Are atrial human pluripotent stem cell-derived cardiomyocytes ready to identify drugs that beat atrial fibrillation?

por Christ, Torsten, Lemoine, Marc D., Eschenhagen, Thomas
Publicado 2021

Recapitulation of dyssynchrony-associated contractile impairment in asymmetrically paced engineered heart tissue

por Stenzig, Justus, Lemoine, Marc D., Stoter, Aaltje M.S., Wrona, Kinga M., Lemme, Marta, Mulla, Wesam, Etzion, Yoram, Eschenhagen, Thomas, Hirt, Marc N.
Publicado 2022

Outcome of catheter ablation of non-reentrant ventricular arrhythmias in patients with and without structural heart disease

por Schleberger, Ruben, Jularic, Mario, Salzbrunn, Tim, Hacke, Claudia, Schwarzl, Jana M., Hoffmann, Boris A., Steven, Daniel, Willems, Stephan, Lemoine, Marc D., Meyer, Christian
Publicado 2020

Genetic and Clinical Predictors of Left Atrial Thrombus: A Single Center Case-Control Study

por Springer, Adrian, Schleberger, Ruben, Oyen, Florian, Hoffmann, Boris A., Willems, Stephan, Meyer, Christian, Langer, Florian, Schnabel, Renate B., Kirchhof, Paulus, Schneppenheim, Reinhard, Lemoine, Marc D.
Publicado 2021

Chronic intermittent tachypacing by an optogenetic approach induces arrhythmia vulnerability in human engineered heart tissue

por Lemme, Marta, Braren, Ingke, Prondzynski, Maksymilian, Aksehirlioglu, Bülent, Ulmer, Bärbel M, Schulze, Mirja L, Ismaili, Djemail, Meyer, Christian, Hansen, Arne, Christ, Torsten, Lemoine, Marc D, Eschenhagen, Thomas
Publicado 2020

Atrial-like Engineered Heart Tissue: An In Vitro Model of the Human Atrium

por Lemme, Marta, Ulmer, Bärbel M., Lemoine, Marc D., Zech, Antonia T.L., Flenner, Frederik, Ravens, Ursula, Reichenspurner, Hermann, Rol-Garcia, Miriam, Smith, Godfrey, Hansen, Arne, Christ, Torsten, Eschenhagen, Thomas
Publicado 2018

Repolarization indicates electrical instability in ventricular arrhythmia originating from papillary muscle

por Münkler, Paula, Klatt, Niklas, Scherschel, Katharina, Kuklik, Pawel, Jungen, Christiane, Cavus, Ersin, Eickholt, Christian, Christoph, Jan, Lemoine, Marc D, Christ, Torsten, Willems, Stephan, Riedel, René, Kirchhof, Paulus, Meyer, Christian
Publicado 2022

Blinded Contractility Analysis in hiPSC-Cardiomyocytes in Engineered Heart Tissue Format: Comparison With Human Atrial Trabeculae

por Mannhardt, Ingra, Eder, Alexandra, Dumotier, Berengere, Prondzynski, Maksymilian, Krämer, Elisabeth, Traebert, Martin, Söhren, Klaus-Dieter, Flenner, Frederik, Stathopoulou, Konstantina, Lemoine, Marc D., Carrier, Lucie, Christ, Torsten, Eschenhagen, Thomas, Hansen, Arne
Publicado 2017

Case Report on: Very Early Afterdepolarizations in HiPSC-Cardiomyocytes—An Artifact by Big Conductance Calcium Activated Potassium Current (I(bk,Ca))

por Horváth, András, Christ, Torsten, Koivumäki, Jussi T., Prondzynski, Maksymilian, Zech, Antonia T. L., Spohn, Michael, Saleem, Umber, Mannhardt, Ingra, Ulmer, Bärbel, Girdauskas, Evaldas, Meyer, Christian, Hansen, Arne, Eschenhagen, Thomas, Lemoine, Marc D.
Publicado 2020

Regulation of APD and Force by the Na(+)/Ca(2+) Exchanger in Human-Induced Pluripotent Stem Cell-Derived Engineered Heart Tissue

por Ismaili, Djemail, Gurr, Katrin, Horváth, András, Yuan, Lei, Lemoine, Marc D., Schulz, Carl, Sani, Jascha, Petersen, Johannes, Reichenspurner, Hermann, Kirchhof, Paulus, Jespersen, Thomas, Eschenhagen, Thomas, Hansen, Arne, Koivumäki, Jussi T., Christ, Torsten
Publicado 2022

Human iPSC-derived cardiomyocytes cultured in 3D engineered heart tissue show physiological upstroke velocity and sodium current density

por Lemoine, Marc D., Mannhardt, Ingra, Breckwoldt, Kaja, Prondzynski, Maksymilian, Flenner, Frederik, Ulmer, Bärbel, Hirt, Marc N., Neuber, Christiane, Horváth, András, Kloth, Benjamin, Reichenspurner, Hermann, Willems, Stephan, Hansen, Arne, Eschenhagen, Thomas, Christ, Torsten
Publicado 2017

Low Resting Membrane Potential and Low Inward Rectifier Potassium Currents Are Not Inherent Features of hiPSC-Derived Cardiomyocytes

por Horváth, András, Lemoine, Marc D., Löser, Alexandra, Mannhardt, Ingra, Flenner, Frederik, Uzun, Ahmet Umur, Neuber, Christiane, Breckwoldt, Kaja, Hansen, Arne, Girdauskas, Evaldas, Reichenspurner, Hermann, Willems, Stephan, Jost, Norbert, Wettwer, Erich, Eschenhagen, Thomas, Christ, Torsten
Publicado 2018

Ablation of Outflow Tract Arrhythmias in Patients With and Without Structural Heart Disease—A Comparative Analysis

por Schleberger, Ruben, Riess, Jan, Brauer, Anika, Pinnschmidt, Hans O., Rottner, Laura, Moser, Fabian, Moser, Julia, Kany, Shinwan, My, Ilaria, Lemoine, Marc D., Reissmann, Bruno, Meyer, Christian, Metzner, Andreas, Ouyang, Feifan, Kirchhof, Paulus, Rillig, Andreas
Publicado 2022

Comparison of 10 Control hPSC Lines for Drug Screening in an Engineered Heart Tissue Format

por Mannhardt, Ingra, Saleem, Umber, Mosqueira, Diogo, Loos, Malte F., Ulmer, Bärbel M., Lemoine, Marc D., Larsson, Camilla, Améen, Caroline, de Korte, Tessa, Vlaming, Maria L.H., Harris, Kate, Clements, Peter, Denning, Chris, Hansen, Arne, Eschenhagen, Thomas
Publicado 2020

The impact of ultra-high-density mapping on long-term outcome after catheter ablation of ventricular tachycardia

por Schleberger, Ruben, Schwarzl, Jana M., Moser, Julia, Nies, Moritz, Höller, Alexandra, Münkler, Paula, Dinshaw, Leon, Jungen, Christiane, Lemoine, Marc D., Maury, Philippe, Sacher, Frederic, Martin, Claire A., Wong, Tom, Estner, Heidi L., Jaïs, Pierre, Willems, Stephan, Eickholt, Christian, Meyer, Christian
Publicado 2022

Pulsed-field ablation-based pulmonary vein isolation: acute safety, efficacy and short-term follow-up in a multi-center real world scenario

por Lemoine, Marc D., Fink, Thomas, Mencke, Celine, Schleberger, Ruben, My, Ilaria, Obergassel, Julius, Bergau, Leonard, Sciacca, Vanessa, Rottner, Laura, Moser, Julia, Kany, Shinwan, Moser, Fabian, Münkler, Paula, Dinshaw, Leon, Kirchhof, Paulus, Reissmann, Bruno, Ouyang, Feifan, Sommer, Philipp, Sohns, Christian, Rillig, Andreas, Metzner, Andreas
Publicado 2022

Translational investigation of electrophysiology in hypertrophic cardiomyopathy

por Flenner, Frederik, Jungen, Christiane, Küpker, Nadine, Ibel, Antonia, Kruse, Martin, Koivumäki, Jussi T., Rinas, Anna, Zech, Antonia T.L., Rhoden, Alexandra, Wijnker, Paul J.M., Lemoine, Marc D., Steenpass, Anna, Girdauskas, Evaldas, Eschenhagen, Thomas, Meyer, Christian, van der Velden, Jolanda, Patten-Hamel, Monica, Christ, Torsten, Carrier, Lucie
Publicado 2021

ACTN2 Mutant Causes Proteopathy in Human iPSC-Derived Cardiomyocytes

por Zech, Antonia T. L., Prondzynski, Maksymilian, Singh, Sonia R., Pietsch, Niels, Orthey, Ellen, Alizoti, Erda, Busch, Josefine, Madsen, Alexandra, Behrens, Charlotta S., Meyer-Jens, Moritz, Mearini, Giulia, Lemoine, Marc D., Krämer, Elisabeth, Mosqueira, Diogo, Virdi, Sanamjeet, Indenbirken, Daniela, Depke, Maren, Salazar, Manuela Gesell, Völker, Uwe, Braren, Ingke, Pu, William T., Eschenhagen, Thomas, Hammer, Elke, Schlossarek, Saskia, Carrier, Lucie
Publicado 2022

Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy

por Prondzynski, Maksymilian, Lemoine, Marc D, Zech, Antonia TL, Horváth, András, Di Mauro, Vittoria, Koivumäki, Jussi T, Kresin, Nico, Busch, Josefine, Krause, Tobias, Krämer, Elisabeth, Schlossarek, Saskia, Spohn, Michael, Friedrich, Felix W, Münch, Julia, Laufer, Sandra D, Redwood, Charles, Volk, Alexander E, Hansen, Arne, Mearini, Giulia, Catalucci, Daniele, Meyer, Christian, Christ, Torsten, Patten, Monica, Eschenhagen, Thomas, Carrier, Lucie
Publicado 2019

Human Engineered Heart Tissue Patches Remuscularize the Injured Heart in a Dose-Dependent Manner

por Querdel, Eva, Reinsch, Marina, Castro, Liesa, Köse, Deniz, Bähr, Andrea, Reich, Svenja, Geertz, Birgit, Ulmer, Bärbel, Schulze, Mirja, Lemoine, Marc D., Krause, Tobias, Lemme, Marta, Sani, Jascha, Shibamiya, Aya, Stüdemann, Tim, Köhne, Maria, von Bibra, Constantin, Hornaschewitz, Nadja, Pecha, Simon, Nejahsie, Yusuf, Mannhardt, Ingra, Christ, Torsten, Reichenspurner, Hermann, Hansen, Arne, Klymiuk, Nikolai, Krane, M., Kupatt, C., Eschenhagen, Thomas, Weinberger, Florian
Publicado 2021