Mouse Model of Cytomegalovirus Disease and Immunotherapy in the Immunocompromised Host: Predictions for Medical Translation that Survived the “Test of Time”

por Reddehase, Matthias J., Lemmermann, Niels A. W.
Publicado 2018

Direct Evidence for Viral Antigen Presentation during Latent Cytomegalovirus Infection

por Lemmermann, Niels A. W., Reddehase, Matthias J.
Publicado 2021

Mast Cells Meet Cytomegalovirus: A New Example of Protective Mast Cell Involvement in an Infectious Disease

por Becker, Sara, Reddehase, Matthias J., Lemmermann, Niels A.
Publicado 2022

Consequence of Histoincompatibility beyond GvH-Reaction in Cytomegalovirus Disease Associated with Allogeneic Hematopoietic Cell Transplantation: Change of Paradigm

por Reddehase, Matthias J., Holtappels, Rafaela, Lemmermann, Niels A. W.
Publicado 2021

The p36 Isoform of Murine Cytomegalovirus m152 Protein Suffices for Mediating Innate and Adaptive Immune Evasion

por Fink, Annette, Renzaho, Angeliqué, Reddehase, Matthias J., Lemmermann, Niels A. W.
Publicado 2013

Localization of Viral Epitope-Specific CD8 T Cells during Cytomegalovirus Latency in the Lungs and Recruitment to Lung Parenchyma by Airway Challenge Infection

por Blaum, Franziska, Lukas, Dominika, Reddehase, Matthias J., Lemmermann, Niels A. W.
Publicado 2021

Host-Adapted Gene Families Involved in Murine Cytomegalovirus Immune Evasion

por Becker, Sara, Fink, Annette, Podlech, Jürgen, Reddehase, Matthias J., Lemmermann, Niels A.
Publicado 2022

Memory CD8 T Cells Protect against Cytomegalovirus Disease by Formation of Nodular Inflammatory Foci Preventing Intra-Tissue Virus Spread

por Holtappels, Rafaela, Podlech, Jürgen, Freitag, Kirsten, Lemmermann, Niels A., Reddehase, Matthias J.
Publicado 2022

Reconstitution of CD8 T Cells Protective against Cytomegalovirus in a Mouse Model of Hematopoietic Cell Transplantation: Dynamics and Inessentiality of Epitope Immunodominance

por Holtappels, Rafaela, Lemmermann, Niels A. W., Podlech, Jürgen, Ebert, Stefan, Reddehase, Matthias J.
Publicado 2016

Cytomegalovirus-Associated Inhibition of Hematopoiesis Is Preventable by Cytoimmunotherapy With Antiviral CD8 T Cells

por Renzaho, Angelique, Podlech, Jürgen, Kühnapfel, Birgit, Blaum, Franziska, Reddehase, Matthias J., Lemmermann, Niels A. W.
Publicado 2020

Revisiting CD8 T-cell ‘Memory Inflation’: New Insights with Implications for Cytomegaloviruses as Vaccine Vectors

por Holtappels, Rafaela, Freitag, Kirsten, Renzaho, Angelique, Becker, Sara, Lemmermann, Niels A.W., Reddehase, Matthias J.
Publicado 2020

Immunotherapy of cytomegalovirus infection by low-dose adoptive transfer of antiviral CD8 T cells relies on substantial post-transfer expansion of central memory cells but not effe...

por Holtappels, Rafaela, Becker, Sara, Hamdan, Sara, Freitag, Kirsten, Podlech, Jürgen, Lemmermann, Niels A., Reddehase, Matthias J.
Publicado 2023

Noncanonical Expression of a Murine Cytomegalovirus Early Protein CD8 T-Cell Epitope as an Immediate Early Epitope Based on Transcription from an Upstream Gene

por Fink, Annette, Büttner, Julia K., Thomas, Doris, Holtappels, Rafaela, Reddehase, Matthias J., Lemmermann, Niels A. W.
Publicado 2014

Enhancement of Antigen Presentation by Deletion of Viral Immune Evasion Genes Prevents Lethal Cytomegalovirus Disease in Minor Histocompatibility Antigen-Mismatched Hematopoietic C...

por Gezinir, Emin, Podlech, Jürgen, Gergely, Kerstin M., Becker, Sara, Reddehase, Matthias J., Lemmermann, Niels A. W.
Publicado 2020

The Anti-apoptotic Murine Cytomegalovirus Protein vMIA-m38.5 Induces Mast Cell Degranulation

por Schmiedeke, Julia K., Hartmann, Ann-Kathrin, Ruckenbrod, Teresa, Stassen, Michael, Reddehase, Matthias J., Lemmermann, Niels A.
Publicado 2020

Stochastic Episodes of Latent Cytomegalovirus Transcription Drive CD8 T-Cell “Memory Inflation” and Avoid Immune Evasion

por Griessl, Marion, Renzaho, Angelique, Freitag, Kirsten, Seckert, Christof K., Reddehase, Matthias J., Lemmermann, Niels A. W.
Publicado 2021

Reverse Genetics Modification of Cytomegalovirus Antigenicity and Immunogenicity by CD8 T-Cell Epitope Deletion and Insertion

por Lemmermann, Niels A. W., Kropp, Kai A., Seckert, Christof K., Grzimek, Natascha K. A., Reddehase, Matthias J.
Publicado 2011

Insufficient Antigen Presentation Due to Viral Immune Evasion Explains Lethal Cytomegalovirus Organ Disease After Allogeneic Hematopoietic Cell Transplantation

por Holtappels, Rafaela, Schader, Sina I., Oettel, Oliver, Podlech, Jürgen, Seckert, Christof K., Reddehase, Matthias J., Lemmermann, Niels A. W.
Publicado 2020

Positive Role of the MHC Class-I Antigen Presentation Regulator m04/gp34 of Murine Cytomegalovirus in Antiviral Protection by CD8 T Cells

por Becker, Sara, Fink, Annette, Podlech, Jürgen, Giese, Irina, Schmiedeke, Julia K., Bukur, Thomas, Reddehase, Matthias J., Lemmermann, Niels A.
Publicado 2020

The herpesviral antagonist m152 reveals differential activation of STING‐dependent IRF and NF‐κB signaling and STING's dual role during MCMV infection

por Stempel, Markus, Chan, Baca, Juranić Lisnić, Vanda, Krmpotić, Astrid, Hartung, Josephine, Paludan, Søren R, Füllbrunn, Nadia, Lemmermann, Niels AW, Brinkmann, Melanie M
Publicado 2019