Global Protein Conjugation by Ubiquitin-Like-Modifiers during Ischemic Stress Is Regulated by MicroRNAs and Confers Robust Tolerance to Ischemia

por Lee, Yang-ja, Johnson, Kory R., Hallenbeck, John M.
Publicado 2012

Akt Protein Kinase, miR-200/miR-182 Expression and Epithelial-Mesenchymal Transition Proteins in Hibernating Ground Squirrels

por Lee, Yang-ja, Bernstock, Joshua D., Klimanis, Dace, Hallenbeck, John M.
Publicado 2018

Global SUMOylation is a molecular mechanism underlying hypothermia-induced ischemic tolerance

por Lee, Yang-ja, Mou, Yongshan, Klimanis, Dace, Bernstock, Joshua D., Hallenbeck, John M.
Publicado 2014

Elevated Global SUMOylation in Ubc9 Transgenic Mice Protects Their Brains against Focal Cerebral Ischemic Damage

por Lee, Yang-ja, Mou, Yongshan, Maric, Dragan, Klimanis, Dace, Auh, Sungyoung, Hallenbeck, John M.
Publicado 2011

Drugging SUMOylation for neuroprotection and oncotherapy

por Bernstock, Joshua D., Ye, Daniel G., Lee, Yang-ja, Gessler, Florian, Friedman, Gregory K., Zheng, Wei, Hallenbeck, John M.
Publicado 2018

Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis

por Karbowski, Mariusz, Lee, Yang-Ja, Gaume, Brigitte, Jeong, Seon-Yong, Frank, Stephan, Nechushtan, Amotz, Santel, Ansgar, Fuller, Margaret, Smith, Carolyn L., Youle, Richard J.
Publicado 2002

Cerebral Ischemia Increases Small Ubiquitin-Like Modifier Conjugation within Human Penumbral Tissue: Radiological–Pathological Correlation

por Bernstock, Joshua D., Ye, Daniel G., Griffin, Allison, Lee, Yang-ja, Lynch, John, Latour, Lawrence L., Friedman, Gregory K., Maric, Dragan, Hallenbeck, John M.
Publicado 2018

A novel quantitative high-throughput screen identifies drugs that both activate SUMO conjugation via the inhibition of microRNAs 182 and 183 and facilitate neuroprotection in a mod...

por Bernstock, Joshua D, Lee, Yang-ja, Peruzzotti-Jametti, Luca, Southall, Noel, Johnson, Kory R, Maric, Dragan, Volpe, Giulio, Kouznetsova, Jennifer, Zheng, Wei, Pluchino, Stefano, Hallenbeck, John M
Publicado 2015

Topotecan is a potent inhibitor of SUMOylation in glioblastoma multiforme and alters both cellular replication and metabolic programming

por Bernstock, Joshua D., Ye, Daniel, Gessler, Florian A., Lee, Yang-ja, Peruzzotti-Jametti, Luca, Baumgarten, Peter, Johnson, Kory R., Maric, Dragan, Yang, Wei, Kögel, Donat, Pluchino, Stefano, Hallenbeck, John M.
Publicado 2017

SUMOylation promotes survival and integration of neural stem cell grafts in ischemic stroke

por Bernstock, Joshua D., Peruzzotti-Jametti, Luca, Leonardi, Tommaso, Vicario, Nunzio, Ye, Daniel, Lee, Yang-ja, Maric, Dragan, Johnson, Kory R., Mou, Yongshan, Van Den Bosch, Aletta, Winterbone, Mark, Friedman, Gregory K., Franklin, Robin J.M., Hallenbeck, John M., Pluchino, Stefano
Publicado 2019