Transmission of alpha-synuclein in Parkinson’s disease

por Lee, Virginia M-Y
Publicado 2013

Manipulation of the diet–microbiota–brain axis in Alzheimer’s disease

por Lee, Daniel, Lee, Virginia M-Y., Hur, Seong Kwon
Publicado 2022

Detection of a Novel Intraneuronal Pool of Insoluble Amyloid β Protein that Accumulates with Time in Culture

por Skovronsky, Daniel M., Doms, Robert W., Lee, Virginia M.-Y.
Publicado 1998

Drosha Inclusions Are New Components of Dipeptide-Repeat Protein Aggregates in FTLD-TDP and ALS C9orf72 Expansion Cases

por Porta, Sílvia, Kwong, Linda K., Trojanowski, John Q., Lee, Virginia M.-Y.
Publicado 2015

LRRK2 activity does not dramatically alter α-synuclein pathology in primary neurons

por Henderson, Michael X., Peng, Chao, Trojanowski, John Q., Lee, Virginia M. Y.
Publicado 2018

Alzheimer’s disease tau is a prominent pathology in LRRK2 Parkinson’s disease

por Henderson, Michael X., Sengupta, Medha, Trojanowski, John Q., Lee, Virginia M. Y.
Publicado 2019

LRRK2 Kinase Activity Does Not Alter Cell-Autonomous Tau Pathology Development in Primary Neurons

por Henderson, Michael X., Changolkar, Lakshmi, Trojanowski, John Q., Lee, Virginia M.Y.
Publicado 2021

Identification of small molecules and related targets that modulate tau pathology in a seeded primary neuron model

por Gibbons, Garrett S., Gould, Hailey, Lee, Virginia M.-Y., Crowe, Alex, Brunden, Kurt R.
Publicado 2023

Brain Microvascular Pericytes in Vascular Cognitive Impairment and Dementia

por Uemura, Maiko T., Maki, Takakuni, Ihara, Masafumi, Lee, Virginia M. Y., Trojanowski, John Q.
Publicado 2020

Neurofilaments and Orthograde Transport Are Reduced in Ventral Root Axons of Transgenic Mice that Express Human SOD1 with a G93A Mutation

por Zhang, Bin, Tu, Pang-hsien, Abtahian, Farhad, Trojanowski, John Q., Lee, Virginia M.-Y.
Publicado 1997

Novel β-Secretase Cleavage of β-Amyloid Precursor Protein in the Endoplasmic Reticulum/Intermediate Compartment of NT2N Cells

por Chyung, Abraham S.C., Greenberg, Barry D., Cook, David G., Doms, Robert W., Lee, Virginia M.-Y.
Publicado 1997

Degradative organelles containing mislocalized α- and β-synuclein proliferate in presenilin-1 null neurons

por Wilson, Christina A., Murphy, Diane D., Giasson, Benoit I., Zhang, Bin, Trojanowski, John Q., Lee, Virginia M.-Y.
Publicado 2004

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice

por Luk, Kelvin C., Kehm, Victoria M., Zhang, Bin, O’Brien, Patrick, Trojanowski, John Q., Lee, Virginia M.Y.
Publicado 2012

Fluent molecular mixing of Tau isoforms in Alzheimer’s disease neurofibrillary tangles

por Dregni, Aurelio J., Duan, Pu, Xu, Hong, Changolkar, Lakshmi, El Mammeri, Nadia, Lee, Virginia M.-Y., Hong, Mei
Publicado 2022

Conserved Lysine Acetylation within the Microtubule-Binding Domain Regulates MAP2/Tau Family Members

por Hwang, Andrew W., Trzeciakiewicz, Hanna, Friedmann, Dave, Yuan, Chao-Xing, Marmorstein, Ronen, Lee, Virginia M. Y., Cohen, Todd J.
Publicado 2016

Inhibition of CK2 mitigates Alzheimer’s tau pathology by preventing NR2B synaptic mislocalization

por Marshall, Courtney A., McBride, Jennifer D., Changolkar, Lakshmi, Riddle, Dawn M., Trojanowski, John Q., Lee, Virginia M.-Y.
Publicado 2022

Evaluation of blood‐based, extracellular vesicles as biomarkers for aging‐related TDP‐43 pathology

por Winston, Charisse N., Sukreet, Sonal, Lynch, Haley, Lee, Virginia M.‐Y., Wilcock, Donna M., Nelson, Peter T., Rissman, Robert A.
Publicado 2022

BACE overexpression alters the subcellular processing of APP and inhibits Aβ deposition in vivo

por Lee, Edward B., Zhang, Bin, Liu, Kangning, Greenbaum, Eric A., Doms, Robert W., Trojanowski, John Q., Lee, Virginia M.-Y.
Publicado 2005

Formation of α-synuclein Lewy neurite–like aggregates in axons impedes the transport of distinct endosomes

por Volpicelli-Daley, Laura A., Gamble, Karen L., Schultheiss, Christine E., Riddle, Dawn M., West, Andrew B., Lee, Virginia M.-Y.
Publicado 2014

α-Synuclein Immunotherapy Blocks Uptake and Templated Propagation of Misfolded α-Synuclein and Neurodegeneration

por Tran, Hien T., Chung, Charlotte Hiu-Yan, Iba, Michiyo, Zhang, Bin, Trojanowski, John Q., Luk, Kelvin C., Lee, Virginia M.Y.
Publicado 2014