L-Type Amino Acid Transporter 1-Utilizing Prodrugs of Ketoprofen Can Efficiently Reduce Brain Prostaglandin Levels

por Montaser, Ahmed, Lehtonen, Marko, Gynther, Mikko, Huttunen, Kristiina M.
Publicado 2020

Non-targeted metabolite profiling reveals changes in oxidative stress, tryptophan and lipid metabolisms in fearful dogs

por Puurunen, Jenni, Tiira, Katriina, Lehtonen, Marko, Hanhineva, Kati, Lohi, Hannes
Publicado 2016

Lipid phosphate phosphatase inhibitors locally amplify lysophosphatidic acid LPA(1) receptor signalling in rat brain cryosections without affecting global LPA degradation

por Aaltonen, Niina, Lehtonen, Marko, Varonen, Katri, Goterris, Gemma Arrufat, Laitinen, Jarmo T
Publicado 2012

Serum metabolites associated with wholegrain consumption using nontargeted metabolic profiling: a discovery and reproducibility study

por Noerman, Stefania, Virtanen, Jyrki K., Lehtonen, Marko, Brunius, Carl, Hanhineva, Kati
Publicado 2022

Fearful dogs have increased plasma glutamine and γ-glutamyl glutamine

por Puurunen, Jenni, Tiira, Katriina, Vapalahti, Katariina, Lehtonen, Marko, Hanhineva, Kati, Lohi, Hannes
Publicado 2018

Caenorhabditis Elegans Mutants Predict Regulation of Fatty Acids and Endocannabinoids by the CYP-35A Gene Family

por Aarnio, Vuokko, Lehtonen, Marko, Storvik, Markus, Callaway, James C., Lakso, Merja, Wong, Garry
Publicado 2011

In Vitro Human Metabolism and Inhibition Potency of Verbascoside for CYP Enzymes

por Reid, Anna-Mari, Juvonen, Risto, Huuskonen, Pasi, Lehtonen, Marko, Pasanen, Markku, Lall, Namrita
Publicado 2019

Aerobic exercise training and gut microbiome-associated metabolic shifts in women with overweight: a multi-omic study

por Hintikka, Jukka E., Ahtiainen, Juha P., Permi, Perttu, Jalkanen, Sirpa, Lehtonen, Marko, Pekkala, Satu
Publicado 2023

A non-targeted metabolite profiling pilot study suggests that tryptophan and lipid metabolisms are linked with ADHD-like behaviours in dogs

por Puurunen, Jenni, Sulkama, Sini, Tiira, Katriina, Araujo, Cesar, Lehtonen, Marko, Hanhineva, Kati, Lohi, Hannes
Publicado 2016

Buprenorphine plasma and cerebrospinal fluid concentrations in osteoarthritis patients during low-dose transdermal patch dosing

por Härkänen, Lasse, Hakomäki, Henriikka, Huopio, Jukka, Kokki, Hannu, Korhonen, Sanni, Lehtonen, Marko, Sjövall, Sari, Kokki, Merja
Publicado 2023

A prospective, randomized, open label, controlled study investigating the efficiency and safety of 3 different methods of rectus sheath block analgesia following midline laparotomy

por Purdy, Martin, Kinnunen, Mari, Kokki, Merja, Anttila, Maarit, Eskelinen, Matti, Hautajärvi, Heidi, Lehtonen, Marko, Kokki, Hannu
Publicado 2018

Pharmacokinetics of buprenorphine in pregnant sheep after intravenous injection

por Hakomäki, Henriikka, Kokki, Hannu, Lehtonen, Marko, Ranta, Veli‐Pekka, Räsänen, Juha, Voipio, Hanna‐Marja, Kokki, Merja
Publicado 2021

Plasma metabolites associated with type 2 diabetes in a Swedish population: a case–control study nested in a prospective cohort

por Shi, Lin, Brunius, Carl, Lehtonen, Marko, Auriola, Seppo, Bergdahl, Ingvar A., Rolandsson, Olov, Hanhineva, Kati, Landberg, Rikard
Publicado 2018

Ganciclovir and Its Hemocompatible More Lipophilic Derivative Can Enhance the Apoptotic Effects of Methotrexate by Inhibiting Breast Cancer Resistance Protein (BCRP)

por Markowicz-Piasecka, Magdalena, Huttunen, Johanna, Montaser, Ahmed, Adla, Santosh Kumar, Auriola, Seppo, Lehtonen, Marko, Huttunen, Kristiina M.
Publicado 2021

A Non-Targeted LC-MS Profiling Reveals Elevated Levels of Carnitine Precursors and Trimethylated Compounds in the Cord Plasma of Pre-Eclamptic Infants

por Jääskeläinen, Tiina, Kärkkäinen, Olli, Jokkala, Jenna, Litonius, Kaisa, Heinonen, Seppo, Auriola, Seppo, Lehtonen, Marko, Hanhineva, Kati, Laivuori, Hannele
Publicado 2018

A non-targeted LC–MS metabolic profiling of pregnancy: longitudinal evidence from healthy and pre-eclamptic pregnancies

por Jääskeläinen, Tiina, Kärkkäinen, Olli, Jokkala, Jenna, Klåvus, Anton, Heinonen, Seppo, Auriola, Seppo, Lehtonen, Marko, Hanhineva, Kati, Laivuori, Hannele
Publicado 2021

Tissue-wide metabolomics reveals wide impact of gut microbiota on mice metabolite composition

por Zarei, Iman, Koistinen, Ville M., Kokla, Marietta, Klåvus, Anton, Babu, Ambrin Farizah, Lehtonen, Marko, Auriola, Seppo, Hanhineva, Kati
Publicado 2022

Pregnane X receptor activation remodels glucose metabolism to promote NAFLD development in obese mice

por Karpale, Mikko, Kummu, Outi, Kärkkäinen, Olli, Lehtonen, Marko, Näpänkangas, Juha, Herfurth, Uta M., Braeuning, Albert, Rysä, Jaana, Hakkola, Jukka
Publicado 2023

CMPF Does Not Associate with Impaired Glucose Metabolism in Individuals with Features of Metabolic Syndrome

por Lankinen, Maria A., Hanhineva, Kati, Kolehmainen, Marjukka, Lehtonen, Marko, Auriola, Seppo, Mykkänen, Hannu, Poutanen, Kaisa, Schwab, Ursula, Uusitupa, Matti
Publicado 2015

Metabolite Pattern Derived from Lactiplantibacillus plantarum—Fermented Rye Foods and In Vitro Gut Fermentation Synergistically Inhibits Bacterial Growth

por Koistinen, Ville M., Hedberg, Maria, Shi, Lin, Johansson, Anders, Savolainen, Otto, Lehtonen, Marko, Aura, Anna‐Marja, Hanhineva, Kati, Landberg, Rikard
Publicado 2022