PERK prevents hepatic lipotoxicity by activating the p62-ULK1 axis-mediated noncanonical KEAP1-Nrf2 pathway

por Lee, Da Hyun, Park, Jeong Su, Lee, Yu Seol, Bae, Soo Han
Publicado 2022

The hypertension drug, verapamil, activates Nrf2 by promoting p62-dependent autophagic Keap1 degradation and prevents acetaminophen-induced cytotoxicity

por Lee, Da Hyun, Park, Jeong Su, Lee, Yu Seol, Sung, Su Haeng, Lee, Yong-ho, Bae, Soo Han
Publicado 2017

The Antidiabetic Drug Lobeglitazone Protects Mice From Lipogenesis-Induced Liver Injury via Mechanistic Target of Rapamycin Complex 1 Inhibition

por Lee, Yu Seol, Park, Jeong Su, Lee, Da Hyun, Lee, Dong-Kyu, Kwon, Sung Won, Lee, Byung-Wan, Bae, Soo Han
Publicado 2018

Lysosomal Ca(2+)-mediated TFEB activation modulates mitophagy and functional adaptation of pancreatic β-cells to metabolic stress

por Park, Kihyoun, Lim, Hyejin, Kim, Jinyoung, Hwang, Yeseong, Lee, Yu Seol, Bae, Soo Han, Kim, Hyeongseok, Kim, Hail, Kang, Shin-Wook, Kim, Joo Young, Lee, Myung-Shik
Publicado 2022

Inactivation of Sirtuin2 protects mice from acetaminophen-induced liver injury: possible involvement of ER stress and S6K1 activation

por Lee, Da Hyun, Lee, Buhyun, Park, Jeong Su, Lee, Yu Seol, Kim, Jin Hee, Cho, Yejin, Jo, Yoonjung, Kim, Hyun-Seok, Lee, Yong-ho, Nam, Ki Taek, Bae, Soo Han
Publicado 2019

Co-administration of ursodeoxycholic acid with rosuvastatin/ezetimibe in a non-alcoholic fatty liver disease model

por Seo, Sang Hyun, Lee, Da Hyun, Lee, Yu Seol, Cho, Kyung Joo, Park, Hye Jung, Lee, Hye Won, Kim, Beom Kyung, Park, Jun Yong, Kim, Do Young, Ahn, Sang Hoon, Bae, Soo Han, Kim, Seung Up
Publicado 2022