por Leclercq, Sophie, Mian, Firoz M., Stanisz, Andrew M., Bindels, Laure B., Cambier, Emmanuel, Ben-Amram, Hila, Koren, Omry, Forsythe, Paul, Bienenstock, John
Publicado 2017

Deficient IL‐6/Stat3 Signaling, High TLR7, and Type I Interferons in Early Human Alcoholic Liver Disease: A Triad for Liver Damage and Fibrosis

por Stärkel, Peter, Schnabl, Bernd, Leclercq, Sophie, Komuta, Mina, Bataller, Ramon, Argemi, Josepmaria, Palma, Elena, Chokshi, Shilpa, Hellerbrand, Claus, Maccioni, Luca, Lanthier, Nicolas, Leclercq, Isabelle
Publicado 2019

The Loss of Metabolic Control on Alcohol Drinking in Heavy Drinking Alcohol-Dependent Subjects

por de Timary, Philippe, Cani, Patrice D., Duchemin, Julie, Neyrinck, Audrey M., Gihousse, Dominique, Laterre, Pierre-François, Badaoui, Abdenor, Leclercq, Sophie, Delzenne, Nathalie M., Stärkel, Peter
Publicado 2012

Recombinant Invasive Lactococcus lactis Carrying a DNA Vaccine Coding the Ag85A Antigen Increases INF-γ, IL-6, and TNF-α Cytokines after Intranasal Immunization

por Mancha-Agresti, Pamela, de Castro, Camila Prosperi, dos Santos, Janete S. C., Araujo, Maíra A., Pereira, Vanessa B., LeBlanc, Jean G., Leclercq, Sophie Y., Azevedo, Vasco
Publicado 2017

Hepatoprotective Effects of Indole, a Gut Microbial Metabolite, in Leptin-Deficient Obese Mice

por Knudsen, Christelle, Neyrinck, Audrey M, Leyrolle, Quentin, Baldin, Pamela, Leclercq, Sophie, Rodriguez, Julie, Beaumont, Martin, Cani, Patrice D, Bindels, Laure B, Lanthier, Nicolas, Delzenne, Nathalie M
Publicado 2021

Role of inflammation in alcohol-related brain abnormalities: a translational study

por Lanquetin, Anastasia, Leclercq, Sophie, de Timary, Philippe, Segobin, Shailendra, Naveau, Mikaël, Coulbault, Laurent, Maccioni, Paola, Lorrai, Irene, Colombo, Giancarlo, Vivien, Denis, Rubio, Marina, Pitel, Anne-Lise
Publicado 2021

Restoring an adequate dietary fiber intake by inulin supplementation: a pilot study showing an impact on gut microbiota and sociability in alcohol use disorder patients

por Amadieu, Camille, Coste, Valentin, Neyrinck, Audrey M., Thijssen, Victoria, Leyrolle, Quentin, Bindels, Laure B., Piessevaux, Hubert, Stärkel, Peter, de Timary, Philippe, Delzenne, Nathalie M., Leclercq, Sophie
Publicado 2021

A New Broad Range Plasmid for DNA Delivery in Eukaryotic Cells Using Lactic Acid Bacteria: In Vitro and In Vivo Assays

por Mancha-Agresti, Pamela, Drumond, Mariana Martins, Carmo, Fillipe Luiz Rosa do, Santos, Monica Morais, Santos, Janete Soares Coelho dos, Venanzi, Franco, Chatel, Jean-Marc, Leclercq, Sophie Yvette, Azevedo, Vasco
Publicado 2016

Microencapsulation of Lactic Acid Bacteria Improves the Gastrointestinal Delivery and in situ Expression of Recombinant Fluorescent Protein

por Coelho-Rocha, Nina D., de Castro, Camila P., de Jesus, Luis C. L., Leclercq, Sophie Y., de Cicco Sandes, Savio H., Nunes, Alvaro C., Azevedo, Vasco, Drumond, Mariana M., Mancha-Agresti, Pamela
Publicado 2018

Antigenic Peptides Capable of Inducing Specific Antibodies for Detection of the Major Alterations Found in Type 2B Von Willebrand Disease

por Paro, Marina de Oliveira, Ferreira, Cyntia Silva, Vieira, Fernanda Silva, de Santana, Marcos Aurélio, Castro-Borges, William, Namen-Lopes, Maria Sueli Silva, Leclercq, Sophie Yvette, Velloso-Rodrigues, Cibele, Guerra de Andrade, Milton Hércules
Publicado 2013

Lactococcus lactis carrying the pValac DNA expression vector coding for IL-10 reduces inflammation in a murine model of experimental colitis

por Zurita-Turk, Meritxell, del Carmen, Silvina, Santos, Ana CG, Pereira, Vanessa B, Cara, Denise C, Leclercq, Sophie Y, de LeBlanc, Alejandra dM, Azevedo, Vasco, Chatel, Jean-Marc, LeBlanc, Jean G, Miyoshi, Anderson
Publicado 2014

Lactococcus lactis FNBPA(+) (pValac:e6ag85a) Induces Cellular and Humoral Immune Responses After Oral Immunization of Mice

por de Castro, Camila Prósperi, Souza, Bianca Mendes, Mancha-Agresti, Pamela, Pereira, Vanessa Bastos, Zurita-Turk, Meritxell, Preisser, Tatiane Melo, da Cunha, Vanessa Pecini, dos Santos, Janete Soares Coelho, Leclercq, Sophie Yvette, Azevedo, Vasco, Miyoshi, Anderson
Publicado 2021