Giving the Genes a Shuffle: Using Natural Variation to Understand Host Genetic Contributions to Viral Infections

por Leist, Sarah R., Baric, Ralph S.
Publicado 2018

Genetically Engineering a Susceptible Mouse Model for MERS-CoV-Induced Acute Respiratory Distress Syndrome

por Leist, Sarah R., Cockrell, Adam S.
Publicado 2019

Cell and animal models of SARS-CoV-2 pathogenesis and immunity

por Leist, Sarah R., Schäfer, Alexandra, Martinez, David R.
Publicado 2020

Modeling pathogenesis of emergent and pre-emergent human coronaviruses in mice

por Cockrell, Adam S., Leist, Sarah R., Douglas, Madeline G., Baric, Ralph S.
Publicado 2018

Increasing the translation of mouse models of MERS coronavirus pathogenesis through kinetic hematological analysis

por Leist, Sarah R., Jensen, Kara L., Baric, Ralph S., Sheahan, Timothy P.
Publicado 2019

Lst1 deficiency has a minor impact on course and outcome of the host response to influenza A H1N1 infections in mice

por Leist, Sarah R., Kollmus, Heike, Hatesuer, Bastian, Lambertz, Ruth L. O., Schughart, Klaus
Publicado 2016

Of mice and men: the host response to influenza virus infection

por Kollmus, Heike, Pilzner, Carolin, Leist, Sarah R., Heise, Mark, Geffers, Robert, Schughart, Klaus
Publicado 2018

27th International Mammalian Genome Conference meeting report

por Gamache, Benjamin, Leist, Sarah R., Bard, Andrew Daniel, Logan, Darren W., Carpanini, Sarah M.
Publicado 2014

RNAseq expression analysis of resistant and susceptible mice after influenza A virus infection identifies novel genes associated with virus replication and important for host resis...

por Wilk, Esther, Pandey, Ashutosh K., Leist, Sarah Rebecca, Hatesuer, Bastian, Preusse, Matthias, Pommerenke, Claudia, Wang, Junxi, Schughart, Klaus
Publicado 2015

H2 influenza A virus is not pathogenic in Tmprss2 knock-out mice

por Lambertz, Ruth Lydia Olga, Gerhauser, Ingo, Nehlmeier, Inga, Gärtner, Sabine, Winkler, Michael, Leist, Sarah Rebecca, Kollmus, Heike, Pöhlmann, Stefan, Schughart, Klaus
Publicado 2020

Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice

por Leist, Sarah R., Pilzner, Carolin, van den Brand, Judith M.A., Dengler, Leonie, Geffers, Robert, Kuiken, Thijs, Balling, Rudi, Kollmus, Heike, Schughart, Klaus
Publicado 2016

Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis

por Gralinski, Lisa E., Sheahan, Timothy P., Morrison, Thomas E., Menachery, Vineet D., Jensen, Kara, Leist, Sarah R., Whitmore, Alan, Heise, Mark T., Baric, Ralph S.
Publicado 2018

In vivo knockdown of Piccolino disrupts presynaptic ribbon morphology in mouse photoreceptor synapses

por Regus-Leidig, Hanna, Fuchs, Michaela, Löhner, Martina, Leist, Sarah R., Leal-Ortiz, Sergio, Chiodo, Vince A., Hauswirth, William W., Garner, Craig C., Brandstätter, Johann H.
Publicado 2014

Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as a live virus vaccine candidate

por Sun, Weina, Leist, Sarah R., McCroskery, Stephen, Liu, Yonghong, Slamanig, Stefan, Oliva, Justine, Amanat, Fatima, Schäfer, Alexandra, Dinnon, Kenneth H., García-Sastre, Adolfo, Krammer, Florian, Baric, Ralph S., Palese, Peter
Publicado 2020

Mouse Adapted SARS-CoV-2 (MA10) Viral Infection Induces Neuroinflammation in Standard Laboratory Mice

por Amruta, Narayanappa, Ismael, Saifudeen, Leist, Sarah R., Gressett, Timothy E., Srivastava, Akhilesh, Dinnon, Kenneth H., Engler-Chiurazzi, Elizabeth B., Maness, Nicholas J., Qin, Xuebin, Kolls, Jay K., Baric, Ralph S., Bix, Gregory
Publicado 2022

Ex vivo and in vivo suppression of SARS-CoV-2 with combinatorial AAV/RNAi expression vectors

por Becker, Jonas, Stanifer, Megan Lynn, Leist, Sarah Rebecca, Stolp, Bettina, Maiakovska, Olena, West, Ande, Wiedtke, Ellen, Börner, Kathleen, Ghanem, Ali, Ambiel, Ina, Tse, Longping Victor, Fackler, Oliver Till, Baric, Ralph Steven, Boulant, Steeve, Grimm, Dirk
Publicado 2022

A C57BL/6 Mouse model of SARS-CoV-2 infection recapitulates age- and sex-based differences in human COVID-19 disease and recovery

por Davis, Michael, Voss, Kathleen, Turnbull, J. Bryan, Gustin, Andrew T., Knoll, Megan, Muruato, Antonio, Hsiang, Tien-Ying, Dinnon, Kenneth H., Leist, Sarah R., Nickel, Katie, Baric, Ralph S., Ladiges, Warren, Akilesh, Shreeram, Smith, Kelly D., Gale, Michael
Publicado 2022

A C57BL/6 Mouse Model of SARS-CoV-2 Infection Recapitulates Age- and Sex-Based Differences in Human COVID-19 Disease and Recovery

por Davis, Michael A., Voss, Kathleen, Turnbull, J. Bryan, Gustin, Andrew T., Knoll, Megan, Muruato, Antonio, Hsiang, Tien-Ying, Dinnon III, Kenneth H., Leist, Sarah R., Nickel, Katie, Baric, Ralph S., Ladiges, Warren, Akilesh, Shreeram, Smith, Kelly D., Gale, Michael
Publicado 2022

Antibody potency, effector function and combinations in protection from SARS-CoV-2 infection in vivo

por Schäfer, Alexandra, Muecksch, Frauke, Lorenzi, Julio C. C., Leist, Sarah R., Cipolla, Melissa, Bournazos, Stylianos, Schmidt, Fabian, Gazumyan, Anna, Baric, Ralph S., Robbiani, Davide F., Hatziioannou, Theodora, Ravetch, Jeffrey V., Bieniasz, Paul D., Nussenzweig, Michel C., Sheahan, Timothy P.
Publicado 2020

Prevention and therapy of SARS-CoV-2 and the B.1.351 variant in mice

por Martinez, David R., Schaefer, Alexandra, Leist, Sarah R., Li, Dapeng, Gully, Kendra, Yount, Boyd, Feng, Joy Y., Bunyan, Elaine, Porter, Danielle P., Cihlar, Tomas, Montgomery, Stephanie A., Haynes, Barton F., Baric, Ralph S., Nussenzweig, Michel C., Sheahan, Timothy P.
Publicado 2021