Identification of sample-specific regulations using integrative network level analysis

por Liu, Chengyu, Louhimo, Riku, Laakso, Marko, Lehtonen, Rainer, Hautaniemi, Sampsa
Publicado 2015

Genetic effects on life-history traits in the Glanville fritillary butterfly

por Duplouy, Anne, Wong, Swee C., Corander, Jukka, Lehtonen, Rainer, Hanski, Ilkka
Publicado 2017

SePIA: RNA and small RNA sequence processing, integration, and analysis

por Icay, Katherine, Chen, Ping, Cervera, Alejandra, Rantanen, Ville, Lehtonen, Rainer, Hautaniemi, Sampsa
Publicado 2016

Data integration to prioritize drugs using genomics and curated data

por Louhimo, Riku, Laakso, Marko, Belitskin, Denis, Klefström, Juha, Lehtonen, Rainer, Hautaniemi, Sampsa
Publicado 2016

Rule-based induction method for haplotype comparison and identification of candidate disease loci

por Karinen, Sirkku, Saarinen, Silva, Lehtonen, Rainer, Rastas, Pasi, Vahteristo, Pia, Aaltonen, Lauri A, Hautaniemi, Sampsa
Publicado 2012

Effects of ambient and preceding temperatures and metabolic genes on flight metabolism in the Glanville fritillary butterfly

por Wong, Swee Chong, Oksanen, Alma, Mattila, Anniina L.K., Lehtonen, Rainer, Niitepõld, Kristjan, Hanski, Ilkka
Publicado 2016

Multiple components of PKA and TGF-β pathways are mutated in pseudomyxoma peritonei

por Saarinen, Lilli, Nummela, Pirjo, Thiel, Alexandra, Lehtonen, Rainer, Järvinen, Petrus, Järvinen, Heikki, Aaltonen, Lauri A., Lepistö, Anna, Hautaniemi, Sampsa, Ristimäki, Ari
Publicado 2017

SNP Design from 454 Sequencing of Podosphaera plantaginis Transcriptome Reveals a Genetically Diverse Pathogen Metapopulation with High Levels of Mixed-Genotype Infection

por Tollenaere, Charlotte, Susi, Hanna, Nokso-Koivisto, Jussi, Koskinen, Patrik, Tack, Ayco, Auvinen, Petri, Paulin, Lars, Frilander, Mikko J., Lehtonen, Rainer, Laine, Anna-Liisa
Publicado 2012

Drug screening approach combines epigenetic sensitization with immunochemotherapy in cancer

por Facciotto, Chiara, Casado, Julia, Turunen, Laura, Leivonen, Suvi-Katri, Tumiati, Manuela, Rantanen, Ville, Kauppi, Liisa, Lehtonen, Rainer, Leppä, Sirpa, Wennerberg, Krister, Hautaniemi, Sampsa
Publicado 2019

Complete androgen insensitivity syndrome caused by a deep intronic pseudoexon-activating mutation in the androgen receptor gene

por Känsäkoski, Johanna, Jääskeläinen, Jarmo, Jääskeläinen, Tiina, Tommiska, Johanna, Saarinen, Lilli, Lehtonen, Rainer, Hautaniemi, Sampsa, Frilander, Mikko J., Palvimo, Jorma J., Toppari, Jorma, Raivio, Taneli
Publicado 2016

qSNE: quadratic rate t-SNE optimizer with automatic parameter tuning for large datasets

por Häkkinen, Antti, Koiranen, Juha, Casado, Julia, Kaipio, Katja, Lehtonen, Oskari, Petrucci, Eleonora, Hynninen, Johanna, Hietanen, Sakari, Carpén, Olli, Pasquini, Luca, Biffoni, Mauro, Lehtonen, Rainer, Hautaniemi, Sampsa
Publicado 2020

FUNGI: FUsioN Gene Integration toolset

por Cervera, Alejandra, Rausio, Heidi, Kähkönen, Tiia, Andersson, Noora, Partel, Gabriele, Rantanen, Ville, Paciello, Giulia, Ficarra, Elisa, Hynninen, Johanna, Hietanen, Sakari, Carpén, Olli, Lehtonen, Rainer, Hautaniemi, Sampsa, Huhtinen, Kaisa
Publicado 2021

EPHB2 germline variants in patients with colorectal cancer or hyperplastic polyposis

por Kokko, Antti, Laiho, Päivi, Lehtonen, Rainer, Korja, Sanna, Carvajal-Carmona, Luis G, Järvinen, Heikki, Mecklin, Jukka-Pekka, Eng, Charis, Schleutker, Johanna, Tomlinson, Ian PM, Vahteristo, Pia, Aaltonen, Lauri A
Publicado 2006

Nationwide Registry-Based Analysis of Cancer Clustering Detects Strong Familial Occurrence of Kaposi Sarcoma

por Kaasinen, Eevi, Aavikko, Mervi, Vahteristo, Pia, Patama, Toni, Li, Yilong, Saarinen, Silva, Kilpivaara, Outi, Pitkänen, Esa, Knekt, Paul, Laaksonen, Maarit, Artama, Miia, Lehtonen, Rainer, Aaltonen, Lauri A., Pukkala, Eero
Publicado 2013

Prospective Longitudinal ctDNA Workflow Reveals Clinically Actionable Alterations in Ovarian Cancer

por Oikkonen, Jaana, Zhang, Kaiyang, Salminen, Liina, Schulman, Ingrid, Lavikka, Kari, Andersson, Noora, Ojanperä, Erika, Hietanen, Sakari, Grénman, Seija, Lehtonen, Rainer, Huhtinen, Kaisa, Carpén, Olli, Hynninen, Johanna, Färkkilä, Anniina, Hautaniemi, Sampsa
Publicado 2019

PRISM: recovering cell-type-specific expression profiles from individual composite RNA-seq samples

por Häkkinen, Antti, Zhang, Kaiyang, Alkodsi, Amjad, Andersson, Noora, Erkan, Erdogan Pekcan, Dai, Jun, Kaipio, Katja, Lamminen, Tarja, Mansuri, Naziha, Huhtinen, Kaisa, Vähärautio, Anna, Carpén, Olli, Hynninen, Johanna, Hietanen, Sakari, Lehtonen, Rainer, Hautaniemi, Sampsa
Publicado 2021

MicroRNAs regulate key cell survival pathways and mediate chemosensitivity during progression of diffuse large B-cell lymphoma

por Leivonen, Suvi-Katri, Icay, Katherine, Jäntti, Kirsi, Siren, Ilari, Liu, Chengyu, Alkodsi, Amjad, Cervera, Alejandra, Ludvigsen, Maja, Hamilton-Dutoit, Stephen Jacques, d’Amore, Francesco, Karjalainen-Lindsberg, Marja-Liisa, Delabie, Jan, Holte, Harald, Lehtonen, Rainer, Hautaniemi, Sampsa, Leppä, Sirpa
Publicado 2017

Genetic predisposition to uterine leiomyoma is determined by loci for genitourinary development and genome stability

por Välimäki, Niko, Kuisma, Heli, Pasanen, Annukka, Heikinheimo, Oskari, Sjöberg, Jari, Bützow, Ralf, Sarvilinna, Nanna, Heinonen, Hanna-Riikka, Tolvanen, Jaana, Bramante, Simona, Tanskanen, Tomas, Auvinen, Juha, Uimari, Outi, Alkodsi, Amjad, Lehtonen, Rainer, Kaasinen, Eevi, Palin, Kimmo, Aaltonen, Lauri A
Publicado 2018

Co-evolution of matrisome and adaptive adhesion dynamics drives ovarian cancer chemoresistance

por Pietilä, Elina A., Gonzalez-Molina, Jordi, Moyano-Galceran, Lidia, Jamalzadeh, Sanaz, Zhang, Kaiyang, Lehtinen, Laura, Turunen, S. Pauliina, Martins, Tomás A., Gultekin, Okan, Lamminen, Tarja, Kaipio, Katja, Joneborg, Ulrika, Hynninen, Johanna, Hietanen, Sakari, Grénman, Seija, Lehtonen, Rainer, Hautaniemi, Sampsa, Carpén, Olli, Carlson, Joseph W., Lehti, Kaisa
Publicado 2021

Impact of constitutional TET2 haploinsufficiency on molecular and clinical phenotype in humans

por Kaasinen, Eevi, Kuismin, Outi, Rajamäki, Kristiina, Ristolainen, Heikki, Aavikko, Mervi, Kondelin, Johanna, Saarinen, Silva, Berta, Davide G., Katainen, Riku, Hirvonen, Elina A. M., Karhu, Auli, Taira, Aurora, Tanskanen, Tomas, Alkodsi, Amjad, Taipale, Minna, Morgunova, Ekaterina, Franssila, Kaarle, Lehtonen, Rainer, Mäkinen, Markus, Aittomäki, Kristiina, Palotie, Aarno, Kurki, Mitja I., Pietiläinen, Olli, Hilpert, Morgane, Saarentaus, Elmo, Niinimäki, Jaakko, Junttila, Juhani, Kaikkonen, Kari, Vahteristo, Pia, Skoda, Radek C., Seppänen, Mikko R. J., Eklund, Kari K., Taipale, Jussi, Kilpivaara, Outi, Aaltonen, Lauri A.
Publicado 2019