Open Access Target Validation Is a More Efficient Way to Accelerate Drug Discovery

por Lee, Wen Hwa
Publicado 2015

Accelerating target discovery using pre-competitive open science—patients need faster innovation more than anyone else

por Low, Eric, Bountra, Chas, Lee, Wen Hwa
Publicado 2016

Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint

por Wei, Randy, Ngo, Bryan, Wu, Guikai, Lee, Wen-Hwa
Publicado 2011

Targeting interleukin-17 receptors

por Lee, Wen-Hwa, Wu, Heng-Hsiung, Huang, Chun-Kai
Publicado 2015

Hypoxia, Epithelial-Mesenchymal Transition, and TET-Mediated Epigenetic Changes

por Kao, Shih-Han, Wu, Kou-Juey, Lee, Wen-Hwa
Publicado 2016

Establishing a reliable framework for harnessing the creative power of the scientific crowd

por Carter, Adrian J., Donner, Amy, Lee, Wen Hwa, Bountra, Chas
Publicado 2017

SGC - Structural Biology and Human Health: A New Approach to Publishing Structural Biology Results

por Lee, Wen Hwa, Atienza-Herrero, Julián, Abagyan, Ruben, Marsden, Brian D.
Publicado 2009

Biomarkers to Target Heterogeneous Breast Cancer Stem Cells

por Hwang-Verslues, Wendy W., Lee, Wen-Hwa, Lee, Eva Y.-H.P.
Publicado 2012

Interplays of glucose metabolism and KRAS mutation in pancreatic ductal adenocarcinoma

por Liu, Yu-Huei, Hu, Chun-Mei, Hsu, Yuan-Sheng, Lee, Wen-Hwa
Publicado 2022

Inhibitory Member of the Apoptosis-stimulating Proteins of the p53 Family (iASPP) Interacts with Protein Phosphatase 1 via a Noncanonical Binding Motif

por Llanos, Susana, Royer, Christophe, Lu, Min, Bergamaschi, Daniele, Lee, Wen Hwa, Lu, Xin
Publicado 2011

Non-targeting siRNA induces NPGPx expression to cooperate with exoribonuclease XRN2 for releasing the stress

por Wei, Pei-Chi, Lo, Wen-Ting, Su, Mei-I., Shew, Jin-Yuh, Lee, Wen-Hwa
Publicado 2012

NPGPx modulates CPEB2-controlled HIF-1α RNA translation in response to oxidative stress

por Chen, Po-Jen, Weng, Jui-Yun, Hsu, Pang-Hung, Shew, Jin-Yuh, Huang, Yi-Shuian, Lee, Wen-Hwa
Publicado 2015

Structure of the CaMKIIδ/Calmodulin Complex Reveals the Molecular Mechanism of CaMKII Kinase Activation

por Rellos, Peter, Pike, Ashley C. W., Niesen, Frank H., Salah, Eidarus, Lee, Wen Hwa, von Delft, Frank, Knapp, Stefan
Publicado 2010

Structural genomics of histone tail recognition

por Wang, Minghua, Mok, Man Wai, Harper, Hong, Lee, Wen Hwa, Min, Jinrong, Knapp, Stefan, Oppermann, Udo, Marsden, Brian, Schapira, Matthieu
Publicado 2010

Structural basis of fumarate hydratase deficiency

por Picaud, Sarah, Kavanagh, Kathryn L., Yue, Wyatt W., Lee, Wen Hwa, Muller-Knapp, Susanne, Gileadi, Opher, Sacchettini, James, Oppermann, Udo
Publicado 2011

A structural mapping of mutations causing succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency

por Shafqat, Naeem, Kavanagh, Kate L., Sass, Jörn Oliver, Christensen, Ernst, Fukao, Toshiyuki, Lee, Wen Hwa, Oppermann, Udo, Yue, Wyatt W.
Publicado 2013

A cis-element with mixed G-quadruplex structure of NPGPx promoter is essential for nucleolin-mediated transactivation on non-targeting siRNA stress

por Wei, Pei-Chi, Wang, Zi-Fu, Lo, Wen-Ting, Su, Mei-I, Shew, Jin-Yuh, Chang, Ta-Chau, Lee, Wen-Hwa
Publicado 2013

Crystal Structures of the p21-Activated Kinases PAK4, PAK5, and PAK6 Reveal Catalytic Domain Plasticity of Active Group II PAKs

por Eswaran, Jeyanthy, Lee, Wen Hwa, Debreczeni, Judit É., Filippakopoulos, Panagis, Turnbull, Andrew, Fedorov, Oleg, Deacon, Sean W., Peterson, Jeffrey R., Knapp, Stefan
Publicado 2007

Comparative Structural Analysis of Lipid Binding START Domains

por Thorsell, Ann-Gerd, Lee, Wen Hwa, Persson, Camilla, Siponen, Marina I., Nilsson, Martina, Busam, Robert D., Kotenyova, Tetyana, Schüler, Herwig, Lehtiö, Lari
Publicado 2011

Structural Comparison of Human Mammalian Ste20-Like Kinases

por Record, Christopher J., Chaikuad, Apirat, Rellos, Peter, Das, Sanjan, Pike, Ashley C. W., Fedorov, Oleg, Marsden, Brian D., Knapp, Stefan, Lee, Wen Hwa
Publicado 2010