Ring size changes in the development of class I HDAC inhibitors

por Cho, Er-Chieh, Liu, Chi-Yuan, Tang, Di-Wei, Lee, Hsueh-Yun
Publicado 2021

Structure-guided design of anti-cancer ribonucleotide reductase inhibitors

por Misko, Tessianna A., Liu, Yi-Ting, Harris, Michael E., Oleinick, Nancy L., Pink, John, Lee, Hsueh-Yun, Dealwis, Chris G.
Publicado 2019

Effect of 3-subsitution of quinolinehydroxamic acids on selectivity of histone deacetylase isoforms

por Mehndiratta, Samir, Chen, Mei-Chuan, Chao, Yuh-Hsuan, Lee, Cheng-Hsin, Liou, Jing-Ping, Lai, Mei-Jung, Lee, Hsueh-Yun
Publicado 2020

Synthesis and Biological Evaluation of 4-Aroyl-6,7,8-Trimethoxyquinolines as a Novel Class of Anticancer Agents

por Hsieh, Cheng-Chih, Lee, Hsueh-Yun, Nien, Chih-Ying, Kuo, Ching-Chuan, Chang, Chi-Yen, Chang, Jang-Yang, Liou, Jing-Ping
Publicado 2011

Synthesis and evaluation of potent (iso)ellipticine-based inhibitors of MYLK4 accessed via expeditious synthesis from isoquinolin-5-ol

por Lee, Szu, Chao, Min-Wu, Wu, Yi-Wen, Hsu, Chia-Min, Lin, Tony Eight, Hsu, Kai-Cheng, Pan, Shiow-Lin, Lee, Hsueh-Yun
Publicado 2023

CuI-mediated synthesis of 1-aryl-5,6,7-trimethoxybenzimidazoles as potent antitubulin agents

por Peng, Cong-Min, Wang, Shih-Wei, Hwang, Yi-Lin, Sun, Wen-Chun, Chiu, Li-Pin, Liu, Yi-Ting, Lai, Yu-Wei, Lee, Hsueh-Yun
Publicado 2023

Correction: CuI-mediated synthesis of 1-aryl-5,6,7-trimethoxybenzimidazoles as potent antitubulin agents

por Peng, Cong-Min, Wang, Shih-Wei, Hwang, Yi-Lin, Sun, Wen-Chun, Chiu, Li-Pin, Liu, Yi-Ting, Lai, Yu-Wei, Lee, Hsueh-Yun
Publicado 2023

Anticancer Activity of MPT0E028, a Novel Potent Histone Deacetylase Inhibitor, in Human Colorectal Cancer HCT116 Cells In Vitro and In Vivo

por Huang, Han-Lin, Lee, Hsueh-Yun, Tsai, An-Chi, Peng, Chieh-Yu, Lai, Mei-Jung, Wang, Jing-Chi, Pan, Shiow-Lin, Teng, Che-Ming, Liou, Jing-Ping
Publicado 2012

Correction: Anticancer Activity of MPT0E028, a Novel Potent Histone Deacetylase Inhibitor, in Human Colorectal Cancer HCT116 Cells In Vitro and In Vivo

por Huang, Han-Li, Lee, Hsueh-Yun, Tsai, An-Chi, Peng, Chieh-Yu, Lai, Mei-Jung, Wang, Jing-Chi, Pan, Shiow-Lin, Teng, Che-Ming, Liou, Jing-Ping
Publicado 2012

A novel action mechanism for MPT0G013, a derivative of arylsulfonamide, inhibits tumor angiogenesis through up-regulation of TIMP3 expression

por Wang, Chih-Ya, Liou, Jing-Ping, Tsai, An-Chi, Lai, Mei-Jung, Liu, Yi-Min, Lee, Hsueh-Yun, Wang, Jing-Chi, Pan, Shiow-Lin, Teng, Che-Ming
Publicado 2014

HDAC inhibitor protects chronic cerebral hypoperfusion and oxygen‐glucose deprivation injuries via H3K14 and H4K5 acetylation‐mediated BDNF expression

por Fang, Yao‐Ching, Chan, Lung, Liou, Jing‐Ping, Tu, Yong‐Kwang, Lai, Mei‐Jung, Chen, Chin‐I, Vidyanti, Amelia Nur, Lee, Hsueh‐Yun, Hu, Chaur‐Jong
Publicado 2020

Novel oral histone deacetylase inhibitor, MPT0E028, displays potent growth-inhibitory activity against human B-cell lymphoma in vitro and in vivo

por Huang, Han-Li, Peng, Chieh-Yu, Lai, Mei-Jung, Chen, Chun-Han, Lee, Hsueh-Yun, Wang, Jing-Chi, Liou, Jing-Ping, Pan, Shiow-Lin, Teng, Che-Ming
Publicado 2014

Structure-based virtual screening and biological evaluation of novel small-molecule BTK inhibitors

por Lin, Tony Eight, Sung, Li-Chin, Chao, Min-Wu, Li, Min, Zheng, Jia-Huei, Sung, Tzu-Ying, Hsieh, Jui-Hua, Yang, Chia-Ron, Lee, Hsueh-Yun, Cho, Er-Chieh, Hsu, Kai-Cheng
Publicado 2021

A Novel Dual HDAC6 and Tubulin Inhibitor, MPT0B451, Displays Anti-tumor Ability in Human Cancer Cells in Vitro and in Vivo

por Wu, Yi-Wen, Hsu, Kai-Cheng, Lee, Hsueh-Yun, Huang, Tsui-Chin, Lin, Tony E., Chen, Yi-Ling, Sung, Ting-Yi, Liou, Jing-Ping, Hwang-Verslues, Wendy W., Pan, Shiow-Lin, HuangFu, Wei-Chun
Publicado 2018

In silico identification and biological evaluation of a selective MAP4K4 inhibitor against pancreatic cancer

por Chang, Chao-Di, Chao, Min-Wu, Lee, Hsueh-Yun, Liu, Yi-Ting, Tu, Huang-Ju, Lien, Ssu-Ting, Lin, Tony Eight, Sung, Tzu-Ying, Yen, Shih-Chung, Huang, Sing-Han, Hsu, Kai-Cheng, Pan, Shiow-Lin
Publicado 2023

An oral quinoline derivative, MPT0B392, causes leukemic cells mitotic arrest and overcomes drug resistant cancer cells

por Chao, Min-Wu, Huang, Han-Li, HuangFu, Wei-Chun, Hsu, Kai-Cheng, Liu, Yi-Min, Wu, Yi-Wen, Lin, Chao-Feng, Chen, Yi-Lin, Lai, Mei-Jung, Lee, Hsueh-Yun, Liou, Jing-Ping, Teng, Che-Ming, Yang, Chia-Ron
Publicado 2017