Predicting Time to Death After Withdrawal of Life-Sustaining Treatment in Children

por Winter, Meredith C., Ledbetter, David R.
Publicado 2022

Predicting High Flow Nasal Cannula Failure in an Intensive Care Unit Using a Recurrent Neural Network With Transfer Learning and Input Data Perseveration: Retrospective Analysis

por Pappy, George, Aczon, Melissa, Wetzel, Randall, Ledbetter, David
Publicado 2022

Genomic Variation: Lessons Learned from Whole-Genome CNV Analysis

por Riggs, Erin Rooney, Ledbetter, David H., Martin, Christa Lese
Publicado 2014

Shift happens: family background influences clinical variability in genetic neurodevelopmental disorders

por Finucane, Brenda, Challman, Thomas D., Martin, Christa Lese, Ledbetter, David H.
Publicado 2016

Continuous Prediction of Mortality in the PICU: A Recurrent Neural Network Model in a Single-Center Dataset*

por Aczon, Melissa D., Ledbetter, David R., Laksana, Eugene, Ho, Long V., Wetzel, Randall C.
Publicado 2021

American College of Medical Genetics Statement on Diagnostic Testing for Uniparental Disomy

por Shaffer, Lisa G., Agan, Noelle, Goldberg, James D., Ledbetter, David H., Longshore, John W., Cassidy, Suzanne B.
Publicado 2001

Development of a deep learning model that predicts Bi-level positive airway pressure failure

por Im, Daniel D., Laksana, Eugene, Ledbetter, David R., Aczon, Melissa D., Khemani, Robinder G., Wetzel, Randall C.
Publicado 2022

Human Preferences for Symmetry: Subjective Experience, Cognitive Conflict and Cortical Brain Activity

por Evans, David W., Orr, Patrick T., Lazar, Steven M., Breton, Daniel, Gerard, Jennifer, Ledbetter, David H., Janosco, Kathleen, Dotts, Jessica, Batchelder, Holly
Publicado 2012

Population Genomic Screening for Genetic Etiologies of Neurodevelopmental/Psychiatric Disorders Demonstrates Personal Utility and Positive Participant Responses

por Wain, Karen E., Tolwinski, Kasia, Palen, Emily, Heidlebaugh, Alexis R., Holdren, Karahlyn, Walsh, Lauren Kasparson, Oetjens, Matthew T., Ledbetter, David H., Martin, Christa Lese
Publicado 2021

The Geisinger MyCode Community Health Initiative: an electronic health record-linked biobank for Precision Medicine research

por Carey, David J., Fetterolf, Samantha N., Davis, F. Daniel, Faucett, William A., Kirchner, H. Lester, Mirshahi, Uyenlinh, Murray, Michael F., Smelser, Diane T., Gerhard, Glenn S., Ledbetter, David H.
Publicado 2016

Electronic health record analysis identifies kidney disease as the leading risk factor for hospitalization in confirmed COVID-19 patients

por Oetjens, Matthew T., Luo, Jonathan Z., Chang, Alexander, Leader, Joseph B., Hartzel, Dustin N., Moore, Bryn S., Strande, Natasha T., Kirchner, H. Lester, Ledbetter, David H., Justice, Anne E., Carey, David J., Mirshahi, Tooraj
Publicado 2020

Identification of Neuropsychiatric Copy Number Variants in a Health Care System Population

por Martin, Christa Lese, Wain, Karen E., Oetjens, Matthew T., Tolwinski, Kasia, Palen, Emily, Hare-Harris, Abby, Habegger, Lukas, Maxwell, Evan K., Reid, Jeffrey G., Walsh, Lauren Kasparson, Myers, Scott M., Ledbetter, David H.
Publicado 2020

Insufficient Evidence for “Autism-Specific” Genes

por Myers, Scott M., Challman, Thomas D., Bernier, Raphael, Bourgeron, Thomas, Chung, Wendy K., Constantino, John N., Eichler, Evan E., Jacquemont, Sebastien, Miller, David T., Mitchell, Kevin J., Zoghbi, Huda Y., Martin, Christa Lese, Ledbetter, David H.
Publicado 2020

Meta-analysis and multidisciplinary consensus statement: exome sequencing is a first-tier clinical diagnostic test for individuals with neurodevelopmental disorders

por Srivastava, Siddharth, Love-Nichols, Jamie A., Dies, Kira A., Ledbetter, David H., Martin, Christa L., Chung, Wendy K., Firth, Helen V., Frazier, Thomas, Hansen, Robin L., Prock, Lisa, Brunner, Han, Hoang, Ny, Scherer, Stephen W., Sahin, Mustafa, Miller, David T.
Publicado 2019

Correction: Meta-analysis and multidisciplinary consensus statement: exome sequencing is a first-tier clinical diagnostic test for individuals with neurodevelopmental disorders

por Srivastava, Siddharth, Love-Nichols, Jamie A., Dies, Kira A., Ledbetter, David H., Martin, Christa L., Chung, Wendy K., Firth, Helen V., Frazier, Thomas, Hansen, Robin L., Prock, Lisa, Brunner, Han, Hoang, Ny, Scherer, Stephen W., Sahin, Mustafa, Miller, David T.
Publicado 2020

The struggle to find reliable results in exome sequencing data: filtering out Mendelian errors

por Patel, Zubin H., Kottyan, Leah C., Lazaro, Sara, Williams, Marc S., Ledbetter, David H., Tromp, hbGerard, Rupert, Andrew, Kohram, Mojtaba, Wagner, Michael, Husami, Ammar, Qian, Yaping, Valencia, C. Alexander, Zhang, Kejian, Hostetter, Margaret K., Harley, John B., Kaufman, Kenneth M.
Publicado 2014

Analysis of 17 genes detects mutations in 81% of 811 patients with lissencephaly

por Di Donato, Nataliya, Timms, Andrew E., Aldinger, Kimberly A., Mirzaa, Ghayda M., Bennett, James T., Collins, Sarah, Olds, Carissa, Mei, Davide, Chiari, Sara, Carvill, Gemma, Myers, Candace T., Rivière, Jean-Baptiste, Zaki, Maha S., Gleeson, Joseph G., Rump, Andreas, Conti, Valerio, Parrini, Elena, Ross, M. Elizabeth, Ledbetter, David H., Guerrini, Renzo, Dobyns, William B.
Publicado 2018

Clinical outcomes of a genomic screening program for actionable genetic conditions

por Buchanan, Adam H., Lester Kirchner, H., Schwartz, Marci L. B., Kelly, Melissa A., Schmidlen, Tara, Jones, Laney K., Hallquist, Miranda L. G., Rocha, Heather, Betts, Megan, Schwiter, Rachel, Butry, Loren, Lazzeri, Amanda L., Frisbie, Lauren R., Rahm, Alanna Kulchak, Hao, Jing, Willard, Huntington F., Martin, Christa L., Ledbetter, David H., Williams, Marc S., Sturm, Amy C.
Publicado 2020

Common genetic variants, acting additively, are a major source of risk for autism

por Klei, Lambertus, Sanders, Stephan J, Murtha, Michael T, Hus, Vanessa, Lowe, Jennifer K, Willsey, A Jeremy, Moreno-De-Luca, Daniel, Yu, Timothy W, Fombonne, Eric, Geschwind, Daniel, Grice, Dorothy E, Ledbetter, David H, Lord, Catherine, Mane, Shrikant M, Martin, Christa Lese, Martin, Donna M, Morrow, Eric M, Walsh, Christopher A, Melhem, Nadine M, Chaste, Pauline, Sutcliffe, James S, State, Matthew W, Cook, Edwin H, Roeder, Kathryn, Devlin, Bernie
Publicado 2012

Implementing genomic medicine in the clinic: the future is here

por Manolio, Teri A., Chisholm, Rex L., Ozenberger, Brad, Roden, Dan M., Williams, Marc S., Wilson, Richard, Bick, David, Bottinger, Erwin P., Brilliant, Murray H., Eng, Charis, Frazer, Kelly A., Korf, Bruce, Ledbetter, David H., Lupski, James R., Marsh, Clay, Mrazek, David, Murray, Michael F., O'Donnell, Peter H., Rader, Daniel J., Relling, Mary V., Shuldiner, Alan R., Valle, David, Weinshilboum, Richard, Green, Eric D., Ginsburg, Geoffrey S.
Publicado 2013