RX-3117 (Fluorocyclopentenyl-Cytosine)-Mediated Down-Regulation of DNA Methyltransferase 1 Leads to Protein Expression of Tumor-Suppressor Genes and Increased Functionality of the...

por Sarkisjan, Dzjemma, Julsing, Joris R., El Hassouni, Btissame, Honeywell, Richard J., Kathmann, Ietje, Matherly, Larry H., Lee, Young B., Kim, Deog J., Peters, Godefridus J.
Publicado 2020

The Cytidine Analog Fluorocyclopentenylcytosine (RX-3117) Is Activated by Uridine-Cytidine Kinase 2

por Sarkisjan, Dzjemma, Julsing, Joris R., Smid, Kees, de Klerk, Daniël, van Kuilenburg, André B. P., Meinsma, Rutger, Lee, Young B., Kim, Deog J., Peters, Godefridus J.
Publicado 2016

RX-5902, a novel β-catenin modulator, potentiates the efficacy of immune checkpoint inhibitors in preclinical models of triple-negative breast Cancer

por Tentler, John J., Lang, Julie, Capasso, Anna, Kim, Deog Joong, Benaim, Ely, Lee, Young B., Eisen, Andrew, Bagby, Stacey M., Hartman, Sarah J., Yacob, Betelehem W., Gittleman, Brian, Pitts, Todd M., Pelanda, Roberta, Eckhardt, S. Gail, Diamond, Jennifer R.
Publicado 2020