Translation attenuation by PERK balances ER glycoprotein synthesis with lipid-linked oligosaccharide flux

por Shang, Jie, Gao, Ningguo, Kaufman, Randal J., Ron, David, Harding, Heather P., Lehrman, Mark A.
Publicado 2007

Signal recognition particle receptor-β (SR-β) coordinates cotranslational N-glycosylation

por Phoomak, Chatchai, Rinis, Natalie, Baro, Marta, Shrimal, Shiteshu, Bennett, Daniel, Shaffer, Scott A., Lehrman, Mark, Gilmore, Reid, Contessa, Joseph N.
Publicado 2023

A zebrafish model of congenital disorders of glycosylation with phosphomannose isomerase deficiency reveals an early opportunity for corrective mannose supplementation

por Chu, Jaime, Mir, Alexander, Gao, Ningguo, Rosa, Sabrina, Monson, Christopher, Sharma, Vandana, Steet, Richard, Freeze, Hudson H., Lehrman, Mark A., Sadler, Kirsten C.
Publicado 2013

Glycoprotein Biosynthesis in a Eukaryote Lacking the Membrane Protein Rft1

por Jelk, Jennifer, Gao, Ningguo, Serricchio, Mauro, Signorell, Aita, Schmidt, Remo S., Bangs, James D., Acosta-Serrano, Alvaro, Lehrman, Mark A., Bütikofer, Peter, Menon, Anant K.
Publicado 2013

A bioactive mammalian disaccharide associated with autoimmunity activates STING-TBK1-dependent immune response

por Fermaintt, Charles S., Sano, Kanae, Liu, Zhida, Ishii, Nozomi, Seino, Junichi, Dobbs, Nicole, Suzuki, Tadashi, Fu, Yang-Xin, Lehrman, Mark A., Matsuo, Ichiro, Yan, Nan
Publicado 2019

Antiangiogenic Activity of 2-Deoxy-D-Glucose

por Merchan, Jaime R., Kovács, Krisztina, Railsback, Jaclyn W., Kurtoglu, Metin, Jing, Yuqi, Piña, Yolanda, Gao, Ningguo, Murray, Timothy G., Lehrman, Mark A., Lampidis, Theodore J.
Publicado 2010

A zebrafish model of PMM2-CDG reveals altered neurogenesis and a substrate-accumulation mechanism for N-linked glycosylation deficiency

por Cline, Abigail, Gao, Ningguo, Flanagan-Steet, Heather, Sharma, Vandana, Rosa, Sabrina, Sonon, Roberto, Azadi, Parastoo, Sadler, Kirsten C., Freeze, Hudson H., Lehrman, Mark A., Steet, Richard
Publicado 2012

Mannose-6-phosphate regulates destruction of lipid-linked oligosaccharides

por Gao, Ningguo, Shang, Jie, Huynh, Dang, Manthati, Vijaya L., Arias, Carolina, Harding, Heather P., Kaufman, Randal J., Mohr, Ian, Ron, David, Falck, John R., Lehrman, Mark A.
Publicado 2011

Protease-dependent defects in N-cadherin processing drive PMM2-CDG pathogenesis

por Klaver, Elsenoor J., Dukes-Rimsky, Lynn, Kumar, Brijesh, Xia, Zhi-Jie, Dang, Tammie, Lehrman, Mark A., Angel, Peggi, Drake, Richard R., Freeze, Hudson H., Steet, Richard, Flanagan-Steet, Heather
Publicado 2021

trappc11 is required for protein glycosylation in zebrafish and humans

por DeRossi, Charles, Vacaru, Ana, Rafiq, Ruhina, Cinaroglu, Ayca, Imrie, Dru, Nayar, Shikha, Baryshnikova, Anastasia, Milev, Miroslav P., Stanga, Daniela, Kadakia, Dhara, Gao, Ningguo, Chu, Jaime, Freeze, Hudson H., Lehrman, Mark A., Sacher, Michael, Sadler, Kirsten C.
Publicado 2016

De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma

por Shi, Diana D., Savani, Milan R., Levitt, Michael M., Wang, Adam C., Endress, Jennifer E., Bird, Cylaina E., Buehler, Joseph, Stopka, Sylwia A., Regan, Michael S., Lin, Yu-Fen, Puliyappadamba, Vinesh T., Gao, Wenhua, Khanal, Januka, Evans, Laura, Lee, Joyce H., Guo, Lei, Xiao, Yi, Xu, Min, Huang, Bofu, Jennings, Rebecca B., Bonal, Dennis M., Martin-Sandoval, Misty S., Dang, Tammie, Gattie, Lauren C., Cameron, Amy B., Lee, Sungwoo, Asara, John M., Kornblum, Harley I., Mak, Tak W., Looper, Ryan E., Nguyen, Quang-De, Signoretti, Sabina, Gradl, Stefan, Sutter, Andreas, Jeffers, Michael, Janzer, Andreas, Lehrman, Mark A., Zacharias, Lauren G., Mathews, Thomas P., Losman, Julie-Aurore, Richardson, Timothy E., Cahill, Daniel P., DeBerardinis, Ralph J., Ligon, Keith L., Xu, Lin, Ly, Peter, Agar, Nathalie Y.R., Abdullah, Kalil G., Harris, Isaac S., Kaelin, William G., McBrayer, Samuel K.
Publicado 2022