Identification of novel myeloma-specific XBP1 peptides able to generate cytotoxic T lymphocytes: A potential therapeutic application in multiple myeloma

por Bae, Jooeun, Carrasco, Ruben, Lee, Ann-Hwee, Tai, Yu-Tzu, Anderson, Kenneth C., Munshi, Nikhil C.
Publicado 2011

Transcriptional profiling of PPARα−/− and CREB3L3−/− livers reveals disparate regulation of hepatoproliferative and metabolic functions of PPARα

por Ruppert, Philip M. M., Park, Jong-Gil, Xu, Xu, Hur, Kyu Yeon, Lee, Ann-Hwee, Kersten, Sander
Publicado 2019

CREBH-FGF21 axis improves hepatic steatosis by suppressing adipose tissue lipolysis

por Park, Jong-Gil, Xu, Xu, Cho, Sungyun, Hur, Kyu Yeon, Lee, Myung-Shik, Kersten, Sander, Lee, Ann-Hwee
Publicado 2016

Lenalidomide Polarizes Th1-specific Anti-tumor Immune Response and Expands XBP1 Antigen-Specific Central Memory CD3(+)CD8(+) T cells against Various Solid Tumors

por Bae, Jooeun, Keskin, Derin B, Cowens, Kristen, Lee, Ann-Hwee, Dranoff, Glen, Munshi, Nikhil C, Anderson, Kenneth C
Publicado 2015

The transcription factor XBP1 is selectively required for eosinophil differentiation

por Bettigole, Sarah E., Lis, Raphael, Adoro, Stanley, Lee, Ann-Hwee, Spencer, Lisa A., Weller, Peter F., Glimcher, Laurie H.
Publicado 2015

A negative feedback loop between XBP1 and Fbw7 regulates cancer development

por Chae, Unbin, Lee, Heejin, Kim, Bokyung, Jung, Haiyoung, Kim, Byeong Mo, Lee, Ann- Hwee, Lee, Dong-Seok, Min, Sang-Hyun
Publicado 2019

Inducible hepatic expression of CREBH mitigates diet-induced obesity, insulin resistance, and hepatic steatosis in mice

por Krumm, Christopher S., Xu, Xu, Bare, Curtis J., Holman, Corey D., Kersten, Sander, Dow, Lukas E., Lee, Ann-Hwee, Cohen, David E.
Publicado 2021

IRE1α activation protects mice against acetaminophen-induced hepatotoxicity

por Hur, Kyu Yeon, So, Jae-Seon, Ruda, Vera, Frank-Kamenetsky, Maria, Fitzgerald, Kevin, Koteliansky, Victor, Iwawaki, Takao, Glimcher, Laurie H., Lee, Ann-Hwee
Publicado 2012

XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development

por Todd, Derrick J., McHeyzer-Williams, Louise J., Kowal, Czeslawa, Lee, Ann-Hwee, Volpe, Bruce T., Diamond, Betty, McHeyzer-Williams, Michael G., Glimcher, Laurie H.
Publicado 2009

Dissociation of Inositol-requiring Enzyme (IRE1α)-mediated c-Jun N-terminal Kinase Activation from Hepatic Insulin Resistance in Conditional X-box-binding Protein-1 (XBP1) Knock-ou...

por Jurczak, Michael J., Lee, Ann-Hwee, Jornayvaz, Francois R., Lee, Hui-Young, Birkenfeld, Andreas L., Guigni, Blas A., Kahn, Mario, Samuel, Varman T., Glimcher, Laurie H., Shulman, Gerald I.
Publicado 2012

XBP1-KLF9 Axis Acts as a Molecular Rheostat to Control the Transition from Adaptive to Cytotoxic Unfolded Protein Response

por Fink, Emily E., Moparthy, Sudha, Bagati, Archis, Bianchi-Smiraglia, Anna, Lipchick, Brittany C., Wolff, David W., Roll, Matthew V., Wang, Jianmin, Liu, Song, Bakin, Andrei V., Kandel, Eugene S., Lee, Ann-Hwee, Nikiforov, Mikhail A.
Publicado 2018

The Differential Expression of Cide Family Members is Associated with Nafld Progression from Steatosis to Steatohepatitis

por Sans, Arnaud, Bonnafous, Stéphanie, Rousseau, Déborah, Patouraux, Stéphanie, Canivet, Clémence M., Leclere, Pierre S., Tran-Van-Nhieu, Jeanne, Luci, Carmelo, Bailly-Maitre, Béatrice, Xu, Xu, Lee, Ann-Hwee, Minehira, Kaori, Anty, Rodolphe, Tran, Albert, Iannelli, Antonio, Gual, Philippe
Publicado 2019

IRE1α is an endogenous substrate of endoplasmic reticulum-associated degradation

por Sun, Shengyi, Shi, Guojun, Sha, Haibo, Ji, Yewei, Han, Xuemei, Shu, Xin, Ma, Hongming, Inoue, Takamasa, Gao, Beixue, Kim, Hana, Bu, Pengcheng, Guber, Robert D., Shen, Xiling, Lee, Ann-Hwee, Iwawaki, Takao, Paton, Adrienne W., Paton, James C., Fang, Deyu, Tsai, Billy, Yates, John R., Wu, Haoquan, Kersten, Sander, Long, Qiaoming, Duhamel, Gerald E., Simpson, Kenneth W., Qi, Ling
Publicado 2015