Multifaceted Roles of TAK1 Signaling in Cancer

por Mukhopadhyay, Himadri, Lee, Nam Y.
Publicado 2019

Strength and duration of GIPC-dependent signaling networks as determinants in cancer

por Ahmed, Tasmia, Mythreye, Karthikeyan, Lee, Nam Y.
Publicado 2020

A bioinformatic analysis of the inhibin-betaglycan-endoglin/CD105 network reveals prognostic value in multiple solid tumors

por Listik, Eduardo, Horst, Ben, Choi, Alex Seok, Lee, Nam. Y., Győrffy, Balázs, Mythreye, Karthikeyan
Publicado 2021

Endoglin regulates PI3-kinase/Akt trafficking and signaling to alter endothelial capillary stability during angiogenesis

por Lee, Nam Y., Golzio, Christelle, Gatza, Catherine E., Sharma, Arun, Katsanis, Nicholas, Blobe, Gerard C.
Publicado 2012

TGFβ signaling networks in ovarian cancer progression and plasticity

por Kumari, Asha, Shonibare, Zainab, Monavarian, Mehri, Arend, Rebecca C., Lee, Nam Y., Inman, Gareth J., Mythreye, Karthikeyan
Publicado 2021

Beta IV spectrin inhibits the metastatic growth of melanoma by suppressing VEGFR2‐driven tumor angiogenesis

por Kwak, Eun‐A., Ahmed, Tasmia, Flores, Paola Cruz, Ortiz, Hannah R., Langlais, Paul R., Mythreye, Karthikeyan, Lee, Nam Y.
Publicado 2023

Epigenetic Regulation of GDF2 Suppresses Anoikis in Ovarian and Breast Epithelia()

por Varadaraj, Archana, Patel, Pratik, Serrao, Anne, Bandyopadhay, Tirthankar, Lee, Nam Y., Jazaeri, Amir A., Huang, Zhiqing, Murphy, Susan K., Mythreye, Karthikeyan
Publicado 2015

EPDR1 is a noncanonical effector of insulin-mediated angiogenesis regulated by an endothelial-specific TGF-β receptor complex

por Ahmed, Tasmia, Flores, Paola Cruz, Pan, Christopher C., Ortiz, Hannah R., Lee, Yeon S., Langlais, Paul R., Mythreye, Karthikeyan, Lee, Nam Y.
Publicado 2022

TAK1 activation of alpha-TAT1 and microtubule hyperacetylation control AKT signaling and cell growth

por Shah, Nirav, Kumar, Sanjay, Zaman, Naveed, Pan, Christopher C., Bloodworth, Jeffrey C., Lei, Wei, Streicher, John M., Hempel, Nadine, Mythreye, Karthikeyan, Lee, Nam Y.
Publicado 2018

Endothelial tip/stalk cell selection requires BMP9-induced β(IV)-spectrin expression during sprouting angiogenesis

por Ahmed, Tasmia, Ramonett, Aaron, Kwak, Eun-A, Kumar, Sanjay, Flores, Paola Cruz, Ortiz, Hannah R., Langlais, Paul R., Hund, Thomas J., Mythreye, Karthikeyan, Lee, Nam Y.
Publicado 2023

Modulation of circulating protein biomarkers following TRC105 (anti-endoglin antibody) treatment in patients with advanced cancer

por Liu, Yingmiao, Starr, Mark D, Brady, John C, Dellinger, Andrew, Pang, Herbert, Adams, Bonne, Theuer, Charles P, Lee, Nam Y, Hurwitz, Herbert I, Nixon, Andrew B
Publicado 2014

Angiostatic actions of capsicodendrin through selective inhibition of VEGFR2-mediated AKT signaling and disregulated autophagy

por Pan, Christopher C., Shah, Nirav, Kumar, Sanjay, Wheeler, Sarah E., Cinti, Jason, Hoyt, Dale G., Beattie, Christine E., An, Min, Mythreye, Karthikeyan, Rakotondraibe, L. Harinantenaina, Lee, Nam Y.
Publicado 2016

Regulation of mitochondrial fission by GIPC-mediated Drp1 retrograde transport

por Ramonett, Aaron, Kwak, Eun-A, Ahmed, Tasmia, Flores, Paola Cruz, Ortiz, Hannah R., Lee, Yeon Sun, Vanderah, Todd W., Largent-Milnes, Tally, Kashatus, David F., Langlais, Paul R., Mythreye, Karthikeyan, Lee, Nam Y.
Publicado 2022

Hypoxia-induced inhibin promotes tumor growth and vascular permeability in ovarian cancers

por Horst, Ben, Pradhan, Shrikant, Chaudhary, Roohi, Listik, Eduardo, Quintero-Macias, Liz, Choi, Alex Seok, Southard, Michael, Liu, Yingmiao, Whitaker, Regina, Hempel, Nadine, Berchuck, Andrew, Nixon, Andrew B., Lee, Nam Y., Henis, Yoav I., Mythreye, Karthikeyan
Publicado 2022

Reciprocal SOX2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer

por Shonibare, Zainab, Monavarian, Mehri, O’Connell, Kathleen, Altomare, Diego, Shelton, Abigail, Mehta, Shubham, Jaskula-Sztul, Renata, Phaeton, Rebecca, Starr, Mark D., Whitaker, Regina, Berchuck, Andrew, Nixon, Andrew B., Arend, Rebecca C., Lee, Nam Y., Miller, C. Ryan, Hempel, Nadine, Mythreye, Karthikeyan
Publicado 2022

GPx3 supports ovarian cancer progression by manipulating the extracellular redox environment

por Worley, Beth L., Kim, Yeon Soo, Mardini, Jennifer, Zaman, Rameez, Leon, Kelly E., Vallur, Piyushi Gupta, Nduwumwami, Asvelt, Warrick, Joshua I., Timmins, Patrick F., Kesterson, Joshua P., Phaëton, Rébécca, Lee, Nam Y., Walter, Vonn, Endres, Lauren, Mythreye, Karthikeyan, Aird, Katherine M., Hempel, Nadine
Publicado 2018

Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells

por Kim, Yeon Soo, Vallur, Piyushi Gupta, Jones, Victoria M., Worley, Beth L., Shimko, Sara, Shin, Dong-Hui, Crawford, LaTaijah C., Chen, Chi-Wei, Aird, Katherine M., Abraham, Thomas, Shepherd, Trevor G., Warrick, Joshua I., Lee, Nam Y., Phaeton, Rebecca, Mythreye, Karthikeyan, Hempel, Nadine
Publicado 2019

β(IV)-spectrin as a stalk cell-intrinsic regulator of VEGF signaling

por Kwak, Eun-A, Pan, Christopher C., Ramonett, Aaron, Kumar, Sanjay, Cruz-Flores, Paola, Ahmed, Tasmia, Ortiz, Hannah R., Lochhead, Jeffrey J., Ellis, Nathan A., Mouneimne, Ghassan, Georgieva, Teodora G., Lee, Yeon Sun, Vanderah, Todd W., Largent-Milnes, Tally, Mohler, Peter J., Hund, Thomas J., Langlais, Paul R., Mythreye, Karthikeyan, Lee, Nam Y.
Publicado 2022