Naturally-aged microglia exhibit phagocytic dysfunction accompanied by gene expression changes reflective of underlying neurologic disease

por Thomas, Alyssa L., Lehn, Maria A., Janssen, Edith M., Hildeman, David A., Chougnet, Claire A.
Publicado 2022

CD244 represents a new therapeutic target in head and neck squamous cell carcinoma

por Agresta, Laura, Lehn, Maria, Lampe, Kristin, Cantrell, Rachel, Hennies, Cassandra, Szabo, Sara, Wise-Draper, Trisha, Conforti, Laura, Hoebe, Kasper, Janssen, Edith M
Publicado 2020

DNA methylation dynamics during ex vivo differentiation and maturation of human dendritic cells

por Zhang, Xue, Ulm, Ashley, Somineni, Hari K, Oh, Sunghee, Weirauch, Matthew T, Zhang, Hong-Xuan, Chen, Xiaoting, Lehn, Maria A, Janssen, Edith M, Ji, Hong
Publicado 2014

Promotion of Anti-Tuberculosis Macrophage Activity by L-Arginine in the Absence of Nitric Oxide

por McKell, Melanie C., Crowther, Rebecca R., Schmidt, Stephanie M., Robillard, Michelle C., Cantrell, Rachel, Lehn, Maria A., Janssen, Edith M., Qualls, Joseph E.
Publicado 2021

PD1 blockade enhances K(+) channel activity, Ca(2+) signaling, and migratory ability in cytotoxic T lymphocytes of patients with head and neck cancer

por Newton, Hannah S, Gawali, Vaibhavkumar S, Chimote, Ameet A, Lehn, Maria A, Palackdharry, Sarah M, Hinrichs, Benjamin H, Jandarov, Roman, Hildeman, David, Janssen, Edith M, Wise-Draper, Trisha M, Conforti, Laura
Publicado 2020

Metformin increases natural killer cell functions in head and neck squamous cell carcinoma through CXCL1 inhibition

por Crist, McKenzie, Yaniv, Benyamin, Palackdharry, Sarah, Lehn, Maria A, Medvedovic, Mario, Stone, Timothy, Gulati, Shuchi, Karivedu, Vidhya, Borchers, Michael, Fuhrman, Bethany, Crago, Audrey, Curry, Joseph, Martinez-Outschoorn, Ubaldo, Takiar, Vinita, Wise-Draper, Trisha M
Publicado 2022

Single cell transcriptomic analysis of HPV16-infected epithelium identifies a keratinocyte subpopulation implicated in cancer

por Bedard, Mary C., Chihanga, Tafadzwa, Carlile, Adrean, Jackson, Robert, Brusadelli, Marion G., Lee, Denis, VonHandorf, Andrew, Rochman, Mark, Dexheimer, Phillip J., Chalmers, Jeffrey, Nuovo, Gerard, Lehn, Maria, Williams, David E. J., Kulkarni, Aditi, Carey, Molly, Jackson, Amanda, Billingsley, Caroline, Tang, Alice, Zender, Chad, Patil, Yash, Wise-Draper, Trisha M., Herzog, Thomas J., Ferris, Robert L., Kendler, Ady, Aronow, Bruce J., Kofron, Matthew, Rothenberg, Marc E., Weirauch, Matthew T., Van Doorslaer, Koenraad, Wikenheiser-Brokamp, Kathryn A., Lambert, Paul F., Adam, Mike, Steven Potter, S., Wells, Susanne I.
Publicado 2023