Response to comment on 'Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity'

por Goldhamer, David J, Lees-Shepard, John B
Publicado 2019

Palovarotene reduces heterotopic ossification in juvenile FOP mice but exhibits pronounced skeletal toxicity

por Lees-Shepard, John B, Nicholas, Sarah-Anne E, Stoessel, Sean J, Devarakonda, Parvathi M, Schneider, Michael J, Yamamoto, Masakazu, Goldhamer, David J
Publicado 2018

An anti-ACVR1 antibody exacerbates heterotopic ossification by fibro-adipogenic progenitors in fibrodysplasia ossificans progressiva mice

por Lees-Shepard, John B., Stoessel, Sean J., Chandler, Julian T., Bouchard, Keith, Bento, Patricia, Apuzzo, Lorraine N., Devarakonda, Parvathi M., Hunter, Jeffrey W., Goldhamer, David J.
Publicado 2022

Activin-dependent signaling in fibro/adipogenic progenitors causes fibrodysplasia ossificans progressiva

por Lees-Shepard, John B., Yamamoto, Masakazu, Biswas, Arpita A., Stoessel, Sean J., Nicholas, Sarah-Anne E., Cogswell, Cathy A., Devarakonda, Parvathi M., Schneider, Michael J., Cummins, Samantha M., Legendre, Nicholas P., Yamamoto, Shoko, Kaartinen, Vesa, Hunter, Jeffrey W., Goldhamer, David J.
Publicado 2018

Anti-ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1

por Aykul, Senem, Huang, Lily, Wang, Lili, Das, Nanditha M., Reisman, Sandra, Ray, Yonaton, Zhang, Qian, Rothman, Nyanza, Nannuru, Kalyan C., Kamat, Vishal, Brydges, Susannah, Troncone, Luca, Johnsen, Laura, Yu, Paul B., Fazio, Sergio, Lees-Shepard, John, Schutz, Kevin, Murphy, Andrew J., Economides, Aris N., Idone, Vincent, Hatsell, Sarah J.
Publicado 2022

Activin A forms a non-signaling complex with ACVR1 and type II Activin/BMP receptors via its finger 2 tip loop

por Aykul, Senem, Corpina, Richard A, Goebel, Erich J, Cunanan, Camille J, Dimitriou, Alexandra, Kim, Hyon Jong, Zhang, Qian, Rafique, Ashique, Leidich, Raymond, Wang, Xin, McClain, Joyce, Jimenez, Johanna, Nannuru, Kalyan C, Rothman, Nyanza J, Lees-Shepard, John B, Martinez-Hackert, Erik, Murphy, Andrew J, Thompson, Thomas B, Economides, Aris N, Idone, Vincent
Publicado 2020