Calcineurin A beta deficiency ameliorates HFD-induced hypothalamic astrocytosis in mice

por Pfuhlmann, Katrin, Schriever, Sonja C., Legutko, Beata, Baumann, Peter, Harrison, Luke, Kabra, Dhiraj G., Baumgart, Emily Violette, Tschöp, Matthias H., Garcia-Caceres, Cristina, Pfluger, Paul T.
Publicado 2018

Dual melanocortin-4 receptor and GLP-1 receptor agonism amplifies metabolic benefits in diet-induced obese mice

por Clemmensen, Christoffer, Finan, Brian, Fischer, Katrin, Tom, Robby Zachariah, Legutko, Beata, Sehrer, Laura, Heine, Daniela, Grassl, Niklas, Meyer, Carola W, Henderson, Bart, Hofmann, Susanna M, Tschöp, Matthias H, Van der Ploeg, Lex HT, Müller, Timo D
Publicado 2015

TNFα drives mitochondrial stress in POMC neurons in obesity

por Yi, Chun-Xia, Walter, Marc, Gao, Yuanqing, Pitra, Soledad, Legutko, Beata, Kälin, Stefanie, Layritz, Clarita, García-Cáceres, Cristina, Bielohuby, Maximilian, Bidlingmaier, Martin, Woods, Stephen C., Ghanem, Alexander, Conzelmann, Karl-Klaus, Stern, Javier E., Jastroch, Martin, Tschöp, Matthias H.
Publicado 2017

Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1

por González-García, Ismael, García-Clavé, Elena, Cebrian-Serrano, Alberto, Le Thuc, Ophélia, Contreras, Raian E., Xu, Yanjun, Gruber, Tim, Schriever, Sonja C., Legutko, Beata, Lintelmann, Jutta, Adamski, Jerzy, Wurst, Wolfgang, Müller, Timo D., Woods, Stephen C., Pfluger, Paul T., Tschöp, Matthias H., Fisette, Alexandre, García-Cáceres, Cristina
Publicado 2023

Dietary sugars, not lipids, drive hypothalamic inflammation

por Gao, Yuanqing, Bielohuby, Maximilian, Fleming, Thomas, Grabner, Gernot F., Foppen, Ewout, Bernhard, Wagner, Guzmán-Ruiz, Mara, Layritz, Clarita, Legutko, Beata, Zinser, Erwin, García-Cáceres, Cristina, Buijs, Ruud M., Woods, Stephen C., Kalsbeek, Andries, Seeley, Randy J., Nawroth, Peter P., Bidlingmaier, Martin, Tschöp, Matthias H., Yi, Chun-Xia
Publicado 2017

Chronic d-serine supplementation impairs insulin secretion

por Suwandhi, Lisa, Hausmann, Simone, Braun, Alexander, Gruber, Tim, Heinzmann, Silke S., Gálvez, Eric J.C., Buck, Achim, Legutko, Beata, Israel, Andreas, Feuchtinger, Annette, Haythorne, Elizabeth, Staiger, Harald, Heni, Martin, Häring, Hans-Ulrich, Schmitt-Kopplin, Philippe, Walch, Axel, Cáceres, Cristina García, Tschöp, Matthias H., Rutter, Guy A., Strowig, Till, Elsner, Martin, Ussar, Siegfried
Publicado 2018

Hypothalamic leptin action is mediated by histone deacetylase 5

por Kabra, Dhiraj G., Pfuhlmann, Katrin, García-Cáceres, Cristina, Schriever, Sonja C., Casquero García, Veronica, Kebede, Adam Fiseha, Fuente-Martin, Esther, Trivedi, Chitrang, Heppner, Kristy, Uhlenhaut, N. Henriette, Legutko, Beata, Kabra, Uma D., Gao, Yuanqing, Yi, Chun-Xia, Quarta, Carmelo, Clemmensen, Christoffer, Finan, Brian, Müller, Timo D., Meyer, Carola W., Paez-Pereda, Marcelo, Stemmer, Kerstin, Woods, Stephen C., Perez-Tilve, Diego, Schneider, Robert, Olson, Eric N., Tschöp, Matthias H., Pfluger, Paul T.
Publicado 2016

Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension

por Gruber, Tim, Pan, Chenchen, Contreras, Raian E., Wiedemann, Tobias, Morgan, Donald A., Skowronski, Alicja A., Lefort, Sandrine, De Bernardis Murat, Cahuê, Le Thuc, Ophelia, Legutko, Beata, Ruiz-Ojeda, Francisco J., Fuente-Fernández, María de la, García-Villalón, Angel Luis, González-Hedström, Daniel, Huber, Melanie, Szigeti-Buck, Klara, Müller, Timo D., Ussar, Siegfried, Pfluger, Paul, Woods, Steve C., Ertürk, Ali, LeDuc, Charles A., Rahmouni, Kamal, Granado, Miriam, Horvath, Tamas L., Tschöp, Matthias H., García-Cáceres, Cristina
Publicado 2021

The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling

por Zhang, Qian, Delessa, Challa Tenagne, Augustin, Robert, Bakhti, Mostafa, Colldén, Gustav, Drucker, Daniel J., Feuchtinger, Annette, Caceres, Cristina Garcia, Grandl, Gerald, Harger, Alexandra, Herzig, Stephan, Hofmann, Susanna, Holleman, Cassie Lynn, Jastroch, Martin, Keipert, Susanne, Kleinert, Maximilian, Knerr, Patrick J., Kulaj, Konxhe, Legutko, Beata, Lickert, Heiko, Liu, Xue, Luippold, Gerd, Lutter, Dominik, Malogajski, Emilija, Medina, Marta Tarquis, Mowery, Stephanie A., Blutke, Andreas, Perez-Tilve, Diego, Salinno, Ciro, Sehrer, Laura, DiMarchi, Richard D., Tschöp, Matthias H., Stemmer, Kerstin, Finan, Brian, Wolfrum, Christian, Müller, Timo D.
Publicado 2021