Bortezomib inhibits chikungunya virus replication by interfering with viral protein synthesis

por Kaur, Parveen, Lello, Laura Sandra, Utt, Age, Dutta, Sujit Krishna, Merits, Andres, Chu, Justin Jang Hann
Publicado 2020

Activity, Template Preference, and Compatibility of Components of RNA Replicase of Eastern Equine Encephalitis Virus

por Lello, Laura Sandra, Miilimäe, Agneta, Cherkashchenko, Liubov, Omler, Ailar, Skilton, Rachel, Ireland, Rachel, Ulaeto, David, Merits, Andres
Publicado 2022

nsP4 Is a Major Determinant of Alphavirus Replicase Activity and Template Selectivity

por Lello, Laura Sandra, Bartholomeeusen, Koen, Wang, Sainan, Coppens, Sandra, Fragkoudis, Rennos, Alphey, Luke, Ariën, Kevin K., Merits, Andres, Utt, Age
Publicado 2021

Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold

por Tan, Yaw Bia, Lello, Laura Sandra, Liu, Xin, Law, Yee-Song, Kang, Congbao, Lescar, Julien, Zheng, Jie, Merits, Andres, Luo, Dahai
Publicado 2022

Cross-utilisation of template RNAs by alphavirus replicases

por Lello, Laura Sandra, Utt, Age, Bartholomeeusen, Koen, Wang, Sainan, Rausalu, Kai, Kendall, Catherine, Coppens, Sandra, Fragkoudis, Rennos, Tuplin, Andrew, Alphey, Luke, Ariën, Kevin K., Merits, Andres
Publicado 2020

Synergistic Interferon-Alpha-Based Combinations for Treatment of SARS-CoV-2 and Other Viral Infections

por Ianevski, Aleksandr, Yao, Rouan, Zusinaite, Eva, Lello, Laura Sandra, Wang, Sainan, Jo, Eunji, Yang, Jaewon, Ravlo, Erlend, Wang, Wei, Lysvand, Hilde, Løseth, Kirsti, Oksenych, Valentyn, Tenson, Tanel, Windisch, Marc P., Poranen, Minna M., Nieminen, Anni I., Nordbø, Svein Arne, Fenstad, Mona Høysæter, Grødeland, Gunnveig, Aukrust, Pål, Trøseid, Marius, Kantele, Anu, Lastauskienė, Eglė, Vitkauskienė, Astra, Legrand, Nicolas, Merits, Andres, Bjørås, Magnar, Kainov, Denis E.
Publicado 2021

Bovine colostrum-derived antibodies against SARS-CoV-2 show great potential to serve as prophylactic agents

por Kangro, Kadri, Kurašin, Mihhail, Gildemann, Kiira, Sankovski, Eve, Žusinaite, Eva, Lello, Laura Sandra, Pert, Raini, Kavak, Ants, Poikalainen, Väino, Lepasalu, Lembit, Kuusk, Marilin, Pau, Robin, Piiskop, Sander, Rom, Siimu, Oltjer, Ruth, Tiirik, Kairi, Kogermann, Karin, Plaas, Mario, Tiirats, Toomas, Aasmäe, Birgit, Plaas, Mihkel, Mumm, Karl, Krinka, Dagni, Talpsep, Ene, Kadaja, Meelis, Gerhold, Joachim M., Planken, Anu, Tover, Andres, Merits, Andres, Männik, Andres, Ustav, Mart, Ustav, Mart
Publicado 2022

A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research

por Rihn, Suzannah J., Merits, Andres, Bakshi, Siddharth, Turnbull, Matthew L., Wickenhagen, Arthur, Alexander, Akira J. T., Baillie, Carla, Brennan, Benjamin, Brown, Fiona, Brunker, Kirstyn, Bryden, Steven R., Burness, Kerry A., Carmichael, Stephen, Cole, Sarah J., Cowton, Vanessa M., Davies, Paul, Davis, Chris, De Lorenzo, Giuditta, Donald, Claire L., Dorward, Mark, Dunlop, James I., Elliott, Matthew, Fares, Mazigh, da Silva Filipe, Ana, Freitas, Joseph R., Furnon, Wilhelm, Gestuveo, Rommel J., Geyer, Anna, Giesel, Daniel, Goldfarb, Daniel M., Goodman, Nicola, Gunson, Rory, Hastie, C. James, Herder, Vanessa, Hughes, Joseph, Johnson, Clare, Johnson, Natasha, Kohl, Alain, Kerr, Karen, Leech, Hannah, Lello, Laura Sandra, Li, Kathy, Lieber, Gauthier, Liu, Xiang, Lingala, Rajendra, Loney, Colin, Mair, Daniel, McElwee, Marion J., McFarlane, Steven, Nichols, Jenna, Nomikou, Kyriaki, Orr, Anne, Orton, Richard J., Palmarini, Massimo, Parr, Yasmin A., Pinto, Rute Maria, Raggett, Samantha, Reid, Elaine, Robertson, David L., Royle, Jamie, Cameron-Ruiz, Natalia, Shepherd, James G., Smollett, Katherine, Stewart, Douglas G., Stewart, Meredith, Sugrue, Elena, Szemiel, Agnieszka M., Taggart, Aislynn, Thomson, Emma C., Tong, Lily, Torrie, Leah S., Toth, Rachel, Varjak, Margus, Wang, Sainan, Wilkinson, Stuart G., Wyatt, Paul G., Zusinaite, Eva, Alessi, Dario R., Patel, Arvind H., Zaid, Ali, Wilson, Sam J., Mahalingam, Suresh
Publicado 2021