Cenicriviroc blocks HIV entry but does not lead to redistribution of HIV into extracellular space like maraviroc

por Kramer, Victor, Hassounah, Said, Colby-Germinario, Susan, Mesplède, Thibault, Lefebvre, Eric, Wainberg, Mark
Publicado 2014

Differential impact of the dual CCR2/CCR5 inhibitor cenicriviroc on migration of monocyte and lymphocyte subsets in acute liver injury

por Puengel, Tobias, Krenkel, Oliver, Kohlhepp, Marlene, Lefebvre, Eric, Luedde, Tom, Trautwein, Christian, Tacke, Frank
Publicado 2017

Low Cost and Compact FMCW 24 GHz Radar Applications for Snowpack and Ice Thickness Measurements

por Pomerleau, Patrick, Royer, Alain, Langlois, Alexandre, Cliche, Patrick, Courtemanche, Bruno, Madore, Jean-Benoît, Picard, Ghislain, Lefebvre, Éric
Publicado 2020

Cenicriviroc, a Novel CCR5 (R5) and CCR2 Antagonist, Shows In Vitro Activity against R5 Tropic HIV-2 Clinical Isolates

por Visseaux, Benoit, Charpentier, Charlotte, Collin, Gilles, Bertine, Mélanie, Peytavin, Gilles, Damond, Florence, Matheron, Sophie, Lefebvre, Eric, Brun-Vézinet, Françoise, Descamps, Diane
Publicado 2015

A 48-week randomized phase 2b study evaluating cenicriviroc versus efavirenz in treatment-naive HIV-infected adults with C-C chemokine receptor type 5-tropic virus

por Thompson, Melanie, Saag, Michael, DeJesus, Edwin, Gathe, Joseph, Lalezari, Jay, Landay, Alan L., Cade, Jerry, Enejosa, Jeffrey, Lefebvre, Eric, Feinberg, Judith
Publicado 2016

APOBEC3G/3A Expression in Human Immunodeficiency Virus Type 1-Infected Individuals Following Initiation of Antiretroviral Therapy Containing Cenicriviroc or Efavirenz

por Covino, Daniela A., Purificato, Cristina, Catapano, Laura, Galluzzo, Clementina M., Gauzzi, Maria Cristina, Vella, Stefano, Lefebvre, Eric, Seyedkazemi, Star, Andreotti, Mauro, Fantuzzi, Laura
Publicado 2018

Prolonged cenicriviroc therapy reduces hepatic fibrosis despite steatohepatitis in a diet‐induced mouse model of nonalcoholic steatohepatitis

por Kruger, Annie J., Fuchs, Bryan C., Masia, Ricard, Holmes, Jacinta A., Salloum, Shadi, Sojoodi, Mozhdeh, Ferreira, Diego S., Rutledge, Stephanie M., Caravan, Peter, Alatrakchi, Nadia, Vig, Pam, Lefebvre, Eric, Chung, Raymond T.
Publicado 2018

The Critical Role of Chemokine (C–C Motif) Receptor 2-Positive Monocytes in Autoimmune Cholangitis

por Reuveni, Debby, Gore, Yael, Leung, Patrick S. C., Lichter, Yael, Moshkovits, Itay, Kaminitz, Ayelet, Brazowski, Eli, Lefebvre, Eric, Vig, Pamela, Varol, Chen, Halpern, Zamir, Shibolet, Oren, Gershwin, Merrill Eric, Zigmond, Ehud
Publicado 2018

Antifibrotic Effects of the Dual CCR2/CCR5 Antagonist Cenicriviroc in Animal Models of Liver and Kidney Fibrosis

por Lefebvre, Eric, Moyle, Graeme, Reshef, Ran, Richman, Lee P., Thompson, Melanie, Hong, Feng, Chou, Hsin-l, Hashiguchi, Taishi, Plato, Craig, Poulin, Dominic, Richards, Toni, Yoneyama, Hiroyuki, Jenkins, Helen, Wolfgang, Grushenka, Friedman, Scott L.
Publicado 2016

Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations

por Lowe, Patrick P., Morel, Caroline, Ambade, Aditya, Iracheta-Vellve, Arvin, Kwiatkowski, Erica, Satishchandran, Abhishek, Furi, Istvan, Cho, Yeonhee, Gyongyosi, Benedek, Catalano, Donna, Lefebvre, Eric, Fischer, Laurent, Seyedkazemi, Star, Schafer, Dorothy P., Szabo, Gyongyi
Publicado 2020

Efficacy and Safety of Cenicriviroc in Patients With Primary Sclerosing Cholangitis: PERSEUS Study

por Eksteen, Bertus, Bowlus, Christopher L., Montano‐Loza, Aldo J., Lefebvre, Eric, Fischer, Laurent, Vig, Pamela, Martins, Eduardo Bruno, Ahmad, Jawad, Yimam, Kidist K., Pockros, Paul J., Feld, Jordan J., Minuk, Gerald, Levy, Cynthia
Publicado 2020

A randomized, placebo‐controlled trial of cenicriviroc for treatment of nonalcoholic steatohepatitis with fibrosis

por Friedman, Scott L., Ratziu, Vlad, Harrison, Stephen A., Abdelmalek, Manal F., Aithal, Guruprasad P., Caballeria, Juan, Francque, Sven, Farrell, Geoffrey, Kowdley, Kris V., Craxi, Antonio, Simon, Krzysztof, Fischer, Laurent, Melchor‐Khan, Liza, Vest, Jeffrey, Wiens, Brian L., Vig, Pamela, Seyedkazemi, Star, Goodman, Zachary, Wong, Vincent Wai‐Sun, Loomba, Rohit, Tacke, Frank, Sanyal, Arun, Lefebvre, Eric
Publicado 2018

Dual inhibition of α(v)β(6) and α(v)β(1) reduces fibrogenesis in lung tissue explants from patients with IPF

por Decaris, Martin L., Schaub, Johanna R., Chen, Chun, Cha, Jacob, Lee, Gail G., Rexhepaj, Megi, Ho, Steve S., Rao, Vikram, Marlow, Megan M., Kotak, Prerna, Budi, Erine H., Hooi, Lisa, Wu, Jianfeng, Fridlib, Marina, Martin, Shamra P., Huang, Shaoyi, Chen, Ming, Muñoz, Manuel, Hom, Timothy F., Wolters, Paul J., Desai, Tushar J., Rock, Fernando, Leftheris, Katerina, Morgans, David J., Lepist, Eve-Irene, Andre, Patrick, Lefebvre, Eric A., Turner, Scott M.
Publicado 2021