Mouse Model of Cytomegalovirus Disease and Immunotherapy in the Immunocompromised Host: Predictions for Medical Translation that Survived the “Test of Time”

por Reddehase, Matthias J., Lemmermann, Niels A. W.
Publicado 2018

Direct Evidence for Viral Antigen Presentation during Latent Cytomegalovirus Infection

por Lemmermann, Niels A. W., Reddehase, Matthias J.
Publicado 2021

Consequence of Histoincompatibility beyond GvH-Reaction in Cytomegalovirus Disease Associated with Allogeneic Hematopoietic Cell Transplantation: Change of Paradigm

por Reddehase, Matthias J., Holtappels, Rafaela, Lemmermann, Niels A. W.
Publicado 2021

The p36 Isoform of Murine Cytomegalovirus m152 Protein Suffices for Mediating Innate and Adaptive Immune Evasion

por Fink, Annette, Renzaho, Angeliqué, Reddehase, Matthias J., Lemmermann, Niels A. W.
Publicado 2013

Localization of Viral Epitope-Specific CD8 T Cells during Cytomegalovirus Latency in the Lungs and Recruitment to Lung Parenchyma by Airway Challenge Infection

por Blaum, Franziska, Lukas, Dominika, Reddehase, Matthias J., Lemmermann, Niels A. W.
Publicado 2021

Reconstitution of CD8 T Cells Protective against Cytomegalovirus in a Mouse Model of Hematopoietic Cell Transplantation: Dynamics and Inessentiality of Epitope Immunodominance

por Holtappels, Rafaela, Lemmermann, Niels A. W., Podlech, Jürgen, Ebert, Stefan, Reddehase, Matthias J.
Publicado 2016

Cytomegalovirus-Associated Inhibition of Hematopoiesis Is Preventable by Cytoimmunotherapy With Antiviral CD8 T Cells

por Renzaho, Angelique, Podlech, Jürgen, Kühnapfel, Birgit, Blaum, Franziska, Reddehase, Matthias J., Lemmermann, Niels A. W.
Publicado 2020

Revisiting CD8 T-cell ‘Memory Inflation’: New Insights with Implications for Cytomegaloviruses as Vaccine Vectors

por Holtappels, Rafaela, Freitag, Kirsten, Renzaho, Angelique, Becker, Sara, Lemmermann, Niels A.W., Reddehase, Matthias J.
Publicado 2020

Noncanonical Expression of a Murine Cytomegalovirus Early Protein CD8 T-Cell Epitope as an Immediate Early Epitope Based on Transcription from an Upstream Gene

por Fink, Annette, Büttner, Julia K., Thomas, Doris, Holtappels, Rafaela, Reddehase, Matthias J., Lemmermann, Niels A. W.
Publicado 2014

Enhancement of Antigen Presentation by Deletion of Viral Immune Evasion Genes Prevents Lethal Cytomegalovirus Disease in Minor Histocompatibility Antigen-Mismatched Hematopoietic C...

por Gezinir, Emin, Podlech, Jürgen, Gergely, Kerstin M., Becker, Sara, Reddehase, Matthias J., Lemmermann, Niels A. W.
Publicado 2020

Stochastic Episodes of Latent Cytomegalovirus Transcription Drive CD8 T-Cell “Memory Inflation” and Avoid Immune Evasion

por Griessl, Marion, Renzaho, Angelique, Freitag, Kirsten, Seckert, Christof K., Reddehase, Matthias J., Lemmermann, Niels A. W.
Publicado 2021

Reverse Genetics Modification of Cytomegalovirus Antigenicity and Immunogenicity by CD8 T-Cell Epitope Deletion and Insertion

por Lemmermann, Niels A. W., Kropp, Kai A., Seckert, Christof K., Grzimek, Natascha K. A., Reddehase, Matthias J.
Publicado 2011

Insufficient Antigen Presentation Due to Viral Immune Evasion Explains Lethal Cytomegalovirus Organ Disease After Allogeneic Hematopoietic Cell Transplantation

por Holtappels, Rafaela, Schader, Sina I., Oettel, Oliver, Podlech, Jürgen, Seckert, Christof K., Reddehase, Matthias J., Lemmermann, Niels A. W.
Publicado 2020

Evaluating Human T-Cell Therapy of Cytomegalovirus Organ Disease in HLA-Transgenic Mice

por Thomas, Simone, Klobuch, Sebastian, Podlech, Jürgen, Plachter, Bodo, Hoffmann, Petra, Renzaho, Angelique, Theobald, Matthias, Reddehase, Matthias J., Herr, Wolfgang, Lemmermann, Niels A. W.
Publicado 2015

Therapeutic Vaccination of Hematopoietic Cell Transplantation Recipients Improves Protective CD8 T-Cell Immunotherapy of Cytomegalovirus Infection

por Gergely, Kerstin M., Podlech, Jürgen, Becker, Sara, Freitag, Kirsten, Krauter, Steffi, Büscher, Nicole, Holtappels, Rafaela, Plachter, Bodo, Reddehase, Matthias J., Lemmermann, Niels A. W.
Publicado 2021

Non-redundant and Redundant Roles of Cytomegalovirus gH/gL Complexes in Host Organ Entry and Intra-tissue Spread

por Lemmermann, Niels A. W., Krmpotic, Astrid, Podlech, Jürgen, Brizic, Ilija, Prager, Adrian, Adler, Heiko, Karbach, Astrid, Wu, Yiquan, Jonjic, Stipan, Reddehase, Matthias J., Adler, Barbara
Publicado 2015

Coincident airway exposure to low-potency allergen and cytomegalovirus sensitizes for allergic airway disease by viral activation of migratory dendritic cells

por Reuter, Sebastian, Lemmermann, Niels A. W., Maxeiner, Joachim, Podlech, Jürgen, Beckert, Hendrik, Freitag, Kirsten, Teschner, Daniel, Ries, Frederic, Taube, Christian, Buhl, Roland, Reddehase, Matthias J., Holtappels, Rafaela
Publicado 2019

Mast Cells Expedite Control of Pulmonary Murine Cytomegalovirus Infection by Enhancing the Recruitment of Protective CD8 T Cells to the Lungs

por Ebert, Stefan, Becker, Marc, Lemmermann, Niels A. W., Büttner, Julia K., Michel, Anastasija, Taube, Christian, Podlech, Jürgen, Böhm, Verena, Freitag, Kirsten, Thomas, Doris, Holtappels, Rafaela, Reddehase, Matthias J., Stassen, Michael
Publicado 2014

The Mouse Cytomegalovirus Gene m42 Targets Surface Expression of the Protein Tyrosine Phosphatase CD45 in Infected Macrophages

por Thiel, Nadine, Keyser, Kirsten A., Lemmermann, Niels A. W., Oduro, Jennifer D., Wagner, Karen, Elsner, Carina, Halenius, Anne, Lenac Roviš, Tihana, Brinkmann, Melanie M., Jonjić, Stipan, Cicin-Sain, Luka, Messerle, Martin
Publicado 2016

The murine cytomegalovirus M35 protein antagonizes type I IFN induction downstream of pattern recognition receptors by targeting NF-κB mediated transcription

por Chan, Baca, Gonçalves Magalhães, Vladimir, Lemmermann, Niels A. W., Juranić Lisnić, Vanda, Stempel, Markus, Bussey, Kendra A., Reimer, Elisa, Podlech, Jürgen, Lienenklaus, Stefan, Reddehase, Matthias J., Jonjić, Stipan, Brinkmann, Melanie M.
Publicado 2017