Surgical Management of Acute Abdomen in Adult Patients: Experience from a Private Hospital in Addis Ababa, Ethiopia

por Ademe, Yonas, Seyoum, Nebyou, Lemma, Rakeb
Publicado 2022

DIPG-79. H3K27M INDUCES EPIGENETIC AND ONCOGENIC CHANGES THAT ARE PARTIALLY REVERSED BY SMALL MOLECULE AURORA KINASE B/C INHIBITION

por Chatwin, Hannah, Lemma, Rakeb, DeSisto, John, Knox, Aaron, Mestnik, Shelby, Reid, Aidan, Vibhakar, Rajeev, Venkataraman, Sujatha, Green, Adam
Publicado 2020

MODL-31. RADIATION-DERIVED TREATMENT-RESISTANT PDX AND CELL CULTURE MODELS RECAPITULATE THE CHARACTERISTICS OF MATCHED PRIMARY/RECURRENT PEDIATRIC HIGH-GRADE GLIOMA

por Knox, Aaron J, Flannery, Patrick, Zukosky, Anjali, DeSisto, John, Sanford, Bridget, van Court, Benjamin, Donson, Andrew, Lemma, Rakeb, Chatwin, Hannah, Karam, Sana D, Vibhakar, Rajeev, Jones, Ken, Green, Adam L
Publicado 2020

Preclinical analysis of MTOR complex 1/2 inhibition in diffuse intrinsic pontine glioma

por Flannery, Patrick C., Desisto, John A., Amani, Vladimir, Venkataraman, Sujatha, Lemma, Rakeb T., Prince, Eric W., Donson, Andrew, Moroze, Erin E., Hoffman, Lindsey, Levy, Jean M. Mulcahy, Foreman, Nicholas, Vibhakar, Rajeev, Green, Adam L.
Publicado 2018

A novel preclinical model of craniospinal irradiation in pediatric diffuse midline glioma demonstrates decreased metastatic disease

por Knox, Aaron J., Van Court, Benjamin, Oweida, Ayman, Barsh, Elinor, DeSisto, John, Flannery, Patrick, Lemma, Rakeb, Chatwin, Hannah, Vibhakar, Rajeev, Dorris, Kathleen, Serkova, Natalie J., Karam, Sana D., Gilani, Ahmed, Green, Adam L.
Publicado 2023

DIPG-42. TOWARD MULTIMODALITY THERAPY FOR DIPG/DMG: DEVELOPMENT AND INVESTIGATION OF CRANIOSPINAL IRRADIATION AND CONVECTION-ENHANCED DELIVERY PDX MODELS

por Knox, Aaron J, Gilani, Ahmed, van Court, Benjamin, Oweida, Ayman, Flannery, Patrick, DeSisto, John, Lemma, Rakeb, Chatwin, Hannah, Gamboni, Fabia, Brown, Benjamin, Serkova, Natalie, Vibhakar, Rajeev, Dorris, Kathleen, Wempe, Michael, Reisz, Julie A, Karam, Sana D, Green, Adam L
Publicado 2020

Preclinical and clinical investigation of intratumoral chemotherapy pharmacokinetics in DIPG using gemcitabine

por Green, Adam L, Flannery, Patrick, Hankinson, Todd C, O’Neill, Brent, Amani, Vladimir, DeSisto, John, Knox, Aaron, Chatwin, Hannah, Lemma, Rakeb, Hoffman, Lindsey M, Mulcahy Levy, Jean, Raybin, Jennifer, Hemenway, Molly, Gilani, Ahmed, Koschmann, Carl, Dahl, Nathan, Handler, Michael, Pierce, Angela, Venkataraman, Sujatha, Foreman, Nicholas, Vibhakar, Rajeev, Wempe, Michael F, Dorris, Kathleen
Publicado 2020

HGG-57. WHOLE-GENOME SEQUENCING, METHYLATION ANALYSIS, AND SINGLE-CELL RNA-SEQ DEFINE UNIQUE CHARACTERISTICS OF PEDIATRIC TREATMENT-INDUCED HIGH-GRADE GLIOMA AND SUGGEST ONCOGENIC...

por Lucas, John, DeSisto, John, Xu, Ke, Donson, Andrew, Lin, Tong, Sanford, Bridget, Wu, Gang, Tran, Quynh, Hedges, Dale, Hsu, Chih-Yang, Armstrong, Gregory, Arnold, Michael, Bhatia, Smita, Flannery, Patrick, Lemma, Rakeb, Hardie, Lakotah, Schuller, Ulrich, Hoffman, Lindsey, Dorris, Kathleen, Levy, Jean, Hankinson, Todd, Handler, Michael, Liu, Arthur, Foreman, Nicholas, Vibhakar, Rajeev, Jones, Kenneth, Allen, Sariah, Zhang, Jinghui, Baker, Suzanne, Merchant, Thomas, Orr, Brent, Green, Adam
Publicado 2020

Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG

por Balakrishnan, Ilango, Danis, Etienne, Pierce, Angela, Madhavan, Krishna, Wang, Dong, Dahl, Nathan, Sanford, Bridget, Birks, Diane K., Davidson, Nate, Metselaar, Dennis S., Meel, Michaël Hananja, Lemma, Rakeb, Donson, Andrew, Vijmasi, Trinka, Katagi, Hiroaki, Sola, Ismail, Fosmire, Susan, Alimova, Irina, Steiner, Jenna, Gilani, Ahmed, Hulleman, Esther, Serkova, Natalie J., Hashizume, Rintaro, Hawkins, Cynthia, Carcaboso, Angel M., Gupta, Nalin, Monje, Michelle, Jabado, Nada, Jones, Kenneth, Foreman, Nicholas, Green, Adam, Vibhakar, Rajeev, Venkataraman, Sujatha
Publicado 2020

BPTF Regulates Growth of Adult and Pediatric High-Grade Glioma through the MYC Pathway

por Green, Adam L., DeSisto, John, Flannery, Patrick, Lemma, Rakeb, Knox, Aaron, Lemieux, Madeleine, Sanford, Bridget, O’Rourke, Rebecca, Ramkissoon, Shakti, Jones, Kristen, Perry, Jennifer, Hui, Xu, Moroze, Erin, Balakrishnan, Ilango, O’Neill, Allison F., Dunn, Katherine, DeRyckere, Deborah, Danis, Etienne, Safadi, Aaron, Gilani, Ahmed, Hubbell-Engler, Benjamin, Nuss, Zachary, Mulcahy Levy, Jean M., Serkova, Natalie, Venkataraman, Sujatha, Graham, Douglas K., Foreman, Nicholas, Ligon, Keith, Jones, Ken, Kung, Andrew, Vibhakar, Rajeev
Publicado 2019

Comprehensive molecular characterization of pediatric radiation-induced high-grade glioma

por DeSisto, John, Lucas, John T., Xu, Ke, Donson, Andrew, Lin, Tong, Sanford, Bridget, Wu, Gang, Tran, Quynh T., Hedges, Dale, Hsu, Chih-Yang, Armstrong, Gregory T., Arnold, Michael, Bhatia, Smita, Flannery, Patrick, Lemma, Rakeb, Hardie, Lakotah, Schüller, Ulrich, Venkataraman, Sujatha, Hoffman, Lindsey M., Dorris, Kathleen, Mulcahy Levy, Jean M., Hankinson, Todd C., Handler, Michael, Liu, Arthur K., Foreman, Nicholas, Vibhakar, Rajeev, Jones, Kenneth, Allen, Sariah, Zhang, Jinghui, Baker, Suzanne J., Merchant, Thomas E., Orr, Brent A., Green, Adam L.
Publicado 2021