LCZ696, an angiotensin receptor neprilysin inhibitor (ARNI): clinical development in heart failure and hypertension

por Lefkowitz, Martin P
Publicado 2011

LCZ696 (sacubitril/valsartan), an angiotensin receptor neprilysin inhibitor (ARNI): clinical development in heart failure

por Lefkowitz, Martin P
Publicado 2015

Effects of Sacubitril/Valsartan on Serum Lipids in Heart Failure With Preserved Ejection Fraction

por Selvaraj, Senthil, Claggett, Brian L., Packer, Milton, Zannad, Faiez, Anand, Inder S., Pieske, Burkert, Zhao, Ziqiang, Shi, Victor C., Lefkowitz, Martin P., McMurray, John J. V., Solomon, Scott D.
Publicado 2021

Dual angiotensin receptor and neprilysin inhibition as an alternative to angiotensin-converting enzyme inhibition in patients with chronic systolic heart failure: rationale for and...

por McMurray, John J. V., Packer, Milton, Desai, Akshay S., Gong, Jim, Lefkowitz, Martin P., Rizkala, Adel R., Rouleau, Jean, Shi, Victor C., Solomon, Scott D., Swedberg, Karl, Zile, Michael R.
Publicado 2013

Impact of COVID-19 on Heart Failure Clinical Trials: Insights From the Heart Failure Collaboratory

por Bhatt, Ankeet S., Dimond, Matthew, Fiuzat, Mona, Vaduganathan, Muthiah, Vardeny, Orly, Divanji, Punag, Komtebedde, Jan, Lefkowitz, Martin P., Nkulikiyinka, Richard, Petersson, Magnus, Roessig, Lothar, Schaber, Daniel, O’Connor, Christopher M., Solomon, Scott D.
Publicado 2023

Urinary cGMP (Cyclic Guanosine Monophosphate)/BNP (B-Type Natriuretic Peptide) Ratio, Sacubitril/Valsartan, and Outcomes in Heart Failure With Reduced Ejection Fraction: An Analysi...

por Butt, Jawad H., Ibrahim, Wasyla, Dewan, Pooja, Desai, Akshay S., Køber, Lars, Prescott, Margaret F., Lefkowitz, Martin P., Rouleau, Jean L., Solomon, Scott D., Zile, Michael R., Packer, Milton, Jhund, Pardeep S., McMurray, John J.V.
Publicado 2023

Effects of sacubitril/valsartan versus valsartan on renal function in patients with and without diabetes and heart failure with preserved ejection fraction: insights from PARAGON‐H...

por Peikert, Alexander, Vaduganathan, Muthiah, Mc Causland, Finnian, Claggett, Brian L., Chatur, Safia, Packer, Milton, Pfeffer, Marc A., Zannad, Faiez, Lefkowitz, Martin P., Pieske, Burkert, Düngen, Hans‐Dirk, McMurray, John J.V., Solomon, Scott D.
Publicado 2022

Effect of sacubitril/valsartan vs. enalapril on changes in heart failure therapies over time: the PARADIGM‐HF trial

por Bhatt, Ankeet S., Vaduganathan, Muthiah, Claggett, Brian L., Liu, Jiankang, Packer, Milton, Desai, Akshay S., Lefkowitz, Martin P., Rouleau, Jean L., Shi, Victor C., Zile, Michael R., Swedberg, Karl, Vardeny, Orly, McMurray, John J.V., Solomon, Scott D.
Publicado 2021

Dementia‐related adverse events in PARADIGM‐HF and other trials in heart failure with reduced ejection fraction

por Cannon, Jane A., Shen, Li, Jhund, Pardeep S., Kristensen, Søren L., Køber, Lars, Chen, Fabian, Gong, Jianjian, Lefkowitz, Martin P., Rouleau, Jean L., Shi, Victor C., Swedberg, Karl, Zile, Michael R., Solomon, Scott D., Packer, Milton, McMurray, John J.V.
Publicado 2016

Effect of sacubitril/valsartan on recurrent events in the Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial (PAR...

por Mogensen, Ulrik M., Gong, Jianjian, Jhund, Pardeep S., Shen, Li, Køber, Lars, Desai, Akshay S., Lefkowitz, Martin P., Packer, Milton, Rouleau, Jean L., Solomon, Scott D., Claggett, Brian L., Swedberg, Karl, Zile, Michael R., Mueller‐Velten, Guenther, McMurray, John J.V.
Publicado 2018

Efficacy and safety of LCZ696 (sacubitril-valsartan) according to age: insights from PARADIGM-HF

por Jhund, Pardeep S., Fu, Michael, Bayram, Edmundo, Chen, Chen-Huan, Negrusz-Kawecka, Marta, Rosenthal, Arvo, Desai, Akshay S., Lefkowitz, Martin P., Rizkala, Adel R., Rouleau, Jean L., Shi, Victor C., Solomon, Scott D., Swedberg, Karl, Zile, Michael R., McMurray, John J.V., Packer, Milton
Publicado 2015

Sacubitril/valsartan reduces serum uric acid concentration, an independent predictor of adverse outcomes in PARADIGM‐HF

por Mogensen, Ulrik M., Køber, Lars, Jhund, Pardeep S., Desai, Akshay S., Senni, Michele, Kristensen, Søren L., Dukát, Andrej, Chen, Chen‐Huan, Ramires, Felix, Lefkowitz, Martin P., Prescott, Margaret F., Shi, Victor C., Rouleau, Jean L., Solomon, Scott D., Swedberg, Karl, Packer, Milton, McMurray, John J.V.
Publicado 2017

Effect of sacubitril/valsartan on investigator‐reported ventricular arrhythmias in PARADIGM‐HF

por Curtain, James P., Jackson, Alice M., Shen, Li, Jhund, Pardeep S., Docherty, Kieran F., Petrie, Mark C., Castagno, Davide, Desai, Akshay S., Rohde, Luis E., Lefkowitz, Martin P., Rouleau, Jean‐Lucien, Zile, Michael R., Solomon, Scott D., Swedberg, Karl, Packer, Milton, McMurray, John J.V.
Publicado 2022

Clinical Characteristics and Outcomes of Patients With Heart Failure With Reduced Ejection Fraction and Chronic Obstructive Pulmonary Disease: Insights From PARADIGM‐HF

por Ehteshami‐Afshar, Solmaz, Mooney, Leanne, Dewan, Pooja, Desai, Akshay S., Lang, Ninian N., Lefkowitz, Martin P., Petrie, Mark C., Rizkala, Adel R., Rouleau, Jean L., Solomon, Scott D., Swedberg, Karl, Shi, Victor C., Zile, Michael R., Packer, Milton, McMurray, John J. V., Jhund, Pardeep S., Hawkins, Nathaniel M.
Publicado 2021

Risk Related to Pre–Diabetes Mellitus and Diabetes Mellitus in Heart Failure With Reduced Ejection Fraction: Insights From Prospective Comparison of ARNI With ACEI to Determine Imp...

por Kristensen, Søren L., Preiss, David, Jhund, Pardeep S., Squire, Iain, Cardoso, José Silva, Merkely, Bela, Martinez, Felipe, Starling, Randall C., Desai, Akshay S., Lefkowitz, Martin P., Rizkala, Adel R., Rouleau, Jean L., Shi, Victor C., Solomon, Scott D., Swedberg, Karl, Zile, Michael R., McMurray, John J.V., Packer, Milton
Publicado 2016

Impact of Chronic Obstructive Pulmonary Disease in Patients With Heart Failure With Preserved Ejection Fraction: Insights From PARAGON‐HF

por Mooney, Leanne, Hawkins, Nathaniel M., Jhund, Pardeep S., Redfield, Margaret M., Vaduganathan, Muthiah, Desai, Akshay S., Rouleau, Jean L., Minamisawa, Masatoshi, Shah, Amil M., Lefkowitz, Martin P., Zile, Michael R., Van Veldhuisen, Dirk J., Pfeffer, Marc A., Anand, Inder S., Maggioni, Aldo P., Senni, Michele, Claggett, Brian L., Solomon, Scott D., McMurray, John J. V.
Publicado 2021

Geographic variations in the PARADIGM-HF heart failure trial

por Kristensen, Søren Lund, Martinez, Felipe, Jhund, Pardeep S., Arango, Juan Luis, Bĕlohlávek, Jan, Boytsov, Sergey, Cabrera, Walter, Gomez, Efrain, Hagège, Albert A., Huang, Jun, Kiatchoosakun, Songsak, Kim, Kee-Sik, Mendoza, Iván, Senni, Michele, Squire, Iain B., Vinereanu, Dragos, Wong, Raymond Ching-Chiew, Gong, Jianjian, Lefkowitz, Martin P., Rizkala, Adel R., Rouleau, Jean L., Shi, Victor C., Solomon, Scott D., Swedberg, Karl, Zile, Michael R., Packer, Milton, McMurray, John J.V.
Publicado 2016

Diabetes and pre‐diabetes in patients with heart failure and preserved ejection fraction

por Jackson, Alice M., Rørth, Rasmus, Liu, Jiankang, Kristensen, Søren Lund, Anand, Inder S., Claggett, Brian L., Cleland, John G.F., Chopra, Vijay K., Desai, Akshay S., Ge, Junbo, Gong, Jianjian, Lam, Carolyn S.P., Lefkowitz, Martin P., Maggioni, Aldo P., Martinez, Felipe, Packer, Milton, Pfeffer, Marc A., Pieske, Burkert, Redfield, Margaret M., Rizkala, Adel R., Rouleau, Jean L., Seferović, Petar M., Tromp, Jasper, Van Veldhuisen, Dirk J., Yilmaz, Mehmet B., Zannad, Faiez, Zile, Michael R., Køber, Lars, Petrie, Mark C., Jhund, Pardeep S., Solomon, Scott D., McMurray, John J.V.
Publicado 2022