How Semiphysiological Population Pharmacokinetic Modeling Incorporating Active Hepatic Uptake Supports Phase II Dose Selection of RO7049389, A Novel Anti–Hepatitis B Virus Drug

por Cosson, Valérie, Feng, Sheng, Jaminion, Felix, Lemenuel‐Diot, Annabelle, Parrott, Neil, Paehler, Axel, Bo, Qingyan, Jin, Yuyan
Publicado 2021

Pharmacologic effects of oseltamivir in immunocompromised adult patients as assessed by population PK/PD analysis and drug‐disease modelling for dosing regimen optimization

por Sturm, Stefan, Lemenuel‐Diot, Annabelle, Patel, Kashyap, Gibiansky, Leonid, Bhardwaj, Rajinder, Smith, Patrick F., Dang, Steve, Zwanziger, Elke, Nasmyth‐Miller, Clare, Ravva, Patanjali
Publicado 2020

Novel modelling approaches to predict the role of antivirals in reducing influenza transmission

por Asher, Jason, Lemenuel-Diot, Annabelle, Clay, Matthew, Durham, David P., Mier-y-Teran-Romero, Luis, Arguello, Carlos J., Jolivet, Sebastien, Wong, Diana Y., Kuhlbusch, Klaus, Clinch, Barry, Charoin, Jean-Eric
Publicado 2023

Reducing Influenza Virus Transmission: The Potential Value of Antiviral Treatment

por Hayden, Frederick G, Asher, Jason, Cowling, Benjamin J, Hurt, Aeron C, Ikematsu, Hideyuki, Kuhlbusch, Klaus, Lemenuel-Diot, Annabelle, Du, Zhanwei, Meyers, Lauren Ancel, Piedra, Pedro A, Takazono, Takahiro, Yen, Hui-Ling, Monto, Arnold S
Publicado 2021

Clinical Study of Single‐Stranded Oligonucleotide RO7062931 in Healthy Volunteers and Patients With Chronic Hepatitis B

por Gane, Edward, Yuen, Man‐Fung, Kim, Dong Joon, Chan, Henry Lik‐Yuen, Surujbally, Bernadette, Pavlovic, Vedran, Das, Sudip, Triyatni, Miriam, Kazma, Remi, Grippo, Joseph F., Buatois, Simon, Lemenuel‐Diot, Annabelle, Krippendorff, Ben‐Fillippo, Mueller, Henrik, Zhang, Yuchen, Kim, Hyung Joon, Leerapun, Apinya, Lim, Tien Huey, Lim, Young‐Suk, Tanwandee, Tawesak, Kim, Won, Cheng, Wendy, Hu, Tsung‐Hui, Wat, Cynthia
Publicado 2021