A novel ligand-receptor relationship between families of ribonucleases and receptor tyrosine kinases

por Wang, Ying-Nai, Lee, Heng-Huan, Hung, Mien-Chie
Publicado 2018

The impact of PD-L1 N-linked glycosylation on cancer therapy and clinical diagnosis

por Wang, Ying-Nai, Lee, Heng-Huan, Hsu, Jennifer L., Yu, Dihua, Hung, Mien-Chie
Publicado 2020

Switching Hedgehog inhibitors and other strategies to address resistance when treating advanced basal cell carcinoma

por Doan, Hung Q., Chen, Leon, Nawas, Zeena, Lee, Heng-Huan, Silapunt, Sirunya, Migden, Michael
Publicado 2021

Ribonuclease 1 Enhances Antitumor Immunity against Breast Cancer by Boosting T cell Activation

por Wang, Ying-Nai, Lee, Heng-Huan, Jiang, Zhou, Chan, Li-Chuan, Hortobagyi, Gabriel N., Yu, Dihua, Hung, Mien-Chie
Publicado 2023

An optimized protocol for PD-L1 pathological assessment with patient sample deglycosylation to improve correlation with therapeutic response

por Wang, Ying-Nai, Lee, Heng-Huan, Wei, Yongkun, Chu, Yu-Yi, Xia, Weiya, Wang, Michael, Yu, Dihua, Hung, Mien-Chie
Publicado 2022

Inhibition of Type I Insulin-Like Growth Factor Receptor Signaling Attenuates the Development of Breast Cancer Brain Metastasis

por Saldana, Sandra M., Lee, Heng-Huan, Lowery, Frank J., Khotskaya, Yekaterina B., Xia, Weiya, Zhang, Chenyu, Chang, Shih-Shin, Chou, Chao-Kai, Steeg, Patricia S., Yu, Dihua, Hung, Mien-Chie
Publicado 2013

Pirtobrutinib and venetoclax combination overcomes resistance to targeted and chimeric antigen receptor T-cell therapy in aggressive mantle cell lymphoma

por Liu, Yang, Yan, Fangfang, Jiang, Vivian Changying, Li, Yijing, Che, Yuxuan, McIntosh, Joseph, Jordan, Alexa, Hou, Ian, Nie, Lei, Jin, Jingling, Wang, Wei, Lee, Heng-Huan, Yao, Yixin, Wang, Michael
Publicado 2022

Dual targeting of CDK4/6 and Bcl-2 exhibits a potent antitumor effect on mantle cell lymphoma

por Che, Yuxuan, Liu, Yang, Li, Yijing, McIntosh, Joseph M., Jordan, Alexa, Yan, Fangfang, Wang, Wei, Nie, Lei, Lee, Heng-Huan, Jin, Jingling, Yao, Yixin, Zhao, Zhongming, Jiang, Vivian Changying, Wang, Michael
Publicado 2023

PD-1 blockade in combination with dasatinib potentiates induction of anti-acute lymphocytic leukemia immunity

por Koller, Paul, Baran, Natalia, Harutyunyan, Karine, Cavazos, Antonio, Mallampati, Saradhi, Chin, Renee L, Jiang, Zhou, Sun, Xian, Lee, Heng-Huan, Hsu, Jennifer L, Williams, Patrick, Huang, Xuelin, Curran, Michael A, Hung, Mien-Chie, Konopleva, Marina
Publicado 2023

Potentiation of apoptosis in drug-resistant mantle cell lymphoma cells by MCL-1 inhibitor involves downregulation of inhibitor of apoptosis proteins

por Li, Yijing, Lee, Heng-Huan, Jiang, Vivian Changying, Che, Yuxuan, McIntosh, Joseph, Jordan, Alexa, Vargas, Jovanny, Zhang, Tianci, Yan, Fangfang, Simmons, Margaret Elizabeth, Wang, Wei, Nie, Lei, Yao, Yixin, Jain, Preetesh, Wang, Michael, Liu, Yang
Publicado 2023

p53 regulates epithelial-mesenchymal transition (EMT) and stem cell properties through modulating miRNAs

por Chang, Chun-Ju, Chao, Chi-Hong, Xia, Weiya, Yang, Jer-Yen, Xiong, Yan, Li, Chia-Wei, Yu, Wen-Hsuan, Rehman, Sumaiyah K., Hsu, Jennifer L., Lee, Heng-Huan, Liu, Mo, Chen, Chun-Te, Yu, Dihua, Hung, Mien-Chie
Publicado 2011

TIGIT is the central player in T-cell suppression associated with CAR T-cell relapse in mantle cell lymphoma

por Jiang, Vivian Changying, Hao, Dapeng, Jain, Preetesh, Li, Yijing, Cai, Qingsong, Yao, Yixin, Nie, Lei, Liu, Yang, Jin, Jingling, Wang, Wei, Lee, Heng-Huan, Che, Yuxuan, Dai, Enyu, Han, Guangchun, Wang, Ruiping, Rai, Kunal, Futreal, Andrew, Flowers, Christopher, Wang, Linghua, Wang, Michael
Publicado 2022

Small-molecule MMP2/MMP9 inhibitor SB-3CT modulates tumor immune surveillance by regulating PD-L1

por Ye, Youqiong, Kuang, Xinwei, Xie, Zuozhong, Liang, Long, Zhang, Zhao, Zhang, Yongchang, Ma, Fangyu, Gao, Qian, Chang, Ruimin, Lee, Heng-Huan, Zhao, Shuang, Su, Juan, Li, Hui, Peng, Jingbo, Chen, Huifang, Yin, Minzhu, Peng, Cong, Yang, Nong, Wang, Jing, Liu, Jing, Liu, Hong, Han, Leng, Chen, Xiang
Publicado 2020

Cotargeting of BTK and MALT1 overcomes resistance to BTK inhibitors in mantle cell lymphoma

por Jiang, Vivian Changying, Liu, Yang, Lian, Junwei, Huang, Shengjian, Jordan, Alexa, Cai, Qingsong, Lin, Ruitao, Yan, Fangfang, McIntosh, Joseph, Li, Yijing, Che, Yuxuan, Chen, Zhihong, Vargas, Jovanny, Badillo, Maria, Bigcal, John Nelson, Lee, Heng-Huan, Wang, Wei, Yao, Yixin, Nie, Lei, Flowers, Christopher R., Wang, Michael
Publicado 2023

GSK3β inactivation promotes the oncogenic functions of EZH2 and enhances methylation of H3K27 in human breast cancers

por Ko, How-Wen, Lee, Heng-Huan, Huo, Longfei, Xia, Weiya, Yang, Cheng-Chieh, Hsu, Jennifer L., Li, Long-Yuan, Lai, Chien-Chen, Chan, Li-Chuan, Cheng, Chien-Chia, Labaff, Adam M., Liao, Hsin-Wei, Lim, Seung-Oe, Li, Chia-Wei, Wei, Yongkun, Nie, Lei, Yamaguchi, Hirohito, Hung, Mien-Chie
Publicado 2016

Ephrin receptor A10 monoclonal antibodies and the derived chimeric antigen receptor T cells exert an antitumor response in mouse models of triple-negative breast cancer

por Cha, Jong-Ho, Chan, Li-Chuan, Wang, Ying-Nai, Chu, Yu-Yi, Wang, Chie-Hong, Lee, Heng-Huan, Xia, Weiya, Shyu, Woei-Cherng, Liu, Shih-Ping, Yao, Jun, Chang, Chiung-Wen, Cheng, Fan-Ru, Liu, Jielin, Lim, Seung-Oe, Hsu, Jennifer L., Yang, Wen-Hao, Hortobagyi, Gabriel N., Lin, Chunru, Yang, Liuqing, Yu, Dihua, Jeng, Long-Bin, Hung, Mien-Chie
Publicado 2022

Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity

por Li, Chia-Wei, Lim, Seung-Oe, Xia, Weiya, Lee, Heng-Huan, Chan, Li-Chuan, Kuo, Chu-Wei, Khoo, Kay-Hooi, Chang, Shih-Shin, Cha, Jong-Ho, Kim, Taewan, Hsu, Jennifer L., Wu, Yun, Hsu, Jung-Mao, Yamaguchi, Hirohito, Ding, Qingqing, Wang, Yan, Yao, Jun, Lee, Cheng-Chung, Wu, Hsing-Ju, Sahin, Aysegul A., Allison, James P., Yu, Dihua, Hortobagyi, Gabriel N., Hung, Mien-Chie
Publicado 2016

Targeting the ALK–CDK9-Tyr19 kinase cascade sensitizes ovarian and breast tumors to PARP inhibition via destabilization of the P-TEFb complex

por Chu, Yu-Yi, Chen, Mei-Kuang, Wei, Yongkun, Lee, Heng-Huan, Xia, Weiya, Wang, Ying-Nai, Yam, Clinton, Hsu, Jennifer L., Wang, Hung-Ling, Chang, Wei-Chao, Yamaguchi, Hirohito, Jiang, Zhou, Liu, Chunxiao, Li, Ching-Fei, Nie, Lei, Chan, Li-Chuan, Gao, Yuan, Wang, Shao-Chun, Liu, Jinsong, Westin, Shannon N., Lee, Sanghoon, Sood, Anil K., Yang, Liuqing, Hortobagyi, Gabriel N., Yu, Dihua, Hung, Mien-Chie
Publicado 2022

Human ribonuclease 1 serves as a secretory ligand of ephrin A4 receptor and induces breast tumor initiation

por Lee, Heng-Huan, Wang, Ying-Nai, Yang, Wen-Hao, Xia, Weiya, Wei, Yongkun, Chan, Li-Chuan, Wang, Yu-Han, Jiang, Zhou, Xu, Shouping, Yao, Jun, Qiu, Yufan, Hsu, Yi-Hsin, Hwang, Wei-Lun, Yan, Meisi, Cha, Jong-Ho, Hsu, Jennifer L., Shen, Jia, Ye, Yuanqing, Wu, Xifeng, Hou, Ming-Feng, Tseng, Lin-Ming, Wang, Shao-Chun, Pan, Mei-Ren, Yang, Chin-Hua, Wang, Yuan-Liang, Yamaguchi, Hirohito, Pang, Da, Hortobagyi, Gabriel N., Yu, Dihua, Hung, Mien-Chie
Publicado 2021