Development of TRPM8 Antagonists to Treat Chronic Pain and Migraine

por Weyer, Andy D., Lehto, Sonya G.
Publicado 2017

Transient receptor potential melastatin 8 (TRPM8) channels are involved in body temperature regulation

por Gavva, Narender R, Davis, Carl, Lehto, Sonya G, Rao, Sara, Wang, Weiya, Zhu, Dawn XD
Publicado 2012

Functional similarity of ABP 959 and eculizumab in simulated serum models of aHUS and NMOSD

por McBride, Helen J., Frazer-Abel, Ashley, Thiemann, Sandra, Lehto, Sonya G., Hutterer, Katariina M., Liu, Jennifer
Publicado 2023

AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodynia

por Lehto, Sonya G., Weyer, Andy D., Zhang, Maosheng, Youngblood, Beth D., Wang, Judy, Wang, Weiya, Kerstein, Patrick C., Davis, Carl, Wild, Kenneth D., Stucky, Cheryl L., Gavva, Narender R.
Publicado 2015

PAC(1) receptor blockade reduces central nociceptive activity: new approach for primary headache?

por Hoffmann, Jan, Miller, Silke, Martins-Oliveira, Margarida, Akerman, Simon, Supronsinchai, Weera, Sun, Hong, Shi, Licheng, Wang, Judy, Zhu, Dawn, Lehto, Sonya, Liu, Hantao, Yin, Ruoyuan, Moyer, Bryan D., Xu, Cen, Goadsby, Peter J.
Publicado 2020

Selective antagonism of TRPA1 produces limited efficacy in models of inflammatory- and neuropathic-induced mechanical hypersensitivity in rats

por Lehto, Sonya G, Weyer, Andy D, Youngblood, Beth D, Zhang, Maosheng, Yin, Ruoyuan, Wang, Weiya, Teffera, Yohannes, Cooke, Melanie, Stucky, Cheryl L, Schenkel, Laurie, Geuns-Meyer, Stephanie, Moyer, Bryan D, Wild, Kenneth D, Gavva, Narender R
Publicado 2016