Helix-helix interactions inside lipid bilayers

por Lemmon, Mark A., Engelman, Donald M.
Publicado 1992

ErbB2/HER2/Neu resembles an autoinhibited invertebrate EGF receptor

por Alvarado, Diego, Klein, Daryl E., Lemmon, Mark A.
Publicado 2009

Ligand regulation of a constitutively dimeric EGF receptor

por Freed, Daniel M., Alvarado, Diego, Lemmon, Mark A.
Publicado 2015

Assessing the range of kinase autoinhibition mechanisms in the insulin receptor family

por Artim, Stephen C., Mendrola, Jeannine M., Lemmon, Mark A.
Publicado 2012

Erlotinib binds both inactive and active conformations of the EGFR tyrosine kinase domain

por Park, Jin H., Liu, Yingting, Lemmon, Mark A., Radhakrishnan, Ravi
Publicado 2012

Phosphatidylserine binding directly regulates TIM-3 function

por Smith, Courtney M., Li, Alice, Krishnamurthy, Nithya, Lemmon, Mark A.
Publicado 2021

Allosteric activation of the co-receptor BAK1 by the EFR receptor kinase initiates immune signaling

por Mühlenbeck, Henning, Tsutsui, Yuko, Lemmon, Mark A., Bender, Kyle W., Zipfel, Cyril
Publicado 2023

Live cell imaging with protein domains capable of recognizing phosphatidylinositol 4,5-bisphosphate; a comparative study

por Szentpetery, Zsofia, Balla, Andras, Kim, Yeun Ju, Lemmon, Mark A, Balla, Tamas
Publicado 2009

Mutations in or near the Transmembrane Domain Alter PMEL Amyloid Formation from Functional to Pathogenic

por Watt, Brenda, Tenza, Danièle, Lemmon, Mark A., Kerje, Susanne, Raposo, Graça, Andersson, Leif, Marks, Michael S.
Publicado 2011

Overcoming Resistance to HER2 Inhibitors Through State-Specific Kinase Binding

por Novotny, Chris J., Pollari, Sirkku, Park, Jin H., Lemmon, Mark A., Shen, Weijun, Shokat, Kevan M.
Publicado 2016

Computational studies of anaplastic lymphoma kinase mutations reveal common mechanisms of oncogenic activation

por Patil, Keshav, Jordan, Earl Joseph, Park, Jin H., Suresh, Krishna, Smith, Courtney M., Lemmon, Abigail A., Mossé, Yaël P., Lemmon, Mark A., Radhakrishnan, Ravi
Publicado 2021

Role of Inn1 and its interactions with Hof1 and Cyk3 in promoting cleavage furrow and septum formation in S. cerevisiae

por Nishihama, Ryuichi, Schreiter, Jennifer H., Onishi, Masayuki, Vallen, Elizabeth A., Hanna, Julia, Moravcevic, Katarina, Lippincott, Margaret F., Han, Haesun, Lemmon, Mark A., Pringle, John R., Bi, Erfei
Publicado 2009

EGFR mutations cause a lethal syndrome of epithelial dysfunction with progeroid features

por Ganetzky, Rebecca, Finn, Erin, Bagchi, Atrish, Zollo, Ornella, Conlin, Laura, Deardorff, Matthew, Harr, Margaret, Simpson, Michael A, McGrath, John A, Zackai, Elaine, Lemmon, Mark A, Sondheimer, Neal
Publicado 2015

Biochemical and structural basis for differential inhibitor sensitivity of EGFR with distinct exon 19 mutations

por van Alderwerelt van Rosenburgh, Iris K., Lu, David M., Grant, Michael J., Stayrook, Steven E., Phadke, Manali, Walther, Zenta, Goldberg, Sarah B., Politi, Katerina, Lemmon, Mark A., Ashtekar, Kumar D., Tsutsui, Yuko
Publicado 2022

Circulating tumor DNA reveals mechanisms of lorlatinib resistance in patients with relapsed/refractory ALK-driven neuroblastoma

por Berko, Esther R., Witek, Gabriela M., Matkar, Smita, Petrova, Zaritza O., Wu, Megan A., Smith, Courtney M., Daniels, Alex, Kalna, Joshua, Kennedy, Annie, Gostuski, Ivan, Casey, Colleen, Krytska, Kateryna, Gerelus, Mark, Pavlick, Dean, Ghazarian, Susan, Park, Julie R., Marachelian, Araz, Maris, John M., Goldsmith, Kelly C., Radhakrishnan, Ravi, Lemmon, Mark A., Mossé, Yaël P.
Publicado 2023

Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE

por Chongsaritsinsuk, Joann, Steigmeyer, Alexandra D., Mahoney, Keira E., Rosenfeld, Mia A., Lucas, Taryn M., Smith, Courtney M., Li, Alice, Ince, Deniz, Kearns, Fiona L., Battison, Alexandria S., Hollenhorst, Marie A., Judy Shon, D., Tiemeyer, Katherine H., Attah, Victor, Kwon, Catherine, Bertozzi, Carolyn R., Ferracane, Michael J., Lemmon, Mark A., Amaro, Rommie E., Malaker, Stacy A.
Publicado 2023