Findings on In Vitro Transporter-Mediated Drug Interactions and Their Follow-Up Actions for Labeling: Analysis of Drugs Approved by US FDA between 2017 and 2021

por Lee, Kyeong-Ryoon, Chang, Ji-Eun, Yoon, Jongmin, Jin, Hyojeong, Chae, Yoon-Jee
Publicado 2022

Model-Based Prediction of Acid Suppression and Proposal of a New Dosing Regimen of Fexuprazan in Humans

por Kim, Min-Soo, Lee, Nora, Lee, Areum, Chae, Yoon-Jee, Chung, Suk-Jae, Lee, Kyeong-Ryoon
Publicado 2022

A population PK–PD model of YH4808, a novel P‐CAB, and intragastric pH that incorporated negative feedback by increased intragastric pH onto the systemic exposure to YH4808

por Chung, Tae Kyu, Lee, Hyun A., Lee, Kyeong‐Ryoon, Jang, Seong Bok, Yu, Kyung‐Sang, Lee, Howard
Publicado 2022

Pharmacokinetic Estimation Models-based Approach to Predict Clinical Implications for CYP Induction by Calcitriol in Human Cryopreserved Hepatocytes and HepaRG Cells

por Chae, Yoon-Jee, Kim, Min-Soo, Chung, Suk-Jae, Lee, Mi-Kyung, Lee, Kyeong-Ryoon, Maeng, Han-Joo
Publicado 2021

A Machine Learning-Based Identification of Genes Affecting the Pharmacokinetics of Tacrolimus Using the DMET(TM) Plus Platform

por Gim, Jeong-An, Kwon, Yonghan, Lee, Hyun A, Lee, Kyeong-Ryoon, Kim, Soohyun, Choi, Yoonjung, Kim, Yu Kyong, Lee, Howard
Publicado 2020

Development of Physiologically Based Pharmacokinetic Model for Orally Administered Fexuprazan in Humans

por Jeong, Yoo-Seong, Kim, Min-Soo, Lee, Nora, Lee, Areum, Chae, Yoon-Jee, Chung, Suk-Jae, Lee, Kyeong-Ryoon
Publicado 2021

Integration of a Physiologically Based Pharmacokinetic and Pharmacodynamic Model for Tegoprazan and Its Metabolite: Application for Predicting Food Effect and Intragastric pH Alter...

por Jeong, Hyeon-Cheol, Kim, Min-Gul, Wei, Zhuodu, Lee, Kyeong-Ryoon, Lee, Jaehyeok, Song, Im-Sook, Shin, Kwang-Hee
Publicado 2022

Quercetin Is a Flavonoid Breast Cancer Resistance Protein Inhibitor with an Impact on the Oral Pharmacokinetics of Sulfasalazine in Rats

por Song, Yoo-Kyung, Yoon, Jin-Ha, Woo, Jong Kyu, Kang, Ju-Hee, Lee, Kyeong-Ryoon, Oh, Seung Hyun, Chung, Suk-Jae, Maeng, Han-Joo
Publicado 2020

HS-133, a novel fluorescent phosphatidylinositol 3-kinase inhibitor as a potential imaging and anticancer agent for targeted therapy

por Lee, Ju-Hee, Jung, Kyung Hee, Lee, Hyunseung, Son, Mi Kwon, Yun, Sun-Mi, Ahn, Sung-Hoon, Lee, Kyeong-Ryoon, Lee, Soyoung, Kim, Donghee, Hong, Sungwoo, Hong, Soon-Sun
Publicado 2014

Population Pharmacokinetic Method to Predict Within-Subject Variability Using Single-Period Clinical Data

por Kang, Won-ho, Lee, Jae-yeon, Chae, Jung-woo, Lee, Kyeong-Ryoon, Baek, In-hwan, Kim, Min-Soo, Back, Hyun-moon, Jung, Sangkeun, Shaffer, Craig, Savic, Rada, Yun, Hwi-yeol
Publicado 2021

Pharmacokinetic Characterization of Supinoxin and Its Physiologically Based Pharmacokinetic Modeling in Rats

por Song, Yoo-Kyung, Seol, Yun-Hwan, Kim, Min Ju, Jeong, Jong-Woo, Choi, Hae-In, Lee, Seung-Won, Chae, Yoon-Jee, Ahn, Sunjoo, Gong, Young-Dae, Lee, Kyeong-Ryoon, Koo, Tae-Sung
Publicado 2021

Bioanalysis of niclosamide in plasma using liquid chromatography-tandem mass and application to pharmacokinetics in rats and dogs

por Choi, Hae-In, Kim, Taeheon, Lee, Seung-Won, Woo Kim, Jin, Ju Noh, Yoon, Kim, Gwan-Young, Jin Park, Hyun-, Chae, Yoon-Jee, Lee, Kyeong-Ryoon, Kim, Soo-Jin, Koo, Tae-Sung
Publicado 2021

Physiologically Based Pharmacokinetic Modelling to Predict Pharmacokinetics of Enavogliflozin, a Sodium-Dependent Glucose Transporter 2 Inhibitor, in Humans

por Kim, Min-Soo, Song, Yoo-Kyung, Choi, Ji-Soo, Ji, Hye Young, Yang, Eunsuk, Park, Joon Seok, Kim, Hyung Sik, Kim, Min-Joo, Cho, In-Kyung, Chung, Suk-Jae, Chae, Yoon-Jee, Lee, Kyeong-Ryoon
Publicado 2023

In Vivo Toxicity and Pharmacokinetics of Polytetrafluoroethylene Microplastics in ICR Mice

por Lee, Sijoon, Kang, Kyung-Ku, Sung, Soo-Eun, Choi, Joo-Hee, Sung, Minkyoung, Seong, Keum-Yong, Lee, Jian, Kang, Subin, Yang, Seong Yun, Lee, Sunjong, Lee, Kyeong-Ryoon, Seo, Min-Soo, Kim, KilSoo
Publicado 2022

Inhibition of Skin Inflammation by Scytonemin, an Ultraviolet Sunscreen Pigment

por Kang, Moo Rim, Jo, Sun Ah, Lee, Hyunju, Yoon, Yeo Dae, Kwon, Joo-Hee, Yang, Jeong-Wook, Choi, Byeong Jo, Park, Ki Hwan, Lee, Myeong Youl, Lee, Chang Woo, Lee, Kyeong-Ryoon, Kang, Jong Soon
Publicado 2020

Highly specific chimeric DNA-RNA-guided genome editing with enhanced CRISPR-Cas12a system

por Kim, Hanseop, Lee, Wi-jae, Kim, Chan Hyoung, Oh, Yeounsun, Gwon, Lee Wha, Lee, Hyomin, Song, Woojeung, Hur, Junho K., Lim, Kyung-Seob, Jeong, Kang Jin, Nam, Ki-Hoan, Won, Young-Suk, Lee, Kyeong-Ryoon, Lee, Youngjeon, Kim, Young-Hyun, Huh, Jae-Won, Jun, Bong-Hyun, Lee, Dong-Seok, Lee, Seung Hwan
Publicado 2022