Losing p53 loosens up ER-stress

por Byun, Sanguine, Namba, Takushi, Lee, Sam W.
Publicado 2015

Comparative Analysis of P73 and P53 Regulation and Effector Functions

por Fang, Li, Lee, Sam W., Aaronson, Stuart A.
Publicado 1999

Structural Mechanisms Determining Inhibition of the Collagen Receptor DDR1 by Selective and Multi-Targeted Type II Kinase Inhibitors

por Canning, Peter, Tan, Li, Chu, Kiki, Lee, Sam W., Gray, Nathanael S., Bullock, Alex N.
Publicado 2014

Induced cancer stem-like cells as a model for biological screening and discovery of agents targeting phenotypic traits of cancer stem cell

por Nishi, Mayuko, Akutsu, Hidenori, Kudoh, Ayumi, Kimura, Hirokazu, Yamamoto, Naoki, Umezawa, Akihiro, Lee, Sam W., Ryo, Akihide
Publicado 2014

Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway

por Namba, Takushi, Chu, Kiki, Kodama, Rika, Byun, Sanguine, Yoon, Kyoung Wan, Hiraki, Masatsugu, Mandinova, Anna, Lee, Sam W.
Publicado 2015

Transcriptional role of p53 in interferon-mediated antiviral immunity

por Muñoz-Fontela, César, Macip, Salvador, Martínez-Sobrido, Luis, Brown, Lauren, Ashour, Joseph, García-Sastre, Adolfo, Lee, Sam W., Aaronson, Stuart A.
Publicado 2008

Identification of ROCK1 kinase as a critical regulator of Beclin1 mediated autophagy during metabolic stress

por Gurkar, Aditi U., Chu, Kiki, Raj, Lakshmi, Bouley, Richard, Lee, Seung-Hwan, Kim, Young-Bum, Dunn, Sandra E., Mandinova, Anna, Lee, Sam W.
Publicado 2013

The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level

por Kwon, Eunjeong, Todorova, Kristina, Wang, Jun, Horos, Rastislav, Lee, Kevin K., Neel, Victor A., Negri, Gian Luca, Sorensen, Poul H., Lee, Sam W., Hentze, Matthias W., Mandinova, Anna
Publicado 2018

Clinical and research updates on the VISTA immune checkpoint: immuno-oncology themes and highlights

por Noelle, Randolph J., Lines, J. Louise, Lewis, Lionel D., Martell, Robert E., Guillaudeux, Thierry, Lee, Sam W., Mahoney, Kathleen M., Vesely, Matthew D., Boyd-Kirkup, Jerome, Nambiar, Dhanya K., Scott, Andrew M.
Publicado 2023

Correction to Discovery of a Potent and Selective DDR1 Receptor Tyrosine Kinase Inhibitor

por Kim, Hyung-Gu, Tan, Li, Weisberg, Ellen L., Liu, Feiyang, Canning, Peter, Choi, Hwan-Geun, Ezell, Scott, Zhao, Zheng, Wu, Hong, Wang, Jinhua, Mandinova, Anna, Bullock, Alex N., Liu, Qingsong, Lee, Sam W., Gray, Nathanael S.
Publicado 2014

Selective killing of cancer cells with a small molecule targeting stress response to ROS

por Raj, Lakshmi, Ide, Takao, Gurkar, Aditi U, Foley, Michael, Schenone, Monica, Li, Xiaoyu, Tolliday, Nicola J., Golub, Todd R., Carr, Steven A., Shamji, Alykhan F., Stern, Andrew M., Mandinova, Anna, Schreiber, Stuart L., Lee, Sam W.
Publicado 2011

Rho-kinase Regulates Energy Balance by Targeting Hypothalamic Leptin Receptor Signaling

por Huang, Hu, Kong, Dong, Byun, Kyung Hee, Ye, Chianping, Koda, Shuichi, Lee, Dae Ho, Oh, Byung-Chul, Lee, Sam W, Lee, Bonghee, Zabolotny, Janice M, Kim, Min Seon, Bjørbæk, Christian, Lowell, Bradford B, Kim, Young-Bum
Publicado 2012

VISTA regulates microglia homeostasis and myelin phagocytosis, and is associated with MS lesion pathology

por Borggrewe, Malte, Kooistra, Susanne M., Wesseling, Evelyn M., Gierschek, Fenja L., Brummer, Maaike L., Nowak, Elizabeth C., Medeiros-Furquim, Tiago, Otto, Tegan A., Lee, Sam W., Noelle, Randolph J., Eggen, Bart J. L., Laman, Jon D.
Publicado 2021

Discovery of a Potent and Selective DDR1 Receptor Tyrosine Kinase Inhibitor

por Kim, Hyung-Gu, Tan, Li, Weisberg, Ellen L., Liu, Feiyang, Canning, Peter, Choi, Hwan Geun, Ezell, Scott A., Wu, Hong, Zhao, Zheng, Wang, Jinhua, Mandinova, Anna, Griffin, James D., Bullock, Alex N., Liu, Qingsong, Lee, Sam W., Gray, Nathanael S.
Publicado 2013

A small molecule that binds Hedgehog and blocks its signaling in human cells

por Stanton, Benjamin Z., Peng, Lee F., Maloof, Nicole, Nakai, Kazuo, Wang, Xiang, Herlihy, Kara M., Duffner, Jay L., Taveras, Kennedy M., Hyman, Joel M., Lee, Sam W., Koehler, Angela N., Chen, James K., Fox, Julia L., Mandinova, Anna, Schreiber, Stuart L.
Publicado 2009

Synthetic lethality by targeting the RUVBL1/2-TTT complex in mTORC1-hyperactive cancer cells

por Shin, Seung Ho, Lee, Ji Su, Zhang, Jia-Min, Choi, Sungbin, Boskovic, Zarko V., Zhao, Ran, Song, Mengqiu, Wang, Rui, Tian, Jie, Lee, Mee-Hyun, Kim, Jae Hwan, Jeong, Minju, Lee, Jung Hyun, Petukhov, Michael, Lee, Sam W., Kim, Sang Gyun, Zou, Lee, Byun, Sanguine
Publicado 2020

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

por Galluzzi, Lorenzo, Vitale, Ilio, Aaronson, Stuart A., Abrams, John M., Adam, Dieter, Agostinis, Patrizia, Alnemri, Emad S., Altucci, Lucia, Amelio, Ivano, Andrews, David W., Annicchiarico-Petruzzelli, Margherita, Antonov, Alexey V., Arama, Eli, Baehrecke, Eric H., Barlev, Nickolai A., Bazan, Nicolas G., Bernassola, Francesca, Bertrand, Mathieu J. M., Bianchi, Katiuscia, Blagosklonny, Mikhail V., Blomgren, Klas, Borner, Christoph, Boya, Patricia, Brenner, Catherine, Campanella, Michelangelo, Candi, Eleonora, Carmona-Gutierrez, Didac, Cecconi, Francesco, Chan, Francis K.-M., Chandel, Navdeep S., Cheng, Emily H., Chipuk, Jerry E., Cidlowski, John A., Ciechanover, Aaron, Cohen, Gerald M., Conrad, Marcus, Cubillos-Ruiz, Juan R., Czabotar, Peter E., D’Angiolella, Vincenzo, Dawson, Ted M., Dawson, Valina L., De Laurenzi, Vincenzo, De Maria, Ruggero, Debatin, Klaus-Michael, DeBerardinis, Ralph J., Deshmukh, Mohanish, Di Daniele, Nicola, Di Virgilio, Francesco, Dixit, Vishva M., Dixon, Scott J., Duckett, Colin S., Dynlacht, Brian D., El-Deiry, Wafik S., Elrod, John W., Fimia, Gian Maria, Fulda, Simone, García-Sáez, Ana J., Garg, Abhishek D., Garrido, Carmen, Gavathiotis, Evripidis, Golstein, Pierre, Gottlieb, Eyal, Green, Douglas R., Greene, Lloyd A., Gronemeyer, Hinrich, Gross, Atan, Hajnoczky, Gyorgy, Hardwick, J. Marie, Harris, Isaac S., Hengartner, Michael O., Hetz, Claudio, Ichijo, Hidenori, Jäättelä, Marja, Joseph, Bertrand, Jost, Philipp J., Juin, Philippe P., Kaiser, William J., Karin, Michael, Kaufmann, Thomas, Kepp, Oliver, Kimchi, Adi, Kitsis, Richard N., Klionsky, Daniel J., Knight, Richard A., Kumar, Sharad, Lee, Sam W., Lemasters, John J., Levine, Beth, Linkermann, Andreas, Lipton, Stuart A., Lockshin, Richard A., López-Otín, Carlos, Lowe, Scott W., Luedde, Tom, Lugli, Enrico, MacFarlane, Marion, Madeo, Frank, Malewicz, Michal, Malorni, Walter, Manic, Gwenola, Marine, Jean-Christophe, Martin, Seamus J., Martinou, Jean-Claude, Medema, Jan Paul, Mehlen, Patrick, Meier, Pascal, Melino, Sonia, Miao, Edward A., Molkentin, Jeffery D., Moll, Ute M., Muñoz-Pinedo, Cristina, Nagata, Shigekazu, Nuñez, Gabriel, Oberst, Andrew, Oren, Moshe, Overholtzer, Michael, Pagano, Michele, Panaretakis, Theocharis, Pasparakis, Manolis, Penninger, Josef M., Pereira, David M., Pervaiz, Shazib, Peter, Marcus E., Piacentini, Mauro, Pinton, Paolo, Prehn, Jochen H.M., Puthalakath, Hamsa, Rabinovich, Gabriel A., Rehm, Markus, Rizzuto, Rosario, Rodrigues, Cecilia M.P., Rubinsztein, David C., Rudel, Thomas, Ryan, Kevin M., Sayan, Emre, Scorrano, Luca, Shao, Feng, Shi, Yufang, Silke, John, Simon, Hans-Uwe, Sistigu, Antonella, Stockwell, Brent R., Strasser, Andreas, Szabadkai, Gyorgy, Tait, Stephen W.G., Tang, Daolin, Tavernarakis, Nektarios, Thorburn, Andrew, Tsujimoto, Yoshihide, Turk, Boris, Vanden Berghe, Tom, Vandenabeele, Peter, Vander Heiden, Matthew G., Villunger, Andreas, Virgin, Herbert W., Vousden, Karen H., Vucic, Domagoj, Wagner, Erwin F., Walczak, Henning, Wallach, David, Wang, Ying, Wells, James A., Wood, Will, Yuan, Junying, Zakeri, Zahra, Zhivotovsky, Boris, Zitvogel, Laurence, Melino, Gerry, Kroemer, Guido
Publicado 2018