Inadequate Activation of γδT- and B-cells in Patient with Wiskott-Aldrich Syndrome (WAS) Portrayed by TRG and IGH Repertoire Analyses

por Palevski, Dahlia, Simon, Amos, Lev, Atar, Somech, Raz, Lee, Yu Nee
Publicado 2022

Novel NHEJ1 pathogenic variant linked to severe combined immunodeficiency, microcephaly, and abnormal T and B cell receptor repertoires

por Frizinsky, Shirly, Rechavi, Erez, Barel, Ortal, Lee, Yu Nee, Simon, Amos J., Lev, Atar, Stauber, Tali, Adam, Etai, Somech, Raz
Publicado 2022

CRISPR-Cas9 engineering of the RAG2 locus via complete coding sequence replacement for therapeutic applications

por Allen, Daniel, Knop, Orli, Itkowitz, Bryan, Kalter, Nechama, Rosenberg, Michael, Iancu, Ortal, Beider, Katia, Lee, Yu Nee, Nagler, Arnon, Somech, Raz, Hendel, Ayal
Publicado 2023

Rapid generation of novel models of RAG1 deficiency by CRISPR/Cas9-induced mutagenesis in murine zygotes

por de Bruin, Lisa Ott, Yang, Wei, Capuder, Kelly, Lee, Yu Nee, Antolini, Maddalena, Meyers, Robin, Gellert, Martin, Musunuru, Kiran, Manis, John, Notarangelo, Luigi
Publicado 2016

Multiplex HDR for disease and correction modeling of SCID by CRISPR genome editing in human HSPCs

por Iancu, Ortal, Allen, Daniel, Knop, Orli, Zehavi, Yonathan, Breier, Dor, Arbiv, Adaya, Lev, Atar, Lee, Yu Nee, Beider, Katia, Nagler, Arnon, Somech, Raz, Hendel, Ayal
Publicado 2022

Alterations in T and B Cell Receptor Repertoires Patterns in Patients With IL10 Signaling Defects and History of Infantile-Onset IBD

por Werner, Lael, Lee, Yu Nee, Rechavi, Erez, Lev, Atar, Yerushalmi, Baruch, Ling, Galina, Shah, Neil, Uhlig, Holm H., Weiss, Batia, Somech, Raz, Snapper, Scott B., Shouval, Dror S.
Publicado 2020

Reduced Function and Diversity of T Cell Repertoire and Distinct Clinical Course in Patients With IL7RA Mutation

por Lev, Atar, Simon, Amos J., Barel, Ortal, Eyal, Eran, Glick-Saar, Efrat, Nayshool, Omri, Birk, Ohad, Stauber, Tali, Hochberg, Amit, Broides, Arnon, Almashanu, Shlomo, Hendel, Ayal, Lee, Yu Nee, Somech, Raz
Publicado 2019

Next Generation Sequencing Reveals Skewing of the T and B Cell Receptor Repertoires in Patients with Wiskott–Aldrich Syndrome

por O’Connell, Amy E., Volpi, Stefano, Dobbs, Kerry, Fiorini, Claudia, Tsitsikov, Erdyni, de Boer, Helen, Barlan, Isil B., Despotovic, Jenny M., Espinosa-Rosales, Francisco J., Hanson, I. Celine, Kanariou, Maria G., Martínez-Beckerat, Roxana, Mayorga-Sirera, Alvaro, Mejia-Carvajal, Carmen, Radwan, Nesrine, Weiss, Aaron R., Pai, Sung-Yun, Lee, Yu Nee, Notarangelo, Luigi D.
Publicado 2014

Inherited SLP76 deficiency in humans causes severe combined immunodeficiency, neutrophil and platelet defects

por Lev, Atar, Lee, Yu Nee, Sun, Guangping, Hallumi, Enas, Simon, Amos J., Zrihen, Keren S., Levy, Shiran, Beit Halevi, Tal, Papazian, Maria, Shwartz, Neta, Somekh, Ido, Levy-Mendelovich, Sarina, Wolach, Baruch, Gavrieli, Ronit, Vernitsky, Helly, Barel, Ortal, Javasky, Elisheva, Stauber, Tali, Ma, Chi A., Zhang, Yuan, Amariglio, Ninette, Rechavi, Gideon, Hendel, Ayal, Yablonski, Deborah, Milner, Joshua D., Somech, Raz
Publicado 2020

An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia

por Geron, Ifat, Savino, Angela Maria, Fishman, Hila, Tal, Noa, Brown, John, Turati, Virginia A., James, Chela, Sarno, Jolanda, Hameiri-Grossman, Michal, Lee, Yu Nee, Rein, Avigail, Maniriho, Hillary, Birger, Yehudit, Zemlyansky, Anna, Muler, Inna, Davis, Kara L., Marcu-Malina, Victoria, Mattson, Nicole, Parnas, Oren, Wagener, Rabea, Fischer, Ute, Barata, João T., Jamieson, Catriona H. M., Müschen, Markus, Chen, Chun-Wei, Borkhardt, Arndt, Kirsch, Ilan Richard, Nagler, Arnon, Enver, Tariq, Izraeli, Shai
Publicado 2022