Purinergic and Calcium Signaling in Macrophage Function and Plasticity

por Desai, Bimal N., Leitinger, Norbert
Publicado 2014

NFAT5 expression in bone marrow-derived cells enhances atherosclerosis and drives macrophage migration

por Halterman, Julia A., Kwon, H. Moo, Leitinger, Norbert, Wamhoff, Brian R.
Publicado 2012

Regioisomer-independent quantification of fatty acid oxidation products by HPLC-ESI-MS/MS analysis of sodium adducts

por Ahern, Katelyn W., Serbulea, Vlad, Wingrove, Catherine L., Palas, Zachary T., Leitinger, Norbert, Harris, Thurl E.
Publicado 2019

Macrophage phenotype and bioenergetics are controlled by oxidized phospholipids identified in lean and obese adipose tissue

por Serbulea, Vlad, Upchurch, Clint M., Schappe, Michael S., Voigt, Paxton, DeWeese, Dory E., Desai, Bimal N., Meher, Akshaya K., Leitinger, Norbert
Publicado 2018

Oxidized phospholipids reduce ventilator-induced vascular leak and inflammation in vivo

por Nonas, Stephanie, Birukova, Anna A, Fu, Panfeng, Xing, Jungjie, Chatchavalvanich, Santipongse, Bochkov, Valery N, Leitinger, Norbert, Garcia, Joe GN, Birukov, Konstantin G
Publicado 2008

Innate immune signaling in Drosophila shifts anabolic lipid metabolism from triglyceride storage to phospholipid synthesis to support immune function

por Martínez, Brittany A., Hoyle, Rosalie G., Yeudall, Scott, Granade, Mitchell E., Harris, Thurl E., Castle, J. David, Leitinger, Norbert, Bland, Michelle L.
Publicado 2020

Macrophages sensing oxidized DAMPs reprogram their metabolism to support redox homeostasis and inflammation through a TLR2-Syk-ceramide dependent mechanism

por Serbulea, Vlad, Upchurch, Clint M., Ahern, Katelyn W., Bories, Gael, Voigt, Paxton, DeWeese, Dory E., Meher, Akshaya K., Harris, Thurl E., Leitinger, Norbert
Publicado 2017

Targeting oxidized phospholipids by AAV-based gene therapy in mice with established hepatic steatosis prevents progression to fibrosis

por Upchurch, Clint M., Yeudall, Scott, Pavelec, Caitlin M., Merk, Dennis, Greulich, Jan, Manjegowda, Mohan, Raghavan, Shyam S., Bochkis, Irina M., Scott, Michael M., Perez-Reyes, Edward, Leitinger, Norbert
Publicado 2022

Macrophage acetyl-CoA carboxylase regulates acute inflammation through control of glucose and lipid metabolism

por Yeudall, Scott, Upchurch, Clint M., Seegren, Philip V., Pavelec, Caitlin M., Greulich, Jan, Lemke, Michael C., Harris, Thurl E., Desai, Bimal N., Hoehn, Kyle L., Leitinger, Norbert
Publicado 2022

Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release

por Morioka, Sho, Perry, Justin S. A., Raymond, Michael H., Medina, Christopher B., Zhu, Yunlu, Zhao, Liyang, Serbulea, Vlad, Onengut-Gumuscu, Suna, Leitinger, Norbert, Kucenas, Sarah, Rathmell, Jeffrey C., Makowski, Liza, Ravichandran, Kodi S.
Publicado 2018

Pannexin 1 channels regulate leukocyte emigration through the venous endothelium during acute inflammation

por Lohman, Alexander W., Leskov, Igor L., Butcher, Joshua T., Johnstone, Scott R., Stokes, Tara A., Begandt, Daniela, DeLalio, Leon J., Best, Angela K., Penuela, Silvia, Leitinger, Norbert, Ravichandran, Kodi S., Stokes, Karen Y., Isakson, Brant E.
Publicado 2015

Mitochondrial Ca(2+) Signaling Is an Electrometabolic Switch to Fuel Phagosome Killing

por Seegren, Philip V., Downs, Taylor K., Stremska, Marta E., Harper, Logan R., Cao, Ruofan, Olson, Rachel J., Upchurch, Clint M., Doyle, Catherine A., Kennedy, Joel, Stipes, Eric L., Leitinger, Norbert, Periasamy, Ammasi, Desai, Bimal N.
Publicado 2020

Iron control of erythroid microtubule cytoskeleton as a potential target in treatment of iron-restricted anemia

por Goldfarb, Adam N., Freeman, Katie C., Sahu, Ranjit K., Elagib, Kamaleldin E., Holy, Maja, Arneja, Abhinav, Polanowska-Grabowska, Renata, Gru, Alejandro A., White, Zollie, Khalil, Shadi, Kerins, Michael J., Ooi, Aikseng, Leitinger, Norbert, Luckey, Chance John, Delehanty, Lorrie L.
Publicado 2021

Pannexin 1 is required for full activation of insulin-stimulated glucose uptake in adipocytes

por Adamson, Samantha E., Meher, Akshaya K., Chiu, Yu-hsin, Sandilos, Joanna K., Oberholtzer, Nathaniel P., Walker, Natalie N., Hargett, Stefan R., Seaman, Scott A., Peirce-Cottler, Shayn M., Isakson, Brant E., McNamara, Coleen A., Keller, Susanna R., Harris, Thurl E., Bayliss, Douglas A., Leitinger, Norbert
Publicado 2015

Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2

por Kreutzberger, Alex J B, Kiessling, Volker, Doyle, Catherine A, Schenk, Noah, Upchurch, Clint M, Elmer-Dixon, Margaret, Ward, Amanda E, Preobraschenski, Julia, Hussein, Syed S, Tomaka, Weronika, Seelheim, Patrick, Kattan, Iman, Harris, Megan, Liang, Binyong, Kenworthy, Anne K, Desai, Bimal N, Leitinger, Norbert, Anantharam, Arun, Castle, J David, Tamm, Lukas K
Publicado 2020

Adaptive thermogenesis in brown adipose tissue involves activation of pannexin-1 channels

por Senthivinayagam, Subramanian, Serbulea, Vlad, Upchurch, Clint M., Polanowska-Grabowska, Renata, Mendu, Suresh K., Sahu, Srabani, Jayaguru, Prathiba, Aylor, Kevin W., Chordia, Mahendra D., Steinberg, Limor, Oberholtzer, Nathaniel, Uchiyama, Seichii, Inada, Noriko, Lorenz, Ulrike M., Harris, Thurl E., Keller, Susanna R., Meher, Akshaya K., Kadl, Alexandra, Desai, Bimal N., Kundu, Bijoy K., Leitinger, Norbert
Publicado 2020

Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development

por Ambati, Jayakrishna, Magagnoli, Joseph, Leung, Hannah, Wang, Shao-bin, Andrews, Chris A., Fu, Dongxu, Pandey, Akshat, Sahu, Srabani, Narendran, Siddharth, Hirahara, Shuichiro, Fukuda, Shinichi, Sun, Jian, Pandya, Lekha, Ambati, Meenakshi, Pereira, Felipe, Varshney, Akhil, Cummings, Tammy, Hardin, James W., Edun, Babatunde, Bennett, Charles L., Ambati, Kameshwari, Fowler, Benjamin J., Kerur, Nagaraj, Röver, Christian, Leitinger, Norbert, Werner, Brian C., Stein, Joshua D., Sutton, S. Scott, Gelfand, Bradley D.
Publicado 2020

cGAS drives non-canonical inflammasome activation in age-related macular degeneration

por Kerur, Nagaraj, Fukuda, Shinichi, Banerjee, Daipayan, Kim, Younghee, Fu, Dongxu, Apicella, Ivana, Varshney, Akhil, Yasuma, Reo, Fowler, Benjamin J., Baghdasaryan, Elmira, Marion, Kenneth M., Huang, Xiwen, Yasuma, Tetsuhiro, Hirano, Yoshio, Serbulea, Vlad, Ambati, Meenakshi, Ambati, Vidya L., Kajiwara, Yuji, Ambati, Kameshwari, Bastos-Carvalho, Ana, Ogura, Yuichiro, Terasaki, Hiroko, Oshika, Tetsuro, Kim, Kyung Bo, Hinton, David R., Leitinger, Norbert, Cambier, John C., Buxbaum, Joseph D., Kenney, M. Cristina, Jazwinski, S. Michal, Nagai, Hiroshi, Hara, Isao, West, A. Phillip, Fitzgerald, Katherine A., Sadda, SriniVas R., Gelfand, Bradley D., Ambati, Jayakrishna
Publicado 2017