6′-β-Fluoro-Homoaristeromycin and 6′-Fluoro-Homoneplanocin A Are Potent Inhibitors of Chikungunya Virus Replication through Their Direct Effect on Viral Nonstructural Protein 1...

por Kovacikova, Kristina, Morren, Bas M., Tas, Ali, Albulescu, Irina C., van Rijswijk, Robin, Jarhad, Dnyandev B., Shin, Young Sup, Jang, Min Hwan, Kim, Gyudong, Lee, Hyuk Woo, Jeong, Lak Shin, Snijder, Eric J., van Hemert, Martijn J.
Publicado 2020

In Silico Discovery of 5′-Modified 7-Deoxy-7-ethynyl-4′-thioadenosine as a HASPIN Inhibitor and Its Synergistic Anticancer Effect with the PLK1 Inhibitor

por Kwon, Eun-Ji, Mashelkar, Karishma K., Seo, Juhee, Shin, Yoon-Ze, Sung, Kisu, Jang, Sung Chul, Cheon, Sang Won, Lee, Haeseung, Lee, Hyuk Woo, Kim, Gyudong, Han, Byung Woo, Lee, Sang Kook, Jeong, Lak Shin, Cha, Hyuk-Jin
Publicado 2023

Discovery of a Novel Template, 7-Substituted 7-Deaza-4′-Thioadenosine Derivatives as Multi-Kinase Inhibitors

por Mashelkar, Karishma K., Byun, Woong Sub, Ko, Hyejin, Sung, Kisu, Tripathi, Sushil K., An, Seungchan, Yum, Yun A, Kwon, Jee Youn, Kim, Minjae, Kim, Gibae, Kwon, Eun-Ji, Lee, Hyuk Woo, Noh, Minsoo, Lee, Sang Kook, Jeong, Lak Shin
Publicado 2021

A novel IRAK4/PIM1 inhibitor ameliorates rheumatoid arthritis and lymphoid malignancy by blocking the TLR/MYD88-mediated NF-κB pathway

por Yoon, Sae-Bom, Hong, Hyowon, Lim, Hee-Jong, Choi, Ji Hye, Choi, Yoon Pyo, Seo, Seong Wook, Lee, Hyuk Woo, Chae, Chong Hak, Park, Woo-Kyu, Kim, Hyun Young, Jeong, Daeyoung, De, Tran Quang, Myung, Chang-Seon, Cho, Heeyeong
Publicado 2023

Design, Synthesis, and Anti-RNA Virus Activity of 6′-Fluorinated-Aristeromycin Analogues

por Yoon, Ji-seong, Kim, Gyudong, Jarhad, Dnyandev B., Kim, Hong-Rae, Shin, Young-Sup, Qu, Shuhao, Sahu, Pramod K., Kim, Hea Ok, Lee, Hyuk Woo, Wang, Su Bin, Kong, Yun Jeong, Chang, Tong-Shin, Ogando, Natacha S., Kovacikova, Kristina, Snijder, Eric J., Posthuma, Clara C., van Hemert, Martijn J., Jeong, Lak Shin
Publicado 2019